Force and Function at the Nanoscale
We will study some of the fundamental forces at the nanoscale and look at the role of key concepts such as entropy. We will also learn how we can visualise and measure the nanoscale structures that form.
The nanoscale world is very different from our regular experience. Thermal energy pushes and pulls everything towards a state of disorder whilst nanoscale forces allow for materials to resist this and stay together. We will study some of the fundamental forces at the nanoscale and look at the role of key concepts such as entropy. We will also learn how we can visualise and measure the nanoscale structures that form.
While the forces we will study operate over distances as small as 1 nanometre we will explore how these concepts are responsible for phenomena in our everyday world we often don’t even think about:
- Why is a droplet spherical?
- What is going on when you scramble an egg?
- How can a gecko walk across a perfectly smooth ceiling?
- Why do you use soap when you wash?
- Why don’t oil and water mix?
The Structure of Galaxies
This module will develop your current understanding of the various large-scale physical processes that dictate the formation, evolution and structure of galaxies, from when the Universe was in its infancy to the present day.
You’ll explore a range of topics, starting with the fundamentals of observational techniques used by astronomers for understanding the structure of our own galaxy, the Milky Way. We will then look at the more sophisticated ways of unpicking the physics that drives the complexity we see throughout the population of galaxies in the Universe.
Specifically, in this module, you will study:
- The structure of the Milky Way – how we determine the structure of the Milky Way, its rotation curve and what this implies for its dark matter content
- Properties of galaxies in the Universe – how astronomers classify galaxies, the properties of the different classes and how their constituents vary between classes
- Dynamics of galaxies – kinematics of the gas and stars in galaxies, why spiral arms form, the theory of epicycles, bar formation, different types of orbits of matter within galaxies
- Active galaxies – radio galaxies, quasars and active galactic nuclei, super-massive black holes
- The environment of galaxies – how the environment that a galaxy resides in affects its evolution and structure
- Galaxy evolution – observations of galaxy evolution from the early Universe to the present day, models of galaxy evolution.
Introduction to Cosmology
Cosmology is the scientific study of the Universe as a whole. It aims to understand what the Universe is made of, and its evolution from the Big Bang until today (and into the future).
You’ll study:
- observational evidence for the Big Bang
- how the expansion of the Universe depends on its contents and geometry
- how the contents of the Universe evolve as it expands and cools
- dark matter and dark energy: observational evidence and the latest theoretical models
- inflation, a proposed period of accelerated expansion in the very early Universe
From Accelerators to Medical Imaging
Science is the cornerstone of modern healthcare. For example, in the UK’s National Health Service (NHS) more than 80% of clinical decisions are informed by scientific analysis.
In this module, we will explore some of the critical technologies that underpin these decisions. The course begins by exploring particle accelerators, and how they are used to create, for example, high energy photons or anti-matter particles. We will then see how these are used to either diagnose or treat illnesses such as cancer.
We will look closely at medical imaging techniques such as X-ray computed tomography (the CT scan), exploring the mathematics of how high-definition images of the body can be formed. We will cover nuclear medicine – how radiation can be used to track the function of organs in the body – and how advanced mathematical models feed into diagnostic decisions.
Functional Medical Imaging
The techniques for magnetic resonance imaging (MRI) and spectroscopy (MRS) are explored. The course aims to introduce the brain imaging technique of functional magnetic resonance imaging (fMRI), giving an overview of the physics involved in this technique. The electromagnetic techniques of electroencephalography (EEG) and magnetoencephalography (MEG) will then be outlined, and the relative advantages of the techniques described.
Imaging and Manipulation at the Nanoscale
The invention of the scanning tunneling microscope (STM) in the 1980s has led to a revolution in the imaging of surfaces and has provided an enormous stimulus for the development of nanoscience. The operation of a scanning probe microscope relies on the interaction between a local probe and a surface. A family of techniques has been derived from the STM which exploit a range of different forces and other interactions for image formation. The most widely-used of these techniques is atomic force microscopy which, unlike, STM, can be used to image insulating samples. In this module the focus will be on the development of physical models to describe the interaction between a local point-like probe and a surface. The operation of the STM will be considered in detail together with design considerations which are common across all scanning probe microscopes. In the second half of the course, forces between the tip and sample will be considered and methods for measuring these interactions will be discussed. The probe-surface interaction can also be used to modify the surface with a specificity which can result in placement of single atoms and molecules and these patterning processes will be discussed. Throughout the course images from the current research literature will be introduced to inform students of the range of possible applications of this these techniques.
Molecular Biophysics
This module explores how physics-based techniques are used to gain insight into complex molecular systems of biological relevance. In studying the physics underpinning this area of research where chemistry, biology and physics all overlap, we will draw on principles derived from quantum mechanics and statistical physics to develop a better understanding of the biomolecular world.
Physics has made significant contributions in our efforts to understand the underlying molecular principles of life. For instance, physics plays an important role in the development of sophisticated methods that make it possible to measure the complex structure of biological molecules and their mutual interactions and dynamics. Two important groups of such biomolecules that will be discussed in the module are proteins and deoxynucleic acids (DNA).
Topics covered in this module include:
- Introduction into the important classes of complex biomolecules
- What are the underlying principles that make molecules to acquire a functional 3-dimensional structure?
- How can molecular structure be measured with high accuracy?
- How do molecular motors work and can molecules carry out directional motion?
- How can molecular forces and distances be measured between individual molecules.
Nonlinear Dynamics and Chaos
How can complicated nonlinear mechanical, electrical and biological systems be understood? In this module you will develop your knowledge of classical mechanics of simple linear behaviour to include the behaviour of complex nonlinear dynamics. You’ll learn about the way in which nonlinear deterministic systems can exhibit essentially random behaviours, and approaches to understand and control them.
You’ll learn:
- In-depth knowledge of nonlinear dynamics in continuous and discrete classical systems
- Practical skills in using analytical, geometric and numerical approaches to analyse dynamics in nonlinear systems of various dimensions
- Methods to understand and create beautiful fractals through simple iteration rules.
Atmospheric and Planetary Physics
In this module you will explore the physics of planets and their atmospheres — a topic that is at the forefront of modern astrophysics and planetary science.
In the last few decades, the discovery of thousands of exoplanets beyond our Solar System has revolutionised the study of planets and their atmospheres.
Closer to home, understanding the physical processes at play in the Earth’s atmosphere remains vital for predicting weather and climate.
You’ll study:
- Exoplanet detection methods and the physics of planet formation
- The structure, temperature and composition of planetary atmospheres
- Atmospheric dynamics
- Exoplanet atmospheres and the search for biosignatures