In this year, you will be able to focus on your favourite areas of genetics, with a good degree of choice.
This year's focus is health and disease in humans, other animals and plants. You will learn about the basis of disease, pathogens and parasites, evolutionary origins and biodiversity.
Bacterial Genes and Development
Molecular events that occur during the control of gene expression in bacteria will be explored. You'll learn by considering case studies, which will show you how complex programmes of gene action can occur in response to environmental stimuli. You will also study the regulation of genes in pathogenic bacteria.
Evolutionary Biology of Animals
Introduces key evolutionary concepts and their application in the animal kingdom. Areas you will study include the history of evolutionary thinking, natural selection versus the neutral theory, sexual selection and human evolution.
The Genome and Human Disease
In this module you will learn about the structure and function of the eukaryotic genome, including that of humans, and the approaches that have led to their understanding. You will learn about techniques that are employed to manipulate genes and genomes and how they can be applied to the field of medical genetics. By using specific disease examples, you will learn about the different type of DNA mutation that can lead to disease and how they have been identified. Practical elements will teach you about basic techniques used in medical genetics such as sub-cloning of DNA fragments into expression vectors. Practical classes and problem based learning will be used to explore the methods used for genetic engineering and genome manipulation.
Higher Skills in the Biological Sciences
You will gain confidence and skills in using the biological literature. Your knowledge of statistical methods will be reinforced and developed, and, through designing your own experiments, you will learn to build statistical principles into their experimental methodologies. Through writing a dissertation, you will learn to collate information from multiple sources, and describe a field clearly and concisely, revealing the state of present knowledge and prospects for future developments.
Students MUST take a minimum of 40 credits and a maximum of 60 credits from the modules below:
Animal Behaviour and Physiology
A comprehensive introduction to the study of animal behaviour, from the physiological and genetic bases of behaviour to its development through learning and its adaptive significance in the natural environment. Through practical classes, you will learn about the physiological basis of fundamental behaviours. Using examples from across the animal kingdom, you will learn how predictive modelling, experimental and observational approaches integrate to explain how and why animals behave as they do.
Examines the basic concepts of vertebrate embryonic development. You will discuss specific topics including germ cells, blood and muscle cell differentiation, left-right asymmetry and miRNAs. The teaching for this module is delivered through lectures.
Infection and Immunity
You will study microbiology, learning about pathogenic microbes including viruses, fungi, parasites and the roles of bacteria in health and disease. You will learn how the body generates immunity; the causes of diseases associated with faulty immune responses will be considered. In applied microbiology you will be introduced to recombinant DNA technology and prokaryotic gene regulation.
Studying this module, you'll be able to explain how the nervous system develops, is organised, and processes information. This will be achieved through presentation of comparative invertebrate and vertebrate studies, consideration of evolutionary concepts, and a detailed analysis of the development, structure, and function of the mammalian brain. The lecture sessions are complemented by workshops on Drosophila and chick embryo development, on the neuroanatomy of the human spinal cord, and dissection of pig brains subject to the availability of tissue.
You'll cover the key groups of eukaryotic and prokaryotic microorganisms relevant to microbial biotechnology, principles of GM, and strain improvement in prokaryotes and eukaryotes. The impact of “omics”, systems biology, synthetic biology and effects of stress on industrial microorganisms are explored, alongside the activities of key microorganisms that we exploit for biotechnology.
Pharmacological Basis of Therapeutics
Primary objective of the module
This module will examine in depth the analysis of drug action, and its application to the design and use of current therapeutics.
This module will examine in depth the analysis of drug action, and its application to the design and use of current therapeutics. We will define what drugs are, the different ways they act at the cellular and molecular level, and pharmacokinetic principles underlying drug absorption, distribution, metabolism and elimination. This framework will provide the basis to explore the rationale and goals of treatment for clinical therapeutic case studies. These will highlight major current challenges to human health – in cardiovascular and respiratory disease, diabetes and obesity, CNS disorders, cancer and infectious disease. Overall, the student will develop a deep understanding of what the discipline of pharmacology represents, and its application to both basic biological research and current and future medical advances.
From Genotype to Phenotype and Back
This module studies transporters and channels, groups of proteins responsible for controlling the flow of substances across lipid bilayers that are critical for cellular homeostasis. You will learn the basics of transporter and channel biology, and then apply this knowledge to design virtual experiments, the simulated results of which would gradually reveal the molecular basis of a transporter or channel related disease. You will design a series of “virtual experiments”, with appropriate controls, in order to probe the function of a particular gene in a physiological condition.
Neurobiology of Disease
This module will teach you the underlying neurophysiology and pathology associated with several common CNS disorders and the neuropharmacology of currently available medication. You will learn about the neurotransmitters and pathways involved in normal brain function and how changes in these contribute to abnormal function. You will also decipher the pharmacological mechanisms of drugs used to treat these CNS disorders. You will cover numerous human diseases including those with great significance such as Alzheimer's disease, epilepsy, schizophrenia and autism.
The Green Planet
This module explores the evolution of key plant systems through deep time, and the significance of this process for understanding modern ecology and food security. You will learn about the challenges that plants faced when moving onto land and evolutionary innovations within the early spermatophytes. You will also gain an understanding of the power of natural selection in producing plant diversity over deep time.
The above is a sample of the typical modules we offer but is not intended to be construed and/or relied upon as a definitive list of the modules that will be available in any given year. Modules (including methods of assessment) may change or be updated, or modules may be cancelled, over the duration of the course due to a number of reasons such as curriculum developments or staffing changes. Please refer to the module catalogue
for information on available modules. This content was last updated on