2.2.3 Cystic fibrosis A different model for the genetic tests of the future is screening for cystic fibrosis (CF). This is a DNA-based test, which became possible after the gene involved in CF was identified in 1989. CF is a recessive disease, and it should be easy to test to see if prospective parents carry a mutated allele. A simple mouthwash yields enough cells for DNA extraction. If both partners are carriers, they can consider further counselling before conception, and/or pre-natal testing of any potentially
Babbage: Samsung's meltdown
Our technology editor examines the long-term fallout after Samsung's flagship smartphone is pulled from production. The Food and Drug Administration's approval of a new drug for muscular dystrophy proves controversial and Matt Kaplan explains why higher-class people spend less time looking at their fellow humans
3 Silences and concealment Anthropologists and psychoanalysts use the term ‘taboo’ to describe forbidden activities, feelings or relationships. All societies seem to have particular rules and rituals to deal with bodily functions, sexuality and death, sometimes expressed in terms of hygiene or religion, and these keep them separated off from everyday life. When social rules function well they are invisible. We only notice them when we have committed a faux pas and caused embarrassment. Marie very quick
Tasting menu: Audio highlights from the April 2nd 2016 edition
This week: some self-help for white-collar workers, signs of happier times for Baghdad’s restaurant scene and a lucrative trade in souvenirs from America’s presidential campaign
Why Jupiter Has a Giant Red Spot | How the Universe Works
Jupiter's weather doesn't come from the sun; it comes from deep within the planet, itself. This heat and the planet's incredible rotation speed create the mega storms on Jupiter's surface--including the great red spot. (02:18)
Building a Business: Evaluating a Venture Idea
Pegram Harrison, Fellow in Entrepreneurship at the Said Business School, presents the 2nd lecture of the 2011/12 Building a Business lecture series.
2.2.4 Longer-term considerations Something else to ponder is the effect that screening might have on the longer-term incidence of disease and (not the same thing) on the incidence of gene variants linked to disease. Sometimes, the impact on a disease can be dramatic. Take thalassaemia, a haemoglobin disorder similar to sickle cell disease, in which premature destruction of haemoglobin-containing red blood cells leads to anaemia. It is relatively common in some Mediterranean countries. Like sickle cell disease, it is understo
1.1 Why does it hurt? The relief or avoidance of pain must be one of the major driving forces behind medical research. In this course we start the discussion about relief of pain. When we experience the sensation of pain it is likely that something is happening that the brain needs to know about, so it can direct us to whatever damage-limiting action is needed. We hurt because we have genes that constructed a body able to feel pain. Without such a mechanism it is likely that life would be much shorter,
535 GG Anyways or Anyway? Topic Sentences
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Evolution Ep4: The Evolutionary Arms Race (1/6)
Explore our own spiraling arms race with microorganisms -- the only real threat to our existence -- and trace the alarming spread of resistance among pathogens that cause disease.This documentary is suitable for high school grades. Run time 10:54.
What Is a Semicolon?
A semicolon is used when a writer wants their reader to take an extended pause. Teacher presents examples on her computer screen. (01:20)
The History of Vaccines
The History of Vaccines - Kids are taught about the unique ways in which animals have adapted and evolved to survive in their surroundings. Humans have created their own ways of adapting to the elements. (04:17)
4.3.2 Removal of CO Under fuel-lean conditions (excess O2), the oxidation of CO has been studied over a very large range of single crystals and model noble metal catalysts, one of the most intensively investigated examples being the Pd(111) surface. Although this metal is not a component of the current three-way catalyst used in the UK, it is worth considering the results in some detail for a number of reasons. The reaction on metals such as Pt is in many ways similar to that on Pd and, in any
Lord Owen: British Foreign Policy after Brexit
In this IPR Public Lecture Lord David Owen – former Foreign Secretary and founder of the Social Democratic Party – discusses his advocacy for leaving the EU, and explores what foreign policy might look like after Brexit.
This IPR Public Lecture took place on 18 January 2018.
1.4.1 Introduction Up to now I have focused on the claims of the antisweatshop movement and the counter-claims of those who contest the purely negative conclusions drawn about the exploitation of another country's poor. To that end, I have, at various moments, touched on issues of demands to take responsibility: whether, for instance, responsibility for sweatshops should be divided up in some way between all those connected to the market system which gives rise to them, or placed firmly at the door of the big r
Learning outcomes After studying this course, you should be able to: understand that genes are the units of inheritance for individual characteristics and also may contribute to susceptibility to certain diseases understand the number of chromosomes that make up the human genome and where they are located within the cell understand something of the immense scale of the human genome project understand how gametes are produced by the process of meiosis a
3.4 Evaluation at the end of a project Different types of evaluation may take place at the end of a project. A common one is determining the extent to which the project outcomes have been achieved. This is often done in a meeting of the sponsor, key stakeholders and project team leaders, and sometimes informed by reports from key perspectives. An evaluation of this nature may be the final stage of the project, and the main purpose might be to ensure that the project has met all of the contracted expectations and can be ‘signed o
8.2 Chromosome scaffolds Most of the chromosomal DNA chains within the interphase nucleus are believed to be held on a scaffold or backbone structure made from various proteins, with loops of between 20 and 200 kb extruding from attachment sites. This chromosome structure is shown schematically in Figure 40. The scaffold, as well as permitting further compaction, serves to bring the DNA together in organised regions. There are many different protein components of these scaffolds, amongst them DNA topoisomerases.
Introduction This is the fifth and final unit in the MSXR209 series on mathematical modelling. In this unit we revisit the model developed in the first unit of this series on pollution in the Great Lakes of North America. Here we evaluate and revise the original model by comparing its predictions against data from the lakes before finally reflecting on the techniques used. This unit, the fifth in a series of five, builds on ideas developed and introduced in Modelling pollution in the Great Lakes
Learning outcomes After studying this course, you should be able to: understand the legal framework of the Health and Safety at Work etc. Act 1974 and Regulations associated with it understand the employers’, employees’ and visitors’ duties evaluate hazards and risks in order to carry out a risk assessment understand the legal requirement to report any accident or dangerous occurrence develop risk assessments for scientific laborat
