Acknowledgements

Grateful acknowledgement is made to the following sources for permission to reproduce material in this course:

Couse image: Mike in Flickr made available under Creative Commons Attribution-NonCommercial-ShareAlike 2.0 Licence.

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Stem cells: the future of medicine?
Dr Adam Giangreco views stem cell research as the best promise for medical breakthroughs over the next few decades. Dr Giangreco, a recent recipient of a major European Research Council grant, explains how he is exploring new treatments for lung damage and why funding stem cell research is so vital. 6 October is International Stem Cell Awareness Day. UCL Centre for Stem Cells and Regenerative Medicine: http://www.ucl.ac.uk/stemcells/ For UCL lectures on stem cell research (link to iTunesU): http
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Chemical and Environmental Behaviour of Materials: Fuel Cells
This set of animations demonstrates the principles of a solid oxide fuel cell and a proton exchange membrane cell. From TLP: Fuel Cells
Author(s): Derek Fray, University of Cambridge,Steve Mounsey,

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Douglas Melton, Harvard University: "Stem Cell Challenges in Biology and Public Policy" - April 10,
Douglas Melton will discuss the biology and public policy challenges surrounding stem cell research. The potential of human embryonic stem cells for understanding human development and finding new therapies will be presented. Dr. Melton is a cell and molecular biologist as well as an advocate of embryonic stem cell research. His research focuses on the developmental biology of the pancreas. One of the primary goals of his work is to understand how human embryonic stem cells differentiate into pa
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Virtual laboratories in Molecular and Cell Biology - Immuno-electron-microscopy
A virtual laboratory that includes immuno-gold labelling and transmission electron micrography (immuno-EM). It allows the student to study intracellular-traffic pathways of two cell-surface receptor molecules, following stimulation of the cells with their specific ligand, for different time periods. The programme first introduces the theory underlying the techniques and includes a video of EM work in a real laboratory. The student is then taken through a series of questions which requires them t
Author(s): David Male, Ignacio Romero, Jane Loughlin - The Op

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Virtual laboratories in Molecular and Cell Biology - SDS-PAGE
A protein analysis laboratory using SDS-PAGE, western-blotting and endoprotease digestion. The programme includes a section on the theory of the techniques, a video demonstration in a real laboratory, and a series of questions which guide the students through the structural analysis of model proteins (3 are included). Students go to the virtual laboratory and devise their own experiments in order to determine the molecular weight, subunit composition etc of the proteins. Results (gels and blots)
Author(s): David Male, Ignacio Romero, Jane Loughlin - The Op

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5.4 Inspiratory drive

The supply of oxygen to tissues such as the heart, liver and WAT is, under euthermic conditions, invariably linked to and dependent upon local blood flow and pulmonary function. However, as we have already seen, under conditions in which blood flow is reduced to a trickle, the control of energy supply switches to local adaptations in the capillaries and tissue cells, including the oxygen affinity of erythrocyte haemoglobin, the supply and metabolism of respiratory fuels and the rate of protei
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Interdisciplinary Science Nanoscale Frontiers Student Document
In this module you will explore basic cell biology and cell imaging techniques. using quantum dots. You will also be introduced to the flow of genetic information through the cell, whereby the DNA inherited by an organism leads to specific traits by dictating the synthesis of proteins.
Author(s): Chris Willmott,Mervyn Roy,Derek Raine

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Low magnification SEM image of open cell polyurethane foam
If a gas is injected into a liquid it forms a cellular foam structure. When a thermoset prepolymer of low viscosity is foamed, the polymer can drain from the cell walls (driven by surface tension) before it sets at the cell edges, leaving an open-celled foam. The cell edges have three concave sides, giving rise to the tri-cuspid cross section visible at the bottom of this image. The average co-ordination number for the nodes (where struts meet) is four, giving tetrahedral junctions.
Author(s): Dr J A Elliott, Department of Materials Science an

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X-ray tomography image of open cell polyurethane foam
If a gas is injected into a liquid it forms a cellular foam structure. When a thermoset prepolymer of low viscosity is foamed, the polymer can drain from the cell walls (driven by surface tension) before it sets at the cell edges, leaving an open-celled foam. The cell edges have three concave sides. The average co-ordination number for the nodes (where struts meet) is four, giving tetrahedral junctions. The deformation behaviour of the foam was observed by X-ray microtomography at the ESRF in Gr
Author(s): Dr J A Elliott, Department of Materials Science an

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Open celled aluminium foam produced by infiltration of sintered salt
This is an inexpensive route for the production of open celled foams. It allows a high degree of control over cell size and shape, and results in relatively uniform morphology. The interconnectivity of pores can be controlled by varying the degree of sintering of the precursor.
Author(s): J A Curran, Department of Materials Science and Me

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Fe, C 1.0 (wt%), hypereutectoid alloy
This secondary electron SEM image shows the cementite delineating prior austenite grain boundaries with a thin layer. The amount of proeutectoid phase is very low, with the majority of the area being taken by the pearlite eutectoid. Again each pearlite cell has a different orientation with the ferrite phase being selectively etched.
Author(s): Prof T W Clyne, Department of Materials Science an

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Alporas' closed cell aluminium foam
Additions are made to molten aluminium or aluminium alloy to modify the melt viscosity and make it suitable for foaming. 1 to 3 wt% titanium hydride is then added to the melt, and this foams the melt by releasing hydrogen. The foamed melt solidifies to yield a closed cellular structure with an average cell size of 4.5 mm
Author(s): Dr V Gergely, Department of Materials Science and

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Fe, C 1.0 (wt%), hypereutectoid alloy
This secondary electron SEM image shows the cementite delineating prior austenite grain boundaries with a thin layer. The amount of proeutectoid phase is very low, with the majority of the area being taken by the pearlite eutectoid. Again each pearlite cell has a different orientation with the ferrite phase being selectively etched.
Author(s): Prof T W Clyne, Department of Materials Science an

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SEM image of open cell polyurethane foam
If a gas is injected into a liquid it forms a cellular foam structure. When a thermoset prepolymer of low viscosity is foamed, the polymer can drain from the cell walls (driven by surface tension) before it sets at the cell edges, leaving an open-celled foam. The cell edges have three concave sides, giving rise to the tri-cuspid cross section visible at the bottom of this image. The average co-ordination number for the nodes (where struts meet) is four, giving tetrahedral junctions.
Author(s): J A Curran, Department of Materials Science and Me

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Medicine Games: Control of the Cell Cycle
Play a game and find out about a Nobel Prize awarded discovery or work! In this game you are to take on the job as a Cell Division Supervisor. Are you familiar with the different phases in the cell cycle? If not, maybe you should pay extra attention to the image of the cell cycle in the introduction.
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Cell Differentials
Cell Differentials offers a visual dataset of white blood cells that gives students practice in developing strategies and techniques for the recognition of these blood cell types. Over 100 different cell images are randomly presented with feedback on successful identification. In traditional labs, the recognition of white blood cell types can be compromised by several factors. Developmental changes can make recognition difficult and some cell types exhibit similar features. Microscopy can be a
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CuraÁao
CuraÁao is a computer program that simulates the sterile insect release method (SIRM) of pest population suppression, first conceived by E. F. Knipling (1955). The user can investigate the effects of several variables on the effectiveness of the method and discover what happens when some of the basic assumptions of the model are relaxed or violated in some way. The user should gain some understanding of the sorts of things that complicate the application of the technique in situations that are
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Cell Biology Improvement Drive
Wikiversity participants with an interest in Cell biology can participate in the "Cell biology improvement drive". This Learning Project is a service-oriented Wikiversity project devoted to improvement of Cell biology articles at Wikipedia and development of the Wikibooks textbook about Cell biology. Participants in the project can become involved in the construction of new Wikiversity pages that are concerned with Cell biology. This "Cell biology improvement drive" also includes improvement of
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