20.441J Biomaterials-Tissue Interactions (MIT)
This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following imp
Author(s): Ioannis Yannas,Myron Spector

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CuraÁao
CuraÁao is a computer program that simulates the sterile insect release method (SIRM) of pest population suppression, first conceived by E. F. Knipling (1955). The user can investigate the effects of several variables on the effectiveness of the method and discover what happens when some of the basic assumptions of the model are relaxed or violated in some way. The user should gain some understanding of the sorts of things that complicate the application of the technique in situations that are
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Cell Differentials
Cell Differentials offers a visual dataset of white blood cells that gives students practice in developing strategies and techniques for the recognition of these blood cell types. Over 100 different cell images are randomly presented with feedback on successful identification. In traditional labs, the recognition of white blood cell types can be compromised by several factors. Developmental changes can make recognition difficult and some cell types exhibit similar features. Microscopy can be a
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Medicine Games: Incredible Megacell Game
Play a game and find out about a Nobel Prize awarded discovery or work! The compartments of the cell, the organelles, are so small that it was impossible to study their structure until the electron microscope became available in 1938. Albert Claude, Christian de Duve and George E. Palade were awarded the Nobel Prize in Physiology or Medicine in 1974 for developing methods making it possible to take a closer look at the organelles and for discovering some of them.
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Privacy
Though it brings us many benefits, the march of technology makes an encompassing surveillance network seem almost inevitable, and radically changes our expectations of privacy. We owe many of the expectations of privacy we used to enjoy to a combination of immature technology and insufficient manpower to monitor us. But these protective inefficiencies are giving way to technologies of data processing and digital surveillance that will change our beliefs about privacy. We are widely tracked by pu
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Essential Science for Teachers: Life Science: Session 2. Classifying Living Things
How can we make sense of the living world? During this session, a systematic approach to biological classification is introduced as a starting point for understanding the nature of the remarkable diversity of life on Earth.,This clip is a graphic showing the basis for photosynthesis.
Author(s): Harvard-Smithsonian Center for Astrophysics

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Cell Biology and Cancer
This curriculum supplement brings into the classroom new information about some of the exciting medical discoveries being made at the National Institutes of Health (NIH) and their effects on public health. This set is being distributed to teachers around the country free of charge by the NIH to improve science literacy and to foster student interest in science. The first three supplements in the series are designed for use in senior high school science classrooms: Emerging and Re-emerging Infect
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Mitochondrial Control Region
Every human cell has a "second" genome, found in the cell's energy-generating organelle, the mitochondrion. In fact, each mitochondrion has several copies of its own genome, and there are several hundred to several thousand mitochondria per cell. This means that the mitochondrial (mt) genome is highly amplified. While each cell contains only two copies of a given nuclear gene (one on each of the paired chromosomes), there are thousands of copies of a given mt gene per cell. Because of this high
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(Video) Nobel Lecture Series - Eric Accili.
Eric Accili, SFU kinesiology professor, on work of Rod MacKinnon who won the Nobel Prize for Chemistry for producing an image of cell membrane channels.
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Assembly of Proteins in Membranes II from the course General Biochemistry and Molecular Biology
General Biochemistry and Molecular Biology - Fall 2006. This course covers molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and c
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7.340 Regenerative Medicine: from Bench to Bedside (MIT)
Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signaling molecules. We will discuss the use of such factors for in vitro tissue production. We will also study the cellular mechanisms involved in the cl
Author(s): Petra Simic

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5.3.1 Allosteric regulation
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Author(s): The Open University

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Stem Cells: Programming and Personalized Medicine
After years of relentless lab work, rising and falling expectations, and the challenge of a sometimes hostile public, Rudolf Jaenisch says, “The scenario that looked like a fantasy … has come closer to reality. We can study complex human diseases in a Petri dish and potentially contribute to therapy.” In this l
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5.2 All proteins bind other molecules
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Author(s): The Open University

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Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2

Proteins
In this unit we explore how proteins are the 'doers' of the cell. They are huge in number and variety and diverse in structure and function, serving both the structural building blocks and the functional machinery of the cell. Just about every process in every cell requires specific proteins. The basic principles of protein structure and function which are reviewed in this unit are crucial to understanding how proteins perform their various roles.
Author(s): The Open University

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Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2

Keynote Presentation: Academic Perspectives
Very simply stated, systems biology attempts to “capture the dynamic nature of living systems.” To accomplish this, says Hood, you “have to bring together the flavors of biology, chemistry, computer science, engineering and physics,” among others. It’s a vast area to tackle. But with tools like the internet and digital
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Bioengineering at MIT: Building Bridges Between the Sciences, Engineering and Health Care (Part Two
Glycomics, the study of sugars’ role in living systems, is a relative newcomer to the revolution in molecular biology. In fact, Ram Sasisekharan remembers how colleagues told him “not to work on carbohydrates -- that it was useless.” But his research has shown that glycans, observed as long chains or intricat
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Nanotechnology and the Study of Human Diseases
Subra Suresh fleshes out the promise of nanotechnology, at least in regard to our understanding of disease. His talk, which focuses on malaria and its impact on red blood cells, demonstrates how the fields of engineering, biology and medicine are converging.

To function properly, he explains, a red blood cel

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Metastasis
No diagnosis of cancer is welcome, but some scenarios are more dreaded than others. Richard Hynes discusses what happens “when cells in the primary tumor lose their sense of address and wander off to places they’re not supposed to go.” His talk lays out the process of invasion, by which the cancer spreads into
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Imperative of Science and Technology in Accelerating African and Rwandan Development
The news these days from Africa isn’t all bad. In fact, in some places, it’s downright hopeful, as Rwandan President Paul Kagame attests. “Our continent is no longer all about violence and disease and human disasters that scarred many African countries in recent decades,” says Kagame. “We are now becoming a continen
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