GSC 11: Sarah Hunter
By: psterk1 EBI Metagenomics Portal. Sarah Hunter (European Bioinformatics Institute). Please note this video is incomplete. The 11th Genomic Standards Consortium Meeting (GSC 11), held at The Wellcome Trust Conference Centre, Hinxton, Cambridge, UK, April 4-6, 2011 (http://gensc.org/gc_wiki/index.php/GSC_11)
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1.3 Most receptors are on the cell surface

Water-soluble signalling molecules cannot cross the membrane lipid bilayer, but bind to specific receptors embedded in the plasma membrane. The receptors have an extracellular domain that binds the signalling molecule, a hydrophobic transmembrane domain and an intracellular domain.

Binding of a ligand induces a conformational change in the receptor, in particular that of its intracellular region. It is this conformational change that activates a relay of intracellular signalling molecul
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8.6Léxico básico


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Virtual Maths, Shapes, Space and Measure, Demonstration of a Theodolite Survey in action
Using a theodolite to calculate the height of a building, demonstration 'in the field', includes interactive simulation tools and formulae
Author(s): Leeds Metropolitan University

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Radio Lingua Network News: 26 September 2008
Happy European Day of Languages to all our listeners! By way of joining in this international celebration of languages and language-learning we're delighted to introduce eight new podcasts today. We're adding Catalan, Danish, French, Japanese, Mandarin and Romanian to our One Minute Languages series; we're introducing our first podcast for English learners - Write Back Soon will help learners master Phrasal Verbs; and we're finally announcing the long-awaited sequel to Coffee Break Spanish: it's
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Reconfiguring Architectural Space using Generative Design and Digital Fabrication: A Project Based C
This paper discusses a course that addresses the integration between generative design and digital fabrication in the context of reconfiguring architectural space. The objective of the course, offered for 3rd year architecture students at the Department of Architecture, Ain Shams University, Egypt, was to design and fabricate interior design elements to be installed within the department lobby. Students worked in digital and physical environments to develop 8 group projects that featured concept
Author(s): Abdelmohsen, Sherif M.

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General principles

In principle, online shopping is simple and involves the following stages:

  • You find a site that sells what you want (possibly using a search engine, but more frequently going to a site which you know (from personal experience, word of mouth or advertising) sells the desired goods.

  • Having found on the site, you then locate – by searching or browsing – the goods in its online catalogue.

  • You then fill in an online fo
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Acknowledgements

Except for third party materials and otherwise stated (see terms and conditions), this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence

Grateful acknowledgement is made to the following sources for permission to reproduce materia
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Keep on learning

Study another free course

There are more than 800 courses on OpenLearn for you to c
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Countries with "Free Tuition" Often Have Fewer College Graduates

Presidential candidate Elizabeth Warren says she wants to make public colleges and universities tuition-free. That is, she wants free college for anyone willing to attend a public higher education institution.

Presumably, an important goal of this policy change — other than getting Elizabeth Warren elected, of course — would be to increase the total number of students that graduate from college.

But is there any reason to believe that "free" college would actually increase g
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2.4 Applying a critical approach

A critical approach to young people's health sounds fine in the abstract, but what might it mean in practice? How can such a framework help us to make sense of young people's actual experience of physical and mental distress?

To explore these questions, we will look at the apparent increase in the incidence of eating disorders, especially among young women. One of the advantages of this example is that it combines concerns about physical and mental health. This discussion will draw on a
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Authors@Google: Justin Locke
Justin Locke, author and former bass player for the Boston Pops, visits Google Cambridge to discuss his book, "Principles of Applied Stupidity." From the book's description: "How often have you seen someone fail to move ahead in life because they were afraid of facing the unknown? How often have you seen someone endlessly seek guidance and expertise, and never actually act? The belief that we must become fully knowledgeable (and certified by others) BEFORE moving ahead is a great disincentive t
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2.6 Summary

  1. Receptors comprise a limited number of structural motifs, which determine binding affinity and specificity of receptor–ligand complexes. Some ligands bind to several receptors and some receptors bind to several ligands.

  2. Acetylcholine is a good example of a ligand with two structurally different kinds of receptor. Nicotinic receptors are ion channels, which are found predominantly in skeletal muscle, and are stimulated by nicotine. Nicotinic
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Advanced three Ball Juggling Tricks : The Claw Juggling Trick
2:25 Learn the claw juggling trick in this free juggling video. Expert: Malik Haddadi Pop and Claw Lesson flys in a triangle pattern with beanbags.
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Henry Botino
Biographie et bibliographie de l'auteur, ainsi qu'un débat sur le thème de la poésie. Lecture de poèmes: "La complainte du misérable", " le choix", "le palestinien", "à Kanaki", "O Guadeloupe", "Noël sans noël (sur la misère des enfants), "Freedom" (sur l'Afrique du Sud). "Humour, amour, poésie".
Author(s): Botino, Henry

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Crossing the Sahara Desert by Camel - Michael Palin - BBC
Michael Palin Pole-to-Pole adventure. He tries to buy a camel but has to use other methods. (03:22)
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17.1 Introduction

I'm going to pause here to try to put together some of the ideas we have encountered so far. I deliberately chose the example of a supermarket to illustrate some of the key processes involved in an ICT system. Figure 15 is a modified version of the block diagram for computers in a ne
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Human Emotion 16.2: Physical Health II (Stress)
Human Emotion; Professor June Gruber, Yale University 00:00 Chapter 1. Introduction to Lecture 00:47 Chapter 2. Stress 12.06 Chapter 3. Disease 15:40 Chapter 4. Take-Away Questions 16:10 Chapter 5. Expert Interview This course is part of a broader educational mission to share the study of human emotion beyond the boundaries of the classroom in order to reach students and teachers alike, both locally and globally, through the use of technology. This mission is generously supported by, and in
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REC100 Session 2 Fall 2011
REC100 Dimensions of Leisure Session Two 09/21/11 Mary Lou Cappel
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Higgs Boson explained with Daniel Scully
Particle Physicist Daniel Scully explains the concepts behind the elusive Higgs boson, including the methods used to look for it and what this discovery might mean for the future of mankind.
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baratocheap
bloque de pisos (el)block of flats
caroexpensive
cómodocomfortable
decorativodecorative
económicoinexpensive
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