3.1 Pre-implantation and assymetric division

Let us now return to the Fallopian tube, where a fertilized egg is assembling its chromosomes prior to commencing a series of mitotic divisions which will eventually give rise to the millions of cells that make up the human body. Obviously these millions of cells do not just exist as an amorphous mass: they are differentiated into many different types of cell, and they are organized into recognizable, discrete structures: tissues and organs. This is accomplished by a coordinated sequen
Author(s): The Open University

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6.5 Conformational changes upon protein–DNA interactions

During binding, both the protein and the DNA can alter their conformation. In the case of proteins, this conformational change can involve small changes in side-chain location, but can also involve local refolding. These changes upon binding of specific DNA sequences serve to facilitate the interaction and also to enhance the binding of other proteins, such as when dimerization of two proteins occurs at a single recognition site. Changes such as these can be the basis of cooperative binding e
Author(s): The Open University

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http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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This class examines the ways humans experience the realm of sound and how perceptions and technologies of sound emerge from cultural, economic, and historical worlds. In addition to learning about how environmental, linguistic, and musical sounds are construed cross-culturally, students learn about the rise of telephony, architectural acoustics, and sound recording, as well as about the globalized travel of these technologies. Questions of ownership, property, authorship, and copyright in the ag
Author(s): Helmreich, Stefan

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Constantin Coussios, Professor in the Institute for Biomedical Engineering at the University of Oxford, introduces the initial steps needed to launch a venture and issues to consider. In this chapter Prof. Coussios introduces concepts that will help in answering to question “Should I be an entrepreneur?”. This lecture took place at the Saïd Business School, University of Oxford on October 14th, 2014
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Author(s): Holland Ben Dr

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