6.5 Conformational changes upon protein–DNA interactions During binding, both the protein and the DNA can alter their conformation. In the case of proteins, this conformational change can involve small changes in side-chain location, but can also involve local refolding. These changes upon binding of specific DNA sequences serve to facilitate the interaction and also to enhance the binding of other proteins, such as when dimerization of two proteins occurs at a single recognition site. Changes such as these can be the basis of cooperative binding e
Eutrophication
Managing eutrophication is a key element in maintaining the earths biodiversity. Eutrophication is a process mostly associated with human activity whereby ecosystems accumulate minerals. This free course explains how this process occurs, what its effects on different types of habitat are, and how it might be managed. First published on Tue, 22 Mar 2
Plate Tectonics
Plate tectonics is an earth sciences topic that attracts a good deal of interest, given that it a topic very often featured in popular science programmes on TV and radio. It is a subject that has strong visual appeal. In this 15-hour free course the coverage is self-contained, up to date and is written in a way that will be accessible to those with interest and motivation, all the more so for those who have some pre-existing scientific understanding.
Author(s):
8.1 Introduction We have learned so far that physical energy from the environment is transduced into electrochemical messages that affect the nervous system and give rise to psychological experiences, that is, produce sensations and perceptions. Sensation refers to the initial process of detecting and encoding environmental energy. The first step in sensing the world is performed by receptor cells, which in the case of hearing are the hair cells in the cochlea. Perception on the other hand, generally refers t
CAD and Management of Construction Projects
The increasing interest in computer-aided design (CAD) has prompted research that is aimed at identifying the opportunities for construction managers and building contractors. It has been found that the use of CAD systems in the U.K. is mainly confined to the production of detailed drawings. Indeed, most of the systems used are 2-D drafting tools and incapable of supporting the integration of even modest amounts of nongraphical (construction) data. On the other hand, many 3-D modeling systems ha
Bamboo?
The presented paper discusses the combination of cutting edge technology (i.e. 3D-pinting) and raw natural grown resources (i.e. bamboo) to develop resource efficient load carrying truss structures in architectural scale. Via visual sensing the individual material properties of various bamboo poles are analyzed and directly used to inform the digital model. Comparing load carrying capacity of the bamboo pole and structural requirements of the design, the poles are placed and the connections desi
Checklist - Language Assistantship
This is a resource released as part of the E-Portfolio Toolkit based on experience of developing the “Year Abroad E-Portfolio”, undertaken by the School of Languages at Leeds Metropolitan University.
ICT en Web 2.0-tools in de taalklas : Blog Deze blog is gewijd aan interessante ICT-tools om te gebruiken in de taalklas. Wil je meer info over de gebruikte tools, dan kan je in de rechterkolom zoeken op trefwoord of termen ingeven in het zoekvak.
Rock, Paper, Scissors - Settling Classroom Disputes
I have open discussions with students about settling simple disputes. For example, we talk about when two people arrive in line at the same time, what usually happens? Sometimes an argument will start, maybe some pushing or shoving. Then we discuss other strategies to help solve the conflict fast one way is by playing "Rock, Paper, Scissor shoot". Then I show the video clip using a LCD projector. When the clip is over I pass out a card from a deck of cards and ask the kids to find a person
The History of American Literature-Poe and Hawthorne
This program that explores the work of of famous American Authors in history. In the years just before the Civil War major literary figures Poe and Hawthorne are explored along with their literary works in this clip.
The Declaration of Independence (as read by Max McLean)
The Declaration of Independence was a statement adopted by the Continental Congress on July 4, 1776, which announced that the thirteen American colonies, then at war with Great Britain, regarded themselves as independent states, and no longer a part of the British Empire. (10:20)
Implementing Mobile and e-learning in Health and Social Care
As part of a submission for the IMS Global Award, this film discusses the outputs of the ALPS CETL and demonstrates the impact that they have had on learning and assessment in practice settings, particularly focussing on the development of competency maps, 360degree multiprofessional asessment tools and the use of mobile technology to deliver these innovative assessment processes to the Health and Social Care students on placement.
Virtual Maths - Basic Structures, shear force uniformly distributed load
Interactive simulation, demonstrating shear force, uniformly distributed load
Lawrence Bailey - Market Research Valedictory Lecture
Colleagues from both academia and business were present on 27 January 2011 for Lawrence Bailey's guest lecture on Market Segmentation, Qualitative Research and Conversations Across the Garden Wall.
The garden wall of the lecture's title was Lawrence's metaphor for the potential divide between the two sectors.
The lecture reflected Lawrence's career-long wish to get qualitative researchers in the commercial world to talk to their counterparts in the academic world, and vice versa. He discusse
GesturePak v2.0 Public Beta Our second post of the Kinect MVP Carl Franklin mini-theme week we highlight a commercial project of his, which we first highlighted here, GesturePak 2.0 Alpha for the Kinect for Windows v2 Here are some of the other times we've highlighted Carl;
ISIL militants show off tank in Raqqa - amvid
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Militants loyal to the Islamic State of Iraq and the Levant, display their military strength in a parade through the province of Raqqa in eastern Syria. Natalie Thomas reports.
More from Syria: http://smarturl.it/SyriaAttack
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Reuters tells the world's stories like no one else. As the largest international multimedia news provider, Reuters provides coverage around the globe and across topics including
Thais to ponder election under martial law as way out of crisis
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May.21 - Thailand's Election Commission considers the caretaker government's proposal for an Aug. 3 election, as doubts grew that polls could be held smoothly despite the imposition of martial law to calm street violence. Sarah Toms reports.
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More Breaking News: http://smarturl.it/BreakingNews
Reuters tells the world's stories like no one else. As the largest international multimedia news provider, Re
7.013 Introductory Biology (MIT)
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organism
Russell Simmons, "Success Through Stillness: Meditation Made Simple" | Talks at Google
Master entrepreneur, original hip-hop mogul, and New York Times bestselling author Russell Simmons shares the most fundamental key to success—meditation—and guides readers to use stillness as a powerful tool to access their potential.
In the New York Times bestseller Super Rich, Russell Simmons proved that to be rich is more than just having money in the bank—wealth is about balance, joy, and conscientious living.
In Success Through Stillness, Simmons shows the connection between inner
Tommy Two Thumbs - King County Library System
In this video, a librarian recites the fingerplay "Tommy Two Thumbs".
