2.4 The covalent modification of proteins

Many proteins are modified by the covalent linking of groups that can affect their function and/or localisation in the cell. Such **covalent modifications** occur after synthesis and folding of the polypeptide component. The main types of covalent modification and their functions are listed below.

Methylation/acetylation of amino acids at the N-terminal tails of histone proteins in eukaryotes can affect the structure of chromatin and ultimately gene

8.592J Statistical Physics in Biology (MIT)

Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; considerations of force, motion, and packaging; protein motors, membranes. We also look at collective

Neutron Stars: Lighthouses of the Cosmos

Prof. Kaspi describes the astonishing properties of pulsars, as well as how observations of these amazing objects help to constrain several interesting aspects of physics of extreme environments.

1. Fourier Transforms Lecture 1

Electrical, engineering, computers, math, physics, geometry, algebra, technology, functions, applications, coding theory, signal processing, fourier series, fourier transformation, analysis, synthesis, linear operations, symmetry, frequency, velocity

3. Fourier Transforms Lecture 3

Electrical, engineering, computers, math, physics, geometry, algebra, technology, functions, linear operations, Fourier transformations, coefficients, cosin, sin, convergence, signal processing, continuos case, convergence of energy, finite energy

4. Fourier Transforms Lecture 4

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, Fourier transformations, coefficients, cos, sin, infinite sum, integrability, vector addition, application, heat fl

5. Fourier Transforms Lecture 5

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, Fourier transformations, periods, heat flow, Fourier series, convolution, non periodic, phenomena

6. Fourier Transforms Lecture 6

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, Fourier transformations, Fourier series, coefficient, limiting case, periodize, constituent parts, Fourie inversion, synthesis, sinc

7. Fourier Transforms Lecture 7

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, Fourier transformations, Fourier series, coefficient, inverse, the spectrum, signals, gaussian

8. Fourier Transforms Lecture 8

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, Fourier transformations, Fourier series, delays, stretches, convolutions, shifted, interpretations, corresponding, phase shifts, sign

9. Fourier Transforms Lecture 9

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, Fourier transformations, Fourier series, convolution, signal combinations, multiplying signals, turbidity, clarity of water, frequenc

11. Fourier Transforms Lecture 11

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, central limit theorem, repeated convolutions, random variables, CLT, convergence

12. Fourier Transforms Lecture 12

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, rapidly decreasing functions, decays, power of x, derivative, rapidly decreasing

13. Fourier Transforms Lecture 13

Electrical, engineering, computers, math, physics, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, distribution, test functions, signals, rapidly decreasing functions, generalized

15. Fourier Transforms Lecture 15

Electrical, engineering, computers, math, physics, formulas, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, deltas, diffraction, interference, light, source plane, apertures, ape

17. Fourier Transforms Lecture 17

Electrical, engineering, computers, math, physics, formulas, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, delta functions, impulse train, sampling property, periodicity propert

18. Fourier Transforms Lecture 18

Electrical, engineering, computers, math, physics, formulas, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, sampling formula, sampling proof, interpolation, band limit, periodize

19. Fourier Transforms Lecture 19

Electrical, engineering, computers, math, physics, formulas, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, spinning fan, under sample music, digital, bandwidth, music, discrete

22. Fourier Transforms Lecture 22

Electrical, engineering, computers, math, physics, formulas, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, algorithm, discrete Fourier, convolution, DFT, FFT, n*n matrix, simple

23. Fourier Transforms Lecture 23

Electrical, engineering, computers, math, physics, formulas, geometry, algebra, calculus, technology, functions, linear operations, sin, cosin, Fourier transformations, Fourier series, linear systems, impulse response, transfer function, complex exponenti