Module convenor for Research Projects. I also teach anatomy/histology/cardiorespiratory in a number of Veterinary Medicine and Science modules. I previously convened Cardiorespiratory 1.
Module convenor for three Nottingham Advantage Award modules.
Committee member and Representative of the European Association of Veterinary Anatomists.
Member of the International Committee on Veterinary Gross Anatomical Nomenclature (I.C.V.G.A.N.) working on Nomina Anatomica Veterinaria.
Wikivet trustee and OVAM collaborator.
Member of the Nottingham Recognition Scheme committee, mentoring and assessing Higher Education Academy recognition applications.
External examiner for UK Veterinary Schools.
My research areas are integrated the School of Veterinary Medicine and Research themes and concentrates on cardiovascular disorders (heart disease and angiogenesis) and anatomy.
Developmental Cardiovascular Medicine: My investigations centre around the developing cardiovascular system and include researching cardiac disorders and angiogenesis, particularly cardiomyopathies and the roles of angiogenesis related growth factors such as VEGF. One area of interest uses knock down models and information from humans to discover possible disease causing genes. In addition to investigating humans and models, my group concentrate on looking into companion animals that are suffering from cardiovascular disorders and trying to elucidate the genes that are affected/causative. This work develops prognostic tests, treatments and works towards cures for cardiovascular and angiogenesis related disorders. A number of techniques are used including molecular, cellular, histological, imaging, protein, micro CT, MRI and more recently the epigenetics of disorders are being investigated. Examples of anatomy/angiogenesis related disorders investigated in my group are lameness/footroot in horses, cattle and sheep, oncology, ocular disorders, placental and developmental biology.
My research investigates both naturally-acquired and induced diseases in many species throughout development, into adulthood and in old age. The overall aim of the work is to elucidate the molecular mechanisms behind both normal and diseased states.
Overall Aims of the Research: The work that we are undertaking will help us to better understand disorders including cardiomyopathies, musculoskeletal disorders, oncology and blindness, so that more effective diagnosis techniques, treatments and advice for patients/owners can be developed. An integrated approach to disease and development is undertaken and therefore collaborators include scientists and clinicians and a number of veterinary surgeons.
Student achievement and support:
I investigate the effects of educational and socioeconomic background, gender and nationality upon the student experience and grade achievements, using both qualitative and quantitative approaches. I have also researched student support requirements in relation to tutorial systems.
My veterinary education research revolves around developing the SVMS online veterinary museum to enable more effective learning and also includes developing teaching and museum materials. I also collaborated on the international online anatomy museum grant (OVAM) and continue to support and develop the initiative and I am a WikiVet Trustee.
Present funding: BBSRC. MRC. BHF. Academy of Medical Sciences+Wellcome Trust. AHDB. Vice-Chancellor's Scholarship for Research Excellence. Nottingham Strategic Award. Industrial awards. INSpire Award. International Collaboration Fund.
Past funding includes: BBSRC, BHF, JISC, EBLEX, Higher Education Academy, Royal Society, Petplan, Waltham Foods, Anatomical Society of Great Britain and Ireland, British Society for Developmental Biology, Talent Builder internships, Cascade Impact, Weston Scholarship, CEVA.
SIMPSON S, DUNNING MD, BROWNLIE S, PATEL J, GODDEN M, COBB M, MONGAN NP and RUTLAND CS, 2017. Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy. BioMed research international. 2016, 6374082 ENGLAND J, GRANADOS-RIVERON J, POLO-PARADA L, KURIAKOSE D, MOORE C, BROOK JD, RUTLAND CS, SETCHFIELD K, GELL C, GHOSH TK, BU'LOCK F, THORNBOROUGH C, EHLER E and LOUGHNA S, 2017. Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects. Journal of molecular and cellular cardiology. 106, 1-13
SIOBHAN SIMPSON, PAUL RUTLAND and CATRIN SIAN RUTLAND, 2017. Genomic Insights into Cardiomyopathies: A Comparative Cross-Species Review Vet. Sci.. 4(1),
Present Laboratory Members:
Aziza Alibhai - Senior researcher
Emma Lund - PhD BBSRC (Prof Mongan)
Veronika Metzler - PhD BBSRC (Profs Mongan and Heery)
Daisy Haigh - PhD BBSRC (Profs Mongan and Fray)
James Wilson - PhD AHDB (Profs Huxley and Green)
Corinne Woodcock - PhD BBSRC (Profs Mongan, Fray and Rakha)
Jennifer Lothion-Roy - PhD BBSRC (Profs Mongan and Fray)
Jemma Franklin - PhD BBSRC (Associate Profs Totemeyer, Wapenaar, Nova, Jones, Rees)
Anne Skivington, Heather Lambert, Kabilas Parameswaran - MSci
Adam Best, Kirsty Ranson, Alasdair Ross - Project Students
Zoe Skinner - Inspire research studentship.
Natasha Clarke - Clinical studentship 2019
Dr Siobhan Simpson - BBSRC
Dr Jennifer Edwards - BBSRC
Dr Matthew Parnall - BHF
Dr Ramzi Al-Agele
Dr Michael Agbaje
Dr Maria (Lola) Ruiz Diaz - Vice-Chancellor's Scholarship for Research Excellence
Heather Dunn, Francesca Hepworth, Sophie Taylor, Emily Paul (Weston Award Scholarship), Verdana Rani, Kavish Amin, Joseph Wightman, Richard Ryder.
Dr Paula Wong nee Baskeyfield, Luana Garcia dos Santos,Holly Graham - Clinical and Science without Borders internships
Gar Wai Kerry Chung - Graduate Intern and research technician
Paul (Pablo) Barrett - Graduate Intern
Mariam Saigar - Researcher and scientific writer
Claire Bordoli - Cascade E-Museum curator and research technician
Kirsty Hillier - Cascade E-Museum curator
Adeel Khan - JISC museum E-curator
Emma Cousins, Clara Bailey - 2018 Clinical EMS
Madeline Mestas, Georgia Miller, Keshia Merry - 2017 INSpire studentships
Dulcie Smith, Katie White - 2016 Clinical EMS
Matthew Keane - 2015 BBSRC studentship
Zoe Hood, Zoe Stokes - 2014 BBSRC studentship, 2015 research interns
Jenny Price, Agata Witkowska - 2013 BBSRC studentship and 2014/15 clinical research intern
Chloe Hughes - 2012 BBSRC studentship, JISC OVAM museum curator and clinical placement student.
Ammar Alibhai - 2011 BBSRC studentship, Cascade funded educational web page designer
Emilia Harding - 2010 BBSRC studentship, anatomy research/web design
Research Projects - Mark Plested, Sarah Geldart, Robin Cheung, Chloe Hughes, Agata WItkowska, Meghan Moore, Stephanie Barnett, Carolize Compton, Lauren Porteous, Thomas Mignan, Madeleine Nyberg, Hannah Partridge, Holly Graham, Janika Patel, Henry Johnson, Megan Godden, Nuria Holzleg, Elise Moritz, Matthew Keane, Rachel Woolley, Kyle Eadie, Imogen Purvis, Katie White, Dulcie Smith, Keshia Merry, Georgia Miller, Charlotte Jackman, Clara Bailey, Emma Cousins, Emily Boardman (Uni of Swansea).
Melissa Bexon, Rhys Owen, Riaz Rhemu, Lottie Back - Assisted supervision of research projects