Centre of Evidence Based Dermatology
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Systematic reviews on cellulitis 

Do you struggle to find the latest evidence about major skin disorders and their treatments? If so our maps of systematic reviews are for you.

This page is a mapping by topic of systematic reviews on cellulitis, based on searches of PubMed and other sources. Links are given to the PubMed abstract, or the original publication if not in PubMed.

Please note that this resource is about cellulitis, a potentially serious infection of the deeper layers of skin, and is not about cellulite.

It is important to appraise the quality of systematic reviews before applying to practice—we recommend the AMSTAR tool, which is very quick and easy to use.
We hope you find this resource helpful and welcome feedback.




Copyright © 2018 The University of Nottingham, on behalf of the Centre of Evidence Based Dermatology. ALL RIGHTS RESERVED.
Please reference this resource (as a web page citation) if you use it for research or publications.

Epidemiology and aetiology

Risk factors
Diagnosis & evaluation
Disease impact
Trial methodology



Prophylactic antibiotics
Surgical interventions
Treatment of predisposing factors




2020 Clinical response to antibiotic regimens in lower limb cellulitis: a systematic review

2020 Route and duration of antibiotic therapy in acute cellulitis: A systematic review and meta-analysis of the effectiveness and harms of antibiotic treatment

2019 Is coverage of S. aureus necessary in cellulitis/erysipelas? A literature review

2019 NICE guidance [NG141] Cellulitis and erysipelas: antimicrobial prescribing

2019 A state-of-the-art review highlighting medical overuse in dermatology, 2017-2018: A systematic review

2019 Tedizolid versus linezolid for the treatment of acute bacterial skin and skin structure infection: A systematic review and meta-analysis

2019 Assessment of antibiotic treatment of cellulitis and erysipelas: A systematic review and meta-analysis

2018 Group B streptococcal cellulitis and necrotizing fasciitis in infants: A systematic review

2017 Sulfamethoxazole-trimethoprim (cotrimoxazole) for skin and soft tissue infections including impetigo, cellulitis, and abscess

2016 Cellulitis: A review

2016 Failure of antibiotics in cellulitis trials: a systematic review and meta-analysis

2016 Meta-analysis of randomised trials comparing a penicillin or cephalosporin with a macrolide or lincosamide in the treatment of cellulitis or erysipelas

2016 Linezolid versus vancomycin for skin and soft tissue infections (Cochrane Review)

2014 The safety and efficacy of daptomycin versus other antibiotics for skin and soft-tissue infections: a meta-analysis of randomised controlled trials

2014 Are two penicillins better than one? A systematic review of oral flucloxacillin and penicillin V versus oral flucloxacillin alone for the emergency department treatment of cellulitis

2010 Interventions for cellulitis and erysipelas (Cochrane Review)

2010 Meta-analysis of trials evaluating parenteral antimicrobial therapy for skin and soft tissue infections

2010 Daptomycin versus other antimicrobial agents for the treatment of skin and soft tissue infections: a meta-analysis

2008 Cellulitis and erysipelas (BMJ Clinical Evidence)

2004 Once-daily cefazolin and probenecid for skin and soft tissue infections

Antibiotic plus oral corticosteroid
Vibration therapy
Chinese herbal medicine


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Orbital cellulitis

Centre of Evidence Based Dermatology

The University of Nottingham
King's Meadow Campus
Lenton Lane
Nottingham, NG7 2NR

telephone: +44 (0) 115 823 1048