Centre of Evidence Based Dermatology

Systematic reviews on cellulitis 

March 2021: This resource is now archived and no longer being updated.

We recommend the Epistemonikos database as a comprehensive, searchable database of systematic reviews. 

This page is a mapping by topic of systematic reviews on cellulitis, based on searches of PubMed and other sources. Links are given to the PubMed abstract, or the original publication if not in PubMed.




Copyright © 2021 The University of Nottingham, on behalf of the Centre of Evidence Based Dermatology. ALL RIGHTS RESERVED.
Please reference this resource (as a web page citation) if you use it for research or publications.

Epidemiology and aetiology

Risk factors
Diagnosis & evaluation
Disease impact
Trial methodology



Prophylactic antibiotics
Surgical interventions
Treatment of predisposing factors




2020 Clinical response to antibiotic regimens in lower limb cellulitis: a systematic review

2020 Route and duration of antibiotic therapy in acute cellulitis: A systematic review and meta-analysis of the effectiveness and harms of antibiotic treatment

2019 Is coverage of S. aureus necessary in cellulitis/erysipelas? A literature review

2019 NICE guidance [NG141] Cellulitis and erysipelas: antimicrobial prescribing

2019 A state-of-the-art review highlighting medical overuse in dermatology, 2017-2018: A systematic review

2019 Tedizolid versus linezolid for the treatment of acute bacterial skin and skin structure infection: A systematic review and meta-analysis

2019 Assessment of antibiotic treatment of cellulitis and erysipelas: A systematic review and meta-analysis

2018 Group B streptococcal cellulitis and necrotizing fasciitis in infants: A systematic review

2017 Sulfamethoxazole-trimethoprim (cotrimoxazole) for skin and soft tissue infections including impetigo, cellulitis, and abscess

2016 Cellulitis: A review

2016 Failure of antibiotics in cellulitis trials: a systematic review and meta-analysis

2016 Meta-analysis of randomised trials comparing a penicillin or cephalosporin with a macrolide or lincosamide in the treatment of cellulitis or erysipelas

2016 Linezolid versus vancomycin for skin and soft tissue infections (Cochrane Review)

2014 The safety and efficacy of daptomycin versus other antibiotics for skin and soft-tissue infections: a meta-analysis of randomised controlled trials

2014 Are two penicillins better than one? A systematic review of oral flucloxacillin and penicillin V versus oral flucloxacillin alone for the emergency department treatment of cellulitis

2010 Interventions for cellulitis and erysipelas (Cochrane Review)

2010 Meta-analysis of trials evaluating parenteral antimicrobial therapy for skin and soft tissue infections

2010 Daptomycin versus other antimicrobial agents for the treatment of skin and soft tissue infections: a meta-analysis

2008 Cellulitis and erysipelas (BMJ Clinical Evidence)

2004 Once-daily cefazolin and probenecid for skin and soft tissue infections

Antibiotic plus oral corticosteroid
Vibration therapy
Chinese herbal medicine


Orbital cellulitis

Orbital cellulitis

Centre of Evidence Based Dermatology

The University of Nottingham
Applied Health Research Building
University Park, Nottingham

telephone: +44 (0) 115 84 68631
email: cebd@nottingham.ac.uk