Scott Hulme

Contact

• workRoom B30 Veterinary Academic Building
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 951 6442
• fax0115 951 6440
• scott.hulme@nottingham.ac.uk

Expertise Summary

I have over 30 years of experience as a technician in a research-intensive environment, specialising in zoonotic bacteria.. My expertise spans a range of scientific disciplines, including Bacteriology, Immunology, Molecular Biology, and Histology, allowing me to contribute effectively to various aspects of research projects.

Currently, I support the Antimicrobial Resistance (AMR) research cluster within the esteemed School of Veterinary Medicine, where I collaborate with distinguished researchers and practitioners from both the School of Biosciences and the School of Veterinary Medicine. This interdisciplinary collaboration enhances our understanding of AMR and its implications for both human and animal health.

In my role, I am tasked with overseeing the calibration and functionality of specialized laboratory equipment, including microscopes, FACS machines, and key services. My team is responsible for routine checks of safety equipment, such as bio-safety cabinets, within the School of Veterinary Medicine. I ensure that all equipment operates at peak performance to meet the rigorous demands of cutting-edge research projects. My responsibilities also include providing technical advice on optimal equipment usage, troubleshooting issues, and implementing safety protocols to maintain a secure working environment.

Furthermore, I play a critical role in training staff and students on the proper usage of these technologies. I develop and conduct training sessions, workshops, and hands-on demonstrations that not only enhance their practical skills but also foster a culture of scientific inquiry and innovation. By promoting collaboration and knowledge sharing, I aim to empower the next generation of researchers to tackle the challenges posed by zoonotic diseases and antimicrobial resistance.

Recent Publications

• WIGLEY, P., HULME, S., ROTHWELL, L., BUMSTEAD, N., KAISER, P. and BARROW, P., 2006. Macrophages Isolated from Chickens Genetically Resistant or Susceptible to Systemic Salmonellosis Show Magnitudinal and Temporal Differential Expression of Cytokines and Chemokines following Salmonella enterica Challenge Infection and Immunity. VOL 74(NUMB 2), 1425-1430
• FOSTER, N., HULME, S., LOVELL, M., REED, K. and BARROW, P., 2005. Stimulation of gp91 phagocytic oxidase and reactive oxygen species in neutrophils by an avirulent Salmonella enterica serovar Infantis strain protects gnotobiotic piglets from lethal challenge with serovar Typhimurium strain F98 without inducing intestinal pathology Infection and Immunity. 73(8), 4539-4547
• WIGLEY, P., HULME, S.D., POWERS, C., BEAL, R.K., BERCHIERI, A., SMITH, A. and BARROW, P., 2005. Infection of the reproductive tract and eggs with Salmonella enterica Serovar Pullorum in the chicken is associated with suppression of cellular immunity at sexual maturity Infection and Immunity. 73(5), 2986-2990
• FOSTER, N., HULME, S. D. and BARROW, P. A., 2005. Inhibition of IFN-g-Stimulated Proinflammatory Cytokines by Vasoactive Intestinal Peptide (VIP)Correlates with Increased Survival of Salmonella enterica serovar typhimurium phoP in Murine Macrophages Journal of Interferon and Cytokine Research. VOL 25(NUMBER 1), 31-42

• View all publications

• WIGLEY, P., HULME, S., ROTHWELL, L., BUMSTEAD, N., KAISER, P. and BARROW, P., 2006. Macrophages Isolated from Chickens Genetically Resistant or Susceptible to Systemic Salmonellosis Show Magnitudinal and Temporal Differential Expression of Cytokines and Chemokines following Salmonella enterica Challenge Infection and Immunity. VOL 74(NUMB 2), 1425-1430
• FOSTER, N., HULME, S., LOVELL, M., REED, K. and BARROW, P., 2005. Stimulation of gp91 phagocytic oxidase and reactive oxygen species in neutrophils by an avirulent Salmonella enterica serovar Infantis strain protects gnotobiotic piglets from lethal challenge with serovar Typhimurium strain F98 without inducing intestinal pathology Infection and Immunity. 73(8), 4539-4547
• WIGLEY, P., HULME, S.D., POWERS, C., BEAL, R.K., BERCHIERI, A., SMITH, A. and BARROW, P., 2005. Infection of the reproductive tract and eggs with Salmonella enterica Serovar Pullorum in the chicken is associated with suppression of cellular immunity at sexual maturity Infection and Immunity. 73(5), 2986-2990
• FOSTER, N., HULME, S. D. and BARROW, P. A., 2005. Inhibition of IFN-g-Stimulated Proinflammatory Cytokines by Vasoactive Intestinal Peptide (VIP)Correlates with Increased Survival of Salmonella enterica serovar typhimurium phoP in Murine Macrophages Journal of Interferon and Cytokine Research. VOL 25(NUMBER 1), 31-42
• WIGLEY, P., HULME, S., POWERS, C., BEAL, R., SMITH, A. and BARROW, P.A., 2005. Oral infection with the Salmonella enterica serovar Gallinarum 9R attenuated live vaccine as a model to characterise immunity to fowl typhoid in the chicken. Journal of Veterinary Research. 12(1), 2
• BEAL, R. K., WIGLEY, P., POWERS, C., HULME, S. D., BARROW, P. A. and SMITH, A. L., 2004. Age at primary infection with Salmonella enterica serovar Typhimurium in the chicken influences persistence of infection and subsequent immunity to re-challenge Veterinary Immunology and Immunopathology. VOL 100(PT 3/4), 151-164
• TURNER, A.K., BARBER,L. Z., WIGLEY,P., MUHAMMAD, S., JONES, M.A., LOVELL, M.A., HULME, S. and BARROW, P.A., 2003. Contribution of proton-translocating proteins to the virulence of Salmonella enterica serovars Typhimurium, Gallinarum, and Dublin in chickens and mice Infection and Immunity. 71(6), 3392-3401
• FOSTER, N., LOVELL, M.A., MARSTON, K.L., HULME, S.D., FROST, A.J., BLAND, P. and BARROW, P.A., 2003. Rapid protection of gnotobiotic pigs against experimental salmonellosis following induction of polymorphonuclear leukocytes by avirulent Salmonella enterica Infection and Immunity. 71(4), 2182-2191
• FOSTER, N., HULME, S. D. and BARROW, P. A., 2003. Induction of Antimicrobial Pathways during Early-Phase Immune Response to Salmonella spp. in Murine Macrophages: Gamma Interferon (IFN-gamma) and Upregulation of IFN-gamma Receptor Alpha Expression Are Required for NADPH Phagocytic Oxidase gp91-Stimulated Oxidative Burst and Control of Virulent Salmonella spp Infection and Immunity. VOL 71(PART 8), 4733-4741
• WIGLEY, P., HULME, S. D., BUMSTEAD, N. and BARROW, P. A., 2002. In vivo and in vitro studies of genetic resistance to systemic salmonellosis in the chicken encoded by the SAL1 locus Microbes and Infection. VOL 4(NUMBER 11), 1111-1120
• JONES, M.A., FOSTER, N., PAGE, K., HULME, S.D. and BARROW, P.A., 2002. Salmonella enterica serovar Typhimurium F98 modulation of NO production is not host cell dependent and is inv/spa dependent. In: The International Symposium on Salmonella and Salmonellosis.. 203-204
• JONES, M.A., WIGLEY, P., PAGE, K.L., HULME, S.D. and BARROW, P.A., 2002. The role of Type-III secretion in the virulence of Salmonella enterica serovar Gallinarum and Salmonella enterica serovar Pullorum. In: International Symposium on Salmonella and Salmonellosis. 145-149
• WIGLEY, P., BUMSTEAD, N., HULME, S.D. and BARROW, P.A., 2002. Increased killing of Salmonella enterica serovar Gallinarum by macrophages from resistant inbred chicken lines. In: The International Symposium of Salmonella and Salmonellosis.. 255-256
• JONES, M. A., WIGLEY, P., PAGE, K. L., HULME, S. D. and BARROW, P. A., 2001. Salmonella enterica Serovar Gallinarum Requires the Salmonella Pathogenicity Island 2 Type III Secretion System but Not the Salmonella Pathogenicity Island 1 Type III Secretion System for Virulence in Chickens Infection and Immunity. VOL 69(PART 9), 5471-5476