Debilitating, complex and progressive, neurodegenerative disease remains an area in which new therapeutics and diagnostics are in constant – and increasing – demand.
Advanced age is the major risk factor for the most common neurodegenerative diseases, including Parkinson’s and Alzheimer’s. As many countries around the world benefit from better social provision and healthcare, people are living longer lives and the individual and societal burden of neurodegenerative disease is becoming increasingly important to address.
At The University of Nottingham our researchers are working to understand the molecular basis of neurodegeneration, using omics' technologies, together with imaging techniques to analyse the changes that occur in neurons which eventually lead to their demise. Our research team are also looking at how the cellular organelle that is central to biological energy - the mitochondrion impact ageing, lifespan and disease.
Learn more about Protein misfolding diseases
Within the Diagnostics and Therapeutics Research Group, we have a dedicated team of researchers conducting important new work into neurodegenerative conditions. They’re using a variety of approaches to determine factors that predispose degeneration.
At the same time, they’re identifying disease-specific biomarkers and molecular pathways that could be therapeutically targeted to halt or improve the symptomatic changes associated with nervous system dysfunction.
Find out more about our researchers and their work
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School of Veterinary Medicine and ScienceUniversity of NottinghamSutton Bonington Campus Leicestershire, LE12 5RD