UKRI Cross Research Council Responsive Mode Scheme
Bile duct cancer (Cholangiocarcinoma) affects 3000 people in the UK each year, with only 13% of patients surviving 3 years.
The project brings together experts in medicine, endoscopy, engineering, robotics, physics, imaging, bioelectrics and genomics to improve the accurate diagnosis and treatment of bile duct cancer.
The project will develop an ultra-slender snake-like robot technology that will be used to navigate the narrow bile duct and capture images to inform the design of a 3-D map. Stents loaded with nanoparticle will be delivered into the bile duct and activated using wireless electrical fields to stimulate the death of cancer cells.
The combined approach will create the capability to deliver treatment with greater precision with the expectation it will lead to the improved survival and quality of life for patients with CCA.
Project Lead and Co-Leads:
Guruprasad Aithal, Abdelkhalick Mohammad, Abhik Mukherjee, Alan McIntyre, Anna Grabowski, Dragos Axinte, Frankie Rawson, George Gordon, Ioan Notingher, Jane Grove, Kenton Arkill,
Kevin Gaston, Padma-Sheela Jayaraman, Xin Dong - University of Nottingham
Arvind Arora, Dhanny Gomez, Martin James, Philip Kaye and Suresh Venkatachalapathy - Nottingham University Hospitals NHS Trust
02/09/2024
Posted on Thursday 12th June 2025