GI and Liver Diseases Medical and Surgical Research
 

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Gordon Moran

Professor of Gastroenterology, Faculty of Medicine & Health Sciences

Contact

  • workRoom D1406 West Block, Queen's Medical Centre , University of Nottingham
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work+44 (0)115 9249924 ext 80608
  • fax0115 (82) 31409

Biography

Dr Moran is an academic gastroenterologist with a special interest in the clinical management of Inflammatory Bowel Disease. He has completed his gastroenterology training in Birmingham, UK and his PhD studies with Professor John Mclaughlin at the University of Manchester in 2011. He advanced his clinical training in Inflammatory Bowel disease by undertaking a one year advanced clinical fellowship in Inflammatory Bowel disease at the University of Calgary, Canada under the supervision of Professor Remo Panaccione. He has been appointed as an Associate Professor in Gastroenterology at the University of Nottingham in 2013.

Dr Moran's primary research aim is optimising advanced imaging techniques aimed at measuring inflammation and fibrosis in IBD. He leads the Simple Trials in Applied Research team within Nottingham Clinical trials Unit. The team specialises in delivering large pragmatic trials in primary care using routinely collected coded data sets. Together with collaborators at the University of Nottingham Dr Moran has created industry-funded large deeply phenotypes cohorts.

Dr Moran presently supervise 5 PhD students, 2 post-doctoral scientist and 2 IBD fellows. He is the academic and clinical IBD theme lead within the NIHR Nottingham Biomedical Research Centre and IBD Section Committee Member for the British Society of Gastroenterology and IBD expert member for the National Institute of Health Research Trent Clinical Research Network.

Dr Moran chairs the British Society of Gastroenterology Inflammatory Bowel Disease Guideline group.

Expertise Summary

Dr Moran is an academic gastroenterologist with a special interest in the clinical management of Inflammatory Bowel Disease. Dr Moran's research is focused on:

1. Large well phenotyped IBD cohorts

2. Large pragmatic clinical trials

3. Advanced Imaging

4. Mechanistic studies investigating altered physiology in Inflammatory Bowel Disease

Teaching Summary

· I teach undergraduate Year 1-3 medical students. This is small group teaching (5-7 students per rotation) focused on clinical, bed side teaching. These sessions are timetabled within the weekly… read more

Research Summary

Dr Moran is an academic gastroenterologist with a special interest in the clinical management of Inflammatory Bowel Disease. Dr Moran's research is focused on:

1. Large well phenotyped IBD cohorts

2. Large pragmatic clinical trials

3. Advanced Imaging

4. Mechanistic studies investigating altered physiology in Inflammatory Bowel Disease

Selected Publications

· I teach undergraduate Year 1-3 medical students. This is small group teaching (5-7 students per rotation) focused on clinical, bed side teaching. These sessions are timetabled within the weekly rotation for the students.

· I am an educational supervisor for core medical trainee postgraduate students.

· I deliver a modular lecture on 'Nutrition and Cancer' to the Year 1 Medical Students, BMedSci GI theme Year 2 teaching and 'Management of Inflammatory Bowel Disease and its Complications' to the Year 3 students. I have outstanding feedback.

· I am a tutor on the Nottingham Medical Imaging Anatomy and Physiology Module. I deliver a session on the medical imaging of the GI system.

· I have supervised 1 MSc (Shellie Radford 2020) and 6 PhD Students (Asseel Khalaf, 2018; Gita Thapaliya, 2019; Aly Alyami, 2020; Amanda Davies, 2020; Helen Janiszewski 2021 and Jordan McGing, 2022), 3 IBD Fellows (M Pana, 2021; K Argyriou, 2019; E Simon, 2017) to completion. Dr E Simon is now a Professor of Gastroenterology and Head of Department of Gastroenterology at the Christian Medical College, Vellore, India.

· I presently supervise 5 PhD students, 2 IBD Fellows. I am personal tutor to 6 junior medical students since 2020.

· I have been a BMedSci examiner to 3 projects with the last 2 being in 2022.

· I deliver regular teaching sessions to Specialist Gastroenterology Trainees as part of the East Midlands Training Program.

I have thoroughly improved my teaching style. My teaching sessions for Year 1 Medical students initially were focused on clinical examination. Following feedback from the medical students (see specific comments below) I adapted my sessions to address their specific request of trying to integrate the knowledge gained in their pre-clinical years with clinical problem solving. I did this by changing my lesson plan and asking the students to bring case histories to each session. Each history was de-constructed and we created interactive sessions to link pathophysiology of disease to diagnosis, treatment and management. In addition, I have incorporated different styles using role play, to make the session more dynamic. This transformed the sessions from didactic teaching to interactive tutorials. This proved to be popular with the students and has resulted in excellent feedback for the sessions. Overall, my teaching abilities have spanned all the way from bed−side teaching to being academic program director for postgraduate research in the Nottingham National Institute of Health Research Biomedical Research Centre (NIHR BRC, a research collaboration between the University of Nottingham and Nottingham University Hospitals funded through an NIHR £23.3M grant in 2022) and Translational Medical Sciences within the School of Medicine. My skills have been developed and honed down to individual necessities and large group leadership making me an excellent teacher that befits my occupation.

I have organized, funded and hosted the four Nottingham IBD Masterclass in 2014, 2015, 2017 and 2020. This is a 1-day long-industry sponsored IBD focused symposium that is aimed at practicing gastroenterology consultants, IBD nurses and senior gastroenterology trainees. The speakers are both UK-based and international with sessions focused at providing the latest evidence-based focus on common clinical problems in IBD. The attendance at the last Nottingham IBD masterclass approached 150 attendants with attendees travelling from all over the UK. The Masterclass is endorsed by the Royal College of Physicians (5 CPD points), the British Society of Gastroenterology and the NIHR Nottingham Biomedical Research Centre.

Past Research

Enteroendocrine peptides in Crohn's disease. This was the preliminary work which served as ground to initial research themes. This published work has shown an increase in tissue and postprandial plasma levels in key enteroendocrine peptides. These findings correlated to key patient symptoms.

As an Advanced IBD Fellow in Calgary, CANADA, IDr Moran completed a number of medium-large cohort studies identifying clinical biomarkers that predict patient outcomes after medical therapy.

Future Research

Future research will be focused on large pragmatic trials, well phenotyped cohorts and expanding the translational aspect of the advanced imaging portfolio of his research group.

  • DARIE, ANA-MARIA, SINOPOULOU, VASILIKI, AJAY, VERMA, BEL KOK, KLAARTJE, PATEL, KAMAL, V, LIMDI, JIMMY, AREBI, NAILA, SMITH, PHILIP, DIN, SHAHIDA, DIN, SAID, SHALE, MATTHEW, SUBRAMANIAN, SREEDHAR, PAVLIDIS, POLYCHRONIS, COONEY, RACHEL, MCGONAGLE, DENNIS, WONG, NEWTON, MORAN, GORDON W. and GORDON, MORRIS, 2023. BSG 2024 IBD guidelines protocol (standard operating procedures) BMJ OPEN GASTROENTEROLOGY. 10(1),
  • THAPALIYA, GITA, ELDEGHAIDY, SALLY, ASGHAR, MICHAEL, MCGING, JORDAN, RADFORD, SHELLIE, FRANCIS, SUSAN and MORAN, GORDON WILLIAM, 2022. The relationship between Central Nervous System morphometry changes and key symptoms in Crohn's disease BRAIN IMAGING AND BEHAVIOR.
  • GORDON, MORRIS, SINOPOULOU, VASSILIKI, AKOBENG, ANTHONY, FREEMAN, SUZANNE C., MASITARA, MASITARA, KHAN, MUHAMMAD IBRAHIM, CHERAYATH, ROSE, SHERAFAT, ALIREZA, ALQUSOUS, FAREED, ELLEITHY, ASSEM, AALI, GHAZALEH and MORAN, GORDON W., 2022. BIOLOGIC DRUGS FOR MAINTENANCE OF REMISSION IN CROHN'S DISEASE: A NETWORK META-ANALYSIS GASTROENTEROLOGY. 162(7), S233-S234
  • GORDON, MORRIS, SINOPOULOU, VASSILIKI, AALI, GHAZALEH, AKOBENG, ANTHONY, FREEMAN, SUZANNE C., MASITARA, MASITARA, KHAN, MUHAMMAD IBRAHIM, CHERAYATH, ROSE, SHERAFAT, ALIREZA, ALQUSOUS, FAREED, ELLEITHY, ASSEM and MORAN, GORDON W., 2022. BIOLOGIC DRUGS FOR INDUCTION OF REMISSION IN CROHN'S DISEASE: A NETWORK META-ANALYSIS GASTROENTEROLOGY. 162(7), S608-S609
  • RADFORD, SHELLIE J., MORAN, GORDON W. and CZUBER-DOCHAN, WLADYSLAWA, 2022. The impact of Inflammatory Bowel Disease related fatigue on Health-Related Quality of Life: a qualitative semi-structured interview study JOURNAL OF RESEARCH IN NURSING. 27(8), 685-702
  • WILHELMSEN, ANDREW, DAVIES, AMANDA, MALLINSON, JOANNE, PABLA, PARDEEP, JONES, ROBERT, PALMER, ELLIOTT A., DUNN, WARWICK B., MORAN, GORDON W., STEPHENS, FRANCIS B. and TSINTZAS, KOSTAS, 2022. Acute effects of prior dietary fat ingestion on postprandial metabolic responses to protein and carbohydrate co-ingestion in overweight and obese men: A randomised crossover trial CLINICAL NUTRITION. 41(8), 1623-1635
  • RADFORD, S., SINOPOULOU, V., GORDON, M., ELDRAGINI, M. E. A. A., DARIE, A. M., AKOBENG, A. and MORAN, G. W., 2022. Infliximab for induction of medically-induced remission in Crohn's disease: a Cochrane systematic review JOURNAL OF CROHNS & COLITIS. 16, I442-I443
  • MCGING, J., NICHOLAS, R., SERRES, S., GREENHAFF, P., FRANCIS, S. and MORAN, G. W., 2022. 31P MRS and MRI phenotyping of muscle metabolic quality in IBD fatigue JOURNAL OF CROHNS & COLITIS. 16, I171-I172
  • NAIM, I., DARIE, A. M., HOAD, C., GOWLAND, P. and MORAN, G. W., 2022. The Arborisation index: An MRI-based measure of mesenteric hyperaemia in Crohn's Disease JOURNAL OF CROHNS & COLITIS. 16, I062-I063
  • GORDON, MORRIS, SINOPOULOU, VASSILIKI, AKOBENG, ANTHONY K., PANA, MIRELA, GASIEA, REHAB and MORAN, GORDON WILLIAM, 2022. Tacrolimus (FK506) for induction of remission in corticosteroid-refractory ulcerative colitis COCHRANE DATABASE OF SYSTEMATIC REVIEWS.
  • RAINE, TIM, PAVEY, HOLLY, QIAN, WENDI, MORAN, GORDON W., SUBRAMANIAN, SREEDHAR, SWABY, LIZZIE, TRAVIS, SIMON P. L., DIN, SHAHIDA, IRVING, PETER M., LINDSAY, JAMES O., PARKES, MILES and KENNEDY, NICHOLAS A., 2022. Establishment of a validated central reading system for ileocolonoscopy in an academic setting GUT. 71(4), 661-664
  • ALEXANDER, JAMES L, MORAN, GORDON W, GAYA, DANIEL R, RAINE, TIM, HART, AILSA, KENNEDY, NICHOLAS A, LINDSAY, JAMES O, MACDONALD, JONATHAN, SEGAL, JONATHAN P, SEBASTIAN, SHAJI and OTHERS, 2021. SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement The Lancet Gastroenterology & Hepatology. 6(3), 218-224
  • ALYAMI, ALI, HOAD, CAROLINE L., TENCH, CHRISTOPHER, BANNUR, UDAY, CLARKE, CHRISTOPHER, LATIEF, KHALID, ARGYRIOU, KONSTANTINOS, LOBO, ALAN, LUNG, PHILIP, BALDWIN-CLELAND, RACHEL, SAHNAN, KAPIL, HART, AILSA, LIMDI, JIMMY K., MCLAUGHLIN, JOHN, ATKINSON, DAVID, PARKER, GEOFFREY J. M., O'CONNOR, JAMES P. B., LITTLE, ROSS A., GOWLAND, PENNY A. and MORAN, GORDON W., 2021. Quantitative Magnetic Resonance Imaging in Perianal Crohn's Disease at 1.5 and 3.0 T: A Feasibility Study DIAGNOSTICS. 11(11),
  • ALSHAMMARI, MESHARI T., STEVENSON, REBECCA, ABDUL-AEMA, BURAQ, ZOU, GUANGYONG, JAIRATH, VIPUL, RADFORD, SHELLIE, MARCIANI, LUCA and MORAN, GORDON W., 2021. Diagnostic Accuracy of Non-Invasive Imaging for Detection of Colonic Inflammation in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis DIAGNOSTICS. 11(10),
  • RADFORD, SHELLIE, CZUBER-DOCHAN, WLADYSLAWA and MORAN, GORDON W., 2021. THE IMPACT OF IBD FATIGUE ON HEALTH-RELATED QUALITY OF LIFE: A QUALITATIVE SEMI-STRUCTURED INTERVIEW STUDY GUT. 70, A113-A113
  • MCGING, JORDAN J., RADFORD, SHELLIE JEAN, FRANCIS, SUSAN T., SERRES, SEBASTIEN, GREENHAFF, PAUL L. and MORAN, GORDON W., 2021. Review article: The aetiology of fatigue in inflammatory bowel disease and potential therapeutic management strategies ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 54(4), 368-387
  • ALYAMI, ALI. S., WILLIAMS, HANNAH. G., ARGYRIOU, KONSTANTINOS, GUNN, DAVID, WILKINSON-SMITH, VICTORIA, WHITE, JONATHAN. R., ALYAMI, JABER, GOWLAND, PENNY. A., MORAN, GORDON. W. and HOAD, CAROLINE. L., 2021. Test-retest assessment of non-contrast MRI sequences to characterise and quantify the small bowel wall in healthy participants MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 34(6), 791-804
  • MORAN, GORDON WILLIAM and THAPALIYA, GITA, 2021. The Gut-Brain Axis and Its Role in Controlling Eating Behavior in Intestinal Inflammation NUTRIENTS. 13(3),
  • DAVIES, AMANDA, NIXON, ALINE, TSINTZAS, KOSTAS, STEPHENS, FRANCIS B. and MORAN, GORDON W., 2021. Skeletal muscle anabolic and insulin sensitivity responses to a mixed meal in adult patients with active Crohn's disease CLINICAL NUTRITION ESPEN. 41, 305-313
  • WHITE, JONATHAN R., DIN, SAID, INGRAM, RICHARD J. M., FOLEY, STEPHEN, ALAM, MOHAMMAD AFTAB, ROBINSON, RICHARD, FRANCIS, RODRIC, TUCKER, EMILY, JALAL, MUSTAFA, ELPHICK, DAVID, ATALLAH, EDMOND, NORMAN, ANTHONY, AMIN, MUHAMMAD, SAJJAD, AAMIR, HEGGS, NICOLA, MEADOWCROFT, SIMON and MORAN, GORDON W., 2020. Experiences of using vedolizumab in the treatment of inflammatory bowel disease in the east Midlands UK - a retrospective observational study SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 55(8), 907-916
  • KHALAF, ASSEEL, HOAD, CAROLINE L., BLACKSHAW, ELAINE, ALYAMI, JABER, SPILLER, ROBIN C., GOWLAND, PENNY A., VINAYAKA-MOORTHY, VIDHIYA, PERKINS, ALAN C., MORAN, GORDON W. and MARCIANI, LUCA, 2020. Simultaneous Measurement of Gastric Emptying of a Soup Test Meal Using MRI and Gamma Scintigraphy DIAGNOSTICS. 10(3),
  • KHALAF, ASSEEL, HOAD, CAROLINE L., MENYS, ALEX, NOWAK, ADAM, RADFORD, SHELLIE, TAYLOR, STUART A., LATIEF, KHALID, LINGAYA, MELANIE, FALCONE, YIRGA, SINGH, GULZAR, SPILLER, ROBIN C., GOWLAND, PENNY A., MARCIANI, LUCA and MORAN, GORDON W., 2020. Gastrointestinal peptides and small-bowel hypomotility are possible causes for fasting and postprandial symptoms in active Crohn's disease AMERICAN JOURNAL OF CLINICAL NUTRITION. 111(1), 131-140
  • SHIVAJI, UDAY N, SHARRATT, CAROLINE L, THOMAS, TOM, SMITH, SAMUEL CL, IACUCCI, MARIETTA, MORAN, GORDON W, GHOSH, SUBRATA and BHALA, NEERAJ, 2019. managing the adverse events caused by anti-TNF therapy in inflammatory bowel disease Alimentary pharmacology & therapeutics. 49(6), 664-680
  • WHITE, J. R., DIN, S., INGRAM, R., FOLEY, S., ALAM, M., ROBINSON, R., FRANCIS, R., TUCKER, E., JALAL, M., ELPHICK, D., ATALLAH, E., NORMAN, A., AMIN, M., SAJJAD, A., HEGGS, N., MEADOWCROFT, S. and MORAN, G. W., 2019. EXPERIENCES OF USING VEDOLIZUMAB IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE IN THE EAST MIDLANDS GUT. 68, A102-A102
  • RADFORD, SHELLIE, MCGING, JORDAN, CZUBER-DOCHAN, WLADYSLAWA and MORAN, GORDON W., 2019. THE IMPACT OF IBD RELATED FATIGUE ON HEALTH-RELATED QUALITY OF LIFE: A LITERATURE REVIEW GUT. 68, A91-A91
  • VARYANI, FUMI, ARGYRIOU, KONSTANTINOS, PHILLIPS, FRANK, TSAKIRIDOU, EIRINI and MORAN, GORDON WILLIAM, 2019. Profile of Tofacitinib in the Treatment of Ulcerative Colitis: An Evidence-Based Review of Recent Data DRUG DESIGN DEVELOPMENT AND THERAPY. 13, 4091-4104
  • SEBASTIAN, SHAJI, MYERS, SALLY, ARGYRIOU, KONSTANTINOS, MARTIN, GAYLE, LOS, LOUIS, FISKE, JOSEPH, RANJAN, RAVI, COOPER, BENJAMIN, GOODOORY, VIVEK, CHING, HEY-LONG, JAYASOORIYA, NISHANILALANTHIKA, BROOKS, JOHANNE, DHAR, ANJAN, SHENOY, ACHUT H., LIMDI, JIMMY K., BUTTERWORTH, JEFFREY, ALLEN, PATRICK B., SAMUEL, SUNIL, MORAN, GORDON W., SHENDEREY, RICHARD, PARKES, GARETH, LOBO, ALAN, KENNEDY, NICHOLAS A., SUBRAMANIAN, SREEDAR and RAINE, TIM, 2019. Infliximab induction regimens in steroid-refractory acute severe colitis: a multicentre retrospective cohort study with propensity score analysis ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 50(6), 675-683
  • WHITE, JONATHAN R., JAIRATH, VIPUL and MORAN, GORDON W., 2019. Evolution of treatment targets in Crohn's disease BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY. 38-39,
  • SEBASTIAN, SHAJI, MYERS, SALLYANN, ARGYRIOU, KONSTANTINOS, MARTIN, GAYLE, LOS, LOUIS, PATEL, NISCHELE C., GOODOORY, VIVEK, SHAIKH, FAHADALI, FISKE, JOSEPH, RANJAN, RAVI, COOPER, BENJAMIN E., CHING, HEY-LONG, JAYASOORIYA, NISHANILALANTHIKA, BROOKS, JOHANNE, ALLEN, PATRICK B., SAMUEL, SUNIL, MORAN, GORDON W., DHAR, ANJAN, LIMDI, JIMMY K., BUTTERWORTH, JEFFREY, SHENOY, ACHUTH, SHENDEREY, RICHARD, PARKES, GARETH C., LOBO, ALAN J., RAINE, TIM and SUBRAMANIAN, SREEDHAR, 2019. INFLIXIMAB INDUCTION REGIMES IN STEROID REFRACTORY ACUTE SEVERE COLITIS: A MULTICENTRE COHORT STUDY WITH PROPENSITY SCORE ANALYSIS GASTROENTEROLOGY. 156(6), S646-S646
  • SIMON, EBBY GEORGE, WARDLE, RICHARD, THI, AYE AYE, ELDRIDGE, JEANETTE, SAMUEL, SUNIL and MORAN, GORDON WILLIAM, 2019. Does fecal calprotectin equally and accurately measure disease activity in small bowel and large bowel Crohn's disease?: a systematic review INTESTINAL RESEARCH. 17(2), 160-+
  • SHIVAJI, UDAY N., SHARRATT, CAROLINE L., THOMAS, TOM, SMITH, SAMUEL C. L., IACUCCI, MARIETTA, MORAN, GORDON W., GHOSH, SUBRATA and BHALA, NEERAJ, 2019. Review article: managing the adverse events caused by anti-TNF therapy in inflammatory bowel disease ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 49(6), 664-680
  • WHITE JR, PHILLIPS F, MONAGHAN T, FATEEN W, SAMUEL S, GHOSH S and MORAN GW, 2018. Review article: novel oral-targeted therapies in inflammatory bowel disease. Alimentary pharmacology & therapeutics. 47(12), 1610-1622
  • WARDLE RA, THAPALIYA G, NOWAK A, RADFORD S, DALTON M, FINLAYSON G and MORAN GW, 2018. An Examination of Appetite and Disordered Eating in Active Crohn's Disease. Journal of Crohn's & colitis. 12(7), 819-825
  • MONAGHAN TM, ALBANESE G, KAYE P, THOMAS JD, ABERCROMBIE LC and MORAN GW, 2018. Orbital Inflammatory Complications of Crohn's Disease: A Rare Case Series. Clinical medicine insights. Gastroenterology. 11, 1179552218757512
  • KIELY CJ, CLARK A, BHATTACHARYYA J, MORAN GW, LEE JC and PARKES M, 2018. Acetarsol Suppositories: Effective Treatment for Refractory Proctitis in a Cohort of Patients with Inflammatory Bowel Disease. Digestive diseases and sciences. 63(4), 1011-1015
  • KHALAF A, NOWAK A, MENYS A, MARCIANI L, TAYLOR SA, SPILLER RC, GOWLAND PA, MORAN GW and HOAD CL, 2018. Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: Beyond the breath-hold. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. e13466 (In Press.)
  • ARGYRIOU K, SAMUEL S and MORAN GW, 2018. Acetarsol in the management of mesalazine-refractory ulcerative proctitis: a tertiary-level care experience. European journal of gastroenterology & hepatology. (In Press.)
  • WHITE, JONATHAN R, PHILLIPS, FRANK, MONAGHAN, TANYA, FATEEN, WALEED, SAMUEL, SUNIL, GHOSH, SUBRATA and MORAN, GORDON W, 2018. novel oral-targeted therapies in inflammatory bowel disease Alimentary pharmacology & therapeutics. 47(12), 1610-1622
  • SCOTT, ROBERT A., HOAD, CAROLINE, WILLIAMS, HANNAH, ORTORI, CATHERINE, MORAN, GORDON W., GOWLAND, PENNY and AITHAL, GURUPRASAD P., 2018. DEVELOPMENT OF INNOVATIVE MAGENTIC RESONANCE IMAGING METHODOLOGY TO ASSESS BOWEL PERMEABILITY GASTROENTEROLOGY. 154(6), S437-S438
  • KHALAF, A., NOWAK, A., MENYS, A., MARCIANI, L., TAYLOR, S. A., SPILLER, R. C., GOWLAND, P. A., MORAN, G. W. and HOAD, C. L., 2018. Small bowel motility of the unprepared fasted and fed small bowel: Development of a new MRI analysis technique NEUROGASTROENTEROLOGY AND MOTILITY. 30,
  • KHALAF, A., HOAD, C. L., MENYS, A., RADFORD, S., NOWAK, A., PAPARO, S., LINGAYA, M., FALCONE, Y., SINGH, G., TAYLOR, S. A., SPILLER, R. C., GOWLAND, P. A., MARCIANI, L. and MORAN, G. W., 2018. Postprandial intestinal motility and related physiology in active small-bowel Crohn's disease JOURNAL OF CROHNS & COLITIS. 12, S143-S144
  • MA, CHRISTOPHER, MORAN, GORDON W., BENCHIMOL, ERIC I., ARGOWNIK, AURA E. T., HEITMAN, STEVEN J., HUBBARD, JAMES N., SEOW, CYNTHIA H., NOVAK, KERRI L., GHOSH, SUBRATA, PANACCIONE, REMO and KAPLAN, GILAAD G., 2018. Surgical Rates for Crohn's Disease Are Decreasing: A Population-Based Time Trend Analysis and Validation Study (vol 112, pg 1840, 2017) AMERICAN JOURNAL OF GASTROENTEROLOGY. 113(2), 310-310
  • BEN-HORIN S, ANDREWS JM, KATSANOS KH, RIEDER F, STEINWURZ F, KARMIRIS K, CHEON JH, MORAN GW, CESARINI M, STONE CD, SCHWARTZ D, PROTIC M, ROBLIN X, RODA G, CHEN MH, HAR-NOY O and BERNSTEIN CN, 2017. Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis: A global survey of physicians' practice. World journal of gastroenterology. 23(16), 2995-3002
  • WARDLE RA, WARDLE AJ, CHARADVA C, GHOSH S and MORAN GW, 2017. Literature review: impacts of socioeconomic status on the risk of inflammatory bowel disease and its outcomes. European journal of gastroenterology & hepatology. 29(8), 879-884
  • CHU TPC, MORAN GW and CARD TR, 2017. The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study. Journal of Crohn's & colitis. 11(5), 578-585
  • KHALAF A, HOAD CL, MENYS A, NOWAK A, TAYLOR SA, PAPARO S, LINGAYA M, FALCONE Y, SINGH G, SPILLER RC, GOWLAND PA, MARCIANI L and MORAN GW, 2017. MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. (In Press.)
  • MA C, MORAN GW, BENCHIMOL EI, TARGOWNIK LE, HEITMAN SJ, HUBBARD JN, SEOW CH, NOVAK KL, GHOSH S, PANACCIONE R and KAPLAN GG, 2017. Corrigendum: Surgical Rates for Crohn's Disease Are Decreasing: A Population-Based Time Trend Analysis and Validation Study. The American journal of gastroenterology. 113(2), 310
  • MA C, MORAN GW, BENCHIMOL EI, TARGOWNIK LE, HEITMAN SJ, HUBBARD JN, SEOW CH, NOVAK KL, GHOSH S, PANACCIONE R and KAPLAN GG, 2017. Surgical Rates for Crohn's Disease are Decreasing: A Population-Based Time Trend Analysis and Validation Study. The American journal of gastroenterology. 112(12), 1840-1848
  • MA, CHRISTOPHER, MORAN, GORDON W, BENCHIMOL, ERIC I, TARGOWNIK, LAURA E, HEITMAN, STEVEN J, HUBBARD, JAMES N, SEOW, CYNTHIA H, NOVAK, KERRI L, GHOSH, SUBRATA, PANACCIONE, REMO and OTHERS, 2017. Surgical rates for Crohn’s disease are decreasing: a population-based time trend analysis and validation study The American journal of gastroenterology. 112(12), 1840
  • 2016. Ustekinumab: a novel therapeutic option in Crohn's disease. Expert opinion on biological therapy. (In Press.)
  • ARCHER TP, MORAN GW and GHOSH S, 2016. Tofacitinib in ulcerative colitis. Immunotherapy. 8(5), 495-502
  • SIMON EG, GHOSH S, IACUCCI M and MORAN GW, 2016. Ustekinumab for the treatment of Crohn's disease: can it find its niche? Therapeutic advances in gastroenterology. 9(1), 26-36
  • SIMON, EBBY G, GHOSH, SUBRATA, IACUCCI, MARIETTA and MORAN, GORDON W, 2016. Ustekinumab for the treatment of Crohn’s disease: can it find its niche? Therapeutic advances in gastroenterology. 9(1), 26-36
  • KAPLAN GG, LIM A, SEOW CH, MORAN GW, GHOSH S, LEUNG Y, DEBRUYN J, NGUYEN GC, HUBBARD J and PANACCIONE R, 2015. Colectomy is a risk factor for venous thromboembolism in ulcerative colitis. World journal of gastroenterology : WJG. 21(4), 1251-60
  • MORAN GW, DUBEAU MF, KAPLAN GG, YANG H, EKSTEEN B, GHOSH S and PANACCIONE R, 2015. Clinical predictors of thiopurine-related adverse events in Crohn's disease. World journal of gastroenterology. 21(25), 7795-804
  • KHALAF A, HOAD CL, SPILLER RC, GOWLAND PA, MORAN GW and MARCIANI L, 2015. Magnetic resonance imaging biomarkers of gastrointestinal motor function and fluid distribution. World journal of gastrointestinal pathophysiology. 6(4), 140-9
  • HIROTA, CHRISTINA, GASIA, MIRIAM FORT, DEANE, MAILIN, BINDRA, GURMEET K., DUBEAU, MARIE-FRANCE, MORAN, GORDON W., RABBANI, IDA, UENO, AITO, PANACCIONE, REMO, BECK, PAUL L., KAPLAN, GILAAD and GHOSH, SUBRATA, 2015. Mucosal Gene Expression Patterns From Inflamed Intestine May Distinguish Newly Diagnosed IBD From Established IBD GASTROENTEROLOGY. 148(4), S696-S696
  • HOAD, CAROLINE L., MENYS, ALEX, MARCIANI, LUCA, TAYLOR, STUART A., NOWAK, ADAM, LATIEF, KHLAID, GOWLAND, PENNY A., SPILLER, ROBIN C. and MORAN, GORDON W., 2015. Single-Visit Measures of Postprandial Pan-Intestinal Motility Using MRI Methodology: A Feasibility Study GASTROENTEROLOGY. 148(4), S668-S668
  • MORAN, G.W., DUBEAU, M.F., KAPLAN, G.G., YANG, H., SEOW, C.H., FEDORAK, R.N., DIELEMAN, L.A., BARKEMA, H.W., GHOSH, S. and PANACCIONE, R., 2014. Phenotypic features of Crohn's disease associated with failure of medical treatment Clinical Gastroenterology and Hepatology. 12(3), 434-42
  • MORAN GW and GHOSH S, 2014. Reply to Mendall. Inflammatory bowel diseases. 20(5), e13
  • MORAN GW, DUBEAU MF, KAPLAN GG, PANACCIONE R and GHOSH S, 2014. Novel concepts in inflammatory bowel disease. British medical bulletin. 109, 55-72
  • GHOSH S and MORAN GW, 2014. Letter: dermatological complications with therapy for inflammatory bowel disease--authors' reply. Alimentary pharmacology & therapeutics. 39(2), 233-4
  • MORAN GW, DUBEAU M, KAPLAN GG, PANACCIONE R and GHOSH S, 2013. The Increasing Weight of Crohn's Disease Subjects in Clinical Trials: A Hypothesis-generatings Time-trend Analysis. Inflammatory bowel diseases. (In Press.)
  • PONTOPPIDAN K, MATHEW RP and MORAN GW, 2013. Acute dysphagia after a normal endoscopy: think outside the box. Clinical medicine (London, England). 13(3), 315-6
  • MORAN GW, LAL S and MCLAUGHLIN JT, 2013. Commentary: a comparison of glucagon-like peptides 1 and 2. Alimentary pharmacology & therapeutics. 37(2), 279-80
  • MORAN GW, LESLIE FC and MCLAUGHLIN JT, 2013. Crohn's disease affecting the small bowel is associated with reduced appetite and elevated levels of circulating gut peptides. Clinical nutrition (Edinburgh, Scotland). 32(3), 404-11
  • DUBEAU M, IACUCCI M, BECK PL, MORAN GW, KAPLAN GG, GHOSH S and PANACCIONE R, 2013. Drug-induced inflammatory bowel disease and IBD-like conditions. Inflammatory bowel diseases. 19(2), 445-56
  • MORAN GW, LIM AWK, BAILEY JL, DUBEAU M, LEUNG Y, DEVLIN SM, NOVAK K, KAPLAN GG, IACUCCI M, SEOW C, MARTIN L, PANACCIONE R and GHOSH S, 2013. Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease. Alimentary pharmacology & therapeutics. 38(9), 1002-24
  • KAPLAN, G.G., SEOW, C.H., GHOSH, S., MOLODECKY, N., REZAIE, A., MORAN, G.W., PROULX, M.C., HUBBARD, J., MACLEAN, A., BUIE, D. and PANACCIONE, R., 2012. Decreasing colectomy rates for ulcerative colitis: a population-based time trend study American Journal of Gastroenterology. 107(12), 1879-1887
  • MORAN GW, O'NEILL C and MCLAUGHLIN JT, 2012. GLP-2 enhances barrier formation and attenuates TNFα-induced changes in a Caco-2 cell model of the intestinal barrier. Regulatory peptides. 178(1-3), 95-101
  • MORAN GW, O'NEILL C, PADFIELD P and MCLAUGHLIN JT, 2012. Dipeptidyl peptidase-4 expression is reduced in Crohn's disease. Regulatory peptides. 177(1-3), 40-5
  • MORAN GW, PENNOCK J and MCLAUGHLIN JT, 2012. Enteroendocrine cells in terminal ileal Crohn's disease. Journal of Crohn's & colitis. 6(9), 871-80
  • MORAN GW and BRIND A, 2012. Anaemia in a cardiopath. Gut. 61(4), 513, 581
  • DUBEAU, MARIE-FRANCE, MORAN, GORDON W., KAPLAN, GILAAD G., YANG, HONG, SEOW, CYNTHIA H., DEVLIN, SHANE, DIELEMAN, LEVINUS A., FEDORAK, RICHARD N., BARKEMA, HERMAN, GHOSH, SUBRATA and PANACCIONE, REMO, 2012. Use of Azathioprine in a Cohort of Crohn's Disease Patients on Anti-TNF Drugs and Related Surgical Outcomes GASTROENTEROLOGY. 142(5), S784-S784
  • MORAN, GORDON W., DUBEAU, MARIE-FRANCE, KAPLAN, GILAAD G., YANG, HONG, SEOW, CYNTHIA H., DEVLIN, SHANE, DIELEMAN, LEVINUS A., FEDORAK, RICHARD N., BARKEMA, HERMAN, GHOSH, SUBRATA and PANACCIONE, REMO, 2012. Fibrostenotic Disease Behavior at the Onset of Biologic Therapy is a Predictor of Poor Outcomes GASTROENTEROLOGY. 142(5), S258-S259
  • KAPLAN, GILAAD G., MORAN, GORDON W., FROLKIS, ALEXANDRA, RIOUX, KEVIN P., GHOSH, SUBRATA and PANACCIONE, REMO, 2012. Surgical Rates Have Decreased for Emergent Crohn's Disease Resections While Increasing for Elective Resections: A Population-Based Time Trend Study GASTROENTEROLOGY. 142(5), S798-S798
  • MORAN, GORDON W. and MCLAUGHLIN, JOHN, 2011. Plasma Ghrelin Paradoxically Rises Upon Feeding in Active Crohn's Disease GASTROENTEROLOGY. 140(5), S323-S323
  • MORAN, GORDON W., O'NEILL, CATHERINE A., PADFIELD, PHILIP and MCLAUGHLIN, JOHN, 2011. Dipeptidyl Peptidase IV Expression in a Cellular and Human Model of Intestinal Inflammation GASTROENTEROLOGY. 140(5), S651-S651
  • MORAN, GORDON W. and MCLAUGHLIN, JOHN, 2011. Enteroendocrine Cells and Appetite Dysregulation in Crohn's Disease GASTROENTEROLOGY. 140(5), S323-S323
  • BEN-HORIN S, MARGALIT M, BOSSUYT P, MAUL J, SHAPIRA Y, BOJIC D, CHERMESH I, AL-RIFAI A, SCHOEPFER A, BOSANI M, ALLEZ M, LAKATOS PL, BOSSA F, ESER A, STEFANELLI T, CARBONNEL F, KATSANOS K, CHECCHIN D, DE MIERA IS, REINISCH W, CHOWERS Y, MORAN GW and EUROPEAN CROHN'S AND COLITIS ORGANIZATION (ECCO), 2010. Prevalence and clinical impact of endoscopic pseudomembranes in patients with inflammatory bowel disease and Clostridium difficile infection. Journal of Crohn's & colitis. 4(2), 194-8
  • MORAN GW and MCLAUGHLIN JT, 2010. Plasma chromogranin A in patients with inflammatory bowel disease: a possible explanation. Inflammatory bowel diseases. 16(6), 914-5
  • MORAN, GORDON W. and MCLAUGHLIN, JOHN, 2010. The immune/enteroendocrine link in the regulation of food intake in intestinal disease AGRO FOOD INDUSTRY HI-TECH. 21(5), 10-12
  • MORAN GW and FISHER NC, 2009. Direct Percutaneous Endoscopic Jejunostomy: High Completion Rates with Selective Use of a Long Drainage Access Needle. Diagnostic and therapeutic endoscopy. 2009, 520879
  • BEN-HORIN, S., MARGALIT, M., BOSSUYT, P., MAUL, J., SHAPIRA, Y., BOJIC, D., CHERMESH, I., AL-RIFAI, A., SCHOEPFER, A., BOSANI, M., ALLEZ, M., LAKATOS, P.L., BOSSA, F., ESER, A., STEFANELLI, T., CARBONNEL, F., KATSANOS, K., CHECCHIN, D., MIERA, I.S. DE, CHOWERS, Y. and MORAN G.W., 2009. Combination immunomodulator and antibiotic treatment in patients with inflammatory bowel disease and clostridium difficile infection Clinical Gastroenterology and Hepatology: Official Clinical Practice Journal of the AGA Institute. 7(9), 981-987
  • MORAN GW, DILLON J and GREEN JRB, 2009. Crohn’s disease, Hepatosplenic T cell lymphoma and no Biological therapy – Are we barking up the wrong tree? Inflammatory Bowel Diseases Journal. 15(9), 1281-2
  • BEN-HORIN, SHOMRON, MARGALIT, MAYA, BOSSUYT, PETER J., MAUL, JOCHEN, SHAPIRA, YAMI, BOJIE, DANIELA, CHERMESH, IRIT, AL-RIFAI, AHMAD, SCHOEPFER, ALAIN, BOSANI, MATTEO, ALLEZ, MATTHIEU, LAKATOS, PETER L., BOSSA, FABRIZIO, ESER, ALEXANDER, STEFANELLI, TOMMASO, CARBONNEL, FRANCK, KATSANOS, KONSTANTINOS, CHECCHIN, DAVIDE, DE MIERA, INES SAENZ, CHOWERS, YEHUDA and MORAN, GORDON W., 2009. The Impact of Concomitant Treatment with Immuno-Modulators and Antibiotics On the Outcome of C-difficile-Associated Inflammatory Bowel Disease Exacerbation: A European Multi-Center Retrospective Study GASTROENTEROLOGY. 136(5), A652-A652
  • MAHIDA YR and MORAN GW, 2008. Do non-immune cells have a role in IBD? Inflammatory bowel diseases. 14 Suppl 2, S123-4
  • MORAN GW and FISHER NC, 2008. Myelofibrosis, splenomegaly, and upper gastrointestinal hemorrhage: an unusual link. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 6(9), xxiv
  • MORAN GW, LESLIE FC, LEVISON SE, WORTHINGTON J and MCLAUGHLIN JT, 2008. Enteroendocrine cells: neglected players in gastrointestinal disorders? Therapeutic advances in gastroenterology. 1(1), 51-60
  • MORAN GW, HEJMADI R, CAMPBELL E and BOULTON R, 2008. Ulcers and the colon: keep an open mind. Gut. 57(9), 1221, 1267
  • MORAN, G. W., NIZAM, S., ANGIT, C. and GREEN, J. R. B., 2008. Another nail in the coffin for barium enema? GUT. 57, A164-A165
  • MORAN, G. W., CHERIAN, S., DESILVA, S., ROBERTS, G., GILL, M., TANIERE, P., BOULTON, R. and GOH, J., 2008. Superinfection in inflammatory bowel disease: Does it really matter? GUT. 57, A141-A142
  • MORAN, GORDON W, LESLIE, FIONA C, LEVISON, SCOTT E and MCLAUGHLIN, JOHN T, 2008. Enteroendocrine cells: neglected players in gastrointestinal disorders? Therapeutic advances in gastroenterology. 1(1), 51-60
  • MORAN, G. W. and FISHER, N. C., 2007. Direct percutaneous endoscopic jejunostomy: Technique and a five-year review GUT. 56, A96-A96
  • MORAN, G. W., STONE, T., WOLINSKI, A., PATEL, R. and JONES, B. J. M., 2007. From phlebolith to surgery GUT. 56, A36-A36
  • MORAN GW, SMITH MSH and BUTTERWORTH JR, 2006. Gastrointestinal bleeding: don't overlook the role of the pancreas. Gut. 55(1), 104, 113
  • MORAN, GW and JONES, BJM, 2006. Why every trust practicing parenteral nutrition should have a nutrition team GUT. 55, A13-A13
  • COCHRANE GUT GROUP, GORDON, MORRIS, SINOPOULOU, VASSILIKI, AKOBENG, ANTHONY K, PANA, MIRELA, GASIEA, REHAB and MORAN, GORDON WILLIAM, 1996. Tacrolimus (FK506) for induction of remission in corticosteroid-refractory ulcerative colitis Cochrane Database of Systematic Reviews. 2022(4),

Nottingham Digestive Diseases Centre

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