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HAMED MR, BROWN RJP, ZOTHNER C, URBANOWICZ RA, MASON CP, KRARUP A, MCCLURE CP, IRVING WL, BALL JK, HARRIS M, HICKLING TP and TARR AW, 2014. Recombinant human L-ficolin directly neutralizes hepatitis C virus entry. Journal of innate immunity. 6(5), 676-84 MEOLA A, TARR AW, ENGLAND P, MEREDITH LW, MCCLURE CP, FOUNG SKH, MCKEATING JA, BALL JK, REY FA and KREY T, 2014. Structural Flexibility of a Conserved Broadly Neutralizing Epitope in Hepatitis C Virus Glycoprotein E2. Journal of virology. (In Press.)
LACEK K, URBANOWICZ RA, TROISE F, DE LORENZO C, SEVERINO V, DI MARO A, TARR AW, FERRARA F, PLOSS A, TEMPERTON N, BALL JK, NICOSIA A, CORTESE R and PESSI A, 2014. Dramatic Potentiation of the Antiviral Activity of HIV Antibodies by Cholesterol Conjugation. The Journal of biological chemistry. 289(50), 35015-28 HAMED MR,, BROWN RJ, ZOTHNER C, URBANOWICZ RA, MASON CP, KRARUP A, MCCLURE CP, IRVING WL, BALL JK HARRIS M, HICKLING TP and TARR AW, 2014. Recombinant human L-ficoin directly neutralizes hepatitis C virus entry. Journal of Innate Immunity. 6, 676-684 NG, PATRICK P., KUO, CHIUNG-CHI, WANG, STANLEY, EINAV, SHIRIT, ARCAINI, LUCA, PAULLI, MARCO, PORTLOCK, CAROL S., MARCOTRIGIANO, JOSEPH, TARR, ALEXANDER, BALL, JONATHAN, LEVY, RONALD and LEVY, SHOSHANA, 2014. B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)-infected patients rarely react with the viral proteins BLOOD. 123(10), 1512-1515 KIM, YOUNG CHAN, TARR, ALEXANDER W. and PENFOLD, CHRISTOPHER N., 2014. Colicin import into E. coli cells: A model system for insights into the import mechanisms of bacteriocins BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 1843(8), 1717-1731 BROWN, RICHARD J. P., KOUTSOUDAKIS, GEORGE, URBANOWICZ, RICHARD A., MIRZA, DEEMAN, GINKEL, CORINNE, RIEBESEHL, NINA, CALLAND, NOEMIE, ALBECKA, ANNA, PRICE, LOUISA, HUDSON, NATALIA, DESCAMPS, VERONIQUE, BACKX, MATTHIJS, MCCLURE, C. PATRICK, DUVERLIE, GILLES, PECHEUR, EVE-ISABELLE, DUBUISSON, JEAN, PEREZ-DEL-PULGAR, SOFIA, FORNS, XAVIER, STEINMANN, EIKE, TARR, ALEXANDER W., PIETSCHMANN, THOMAS and BALL, JONATHAN K., 2014. Analysis of Serine Codon Conservation Reveals Diverse Phenotypic Constraints on Hepatitis C Virus Glycoprotein Evolution JOURNAL OF VIROLOGY. 88(1), 667-678 SAUTTO, GIUSEPPE, TARR, ALEXANDER W., MANCINI, NICASIO and CLEMENTI, ANDMASSIMO, 2013. Structural and Antigenic Definition of Hepatitis C Virus E2 Glycoprotein Epitopes Targeted by Monoclonal Antibodies CLINICAL & DEVELOPMENTAL IMMUNOLOGY.
BROWN, R.J.P., KOUTSOUDAKIS, G., URBANOWICZ, R.A., MIRZA, D., GINKEL, C., RIEBESEHL, N., CALLAND, N., ALBECKA, A., PRICE, L., HUDSON, N., DESCAMPS, V., BACKX, M., MCCLURE, C.P., DUVERLIE, G., PECHEUR, E., DUBUISSON, J., PEREZ-DEL-PULGAR, S., FORNS, X., STEINMANN, E., TARR, A.W., PIETSCHMANN, T. and BALL, J.K., 2013. Analysis of serine codon conservation reveals diverse phenotypic constraints on Hepatitis C Virus glycoprotein evolution Journal of Virology. n/a(n/a), n/a TARR, A.W., LAFAYE, P., MEREDITH, L., DAMIER-PIOLLE, L., URBANOWICZ, R.A., MEOLA, A., JESTIN, J.-L., BROWN, R.J.P., MCKEATING, J.A., REY, F.A., BALL, J.K. and KREY, T., 2013. An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission Hepatology. 58(3), 932-939 EDWARDS VC, TARR AW, URBANOWICZ RA and BALL JK, 2012. The role of neutralizing antibodies in hepatitis C virus infection. The Journal of general virology. 93(Pt 1), 1-19 TARR, A.W., URBANOWICZ, R.A., JAYARAJ, D., BROWN, R.J.P., MCKEATING, J.A., IRVING, W.L. and BALL, J.K., 2012. Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization Journal of Virology. 86(5), 2739-2749 ALBECKA, A., MONTSERRET, R., KREY, T., TARR, A.W., DIESIS, E., BALL, J.K., DESCAMPS, V., DUVERLIE, G., REY, F., PENIN, F. and DUBUISSON, J., 2011. Identification of new functional regions in hepatitis C virus envelope glycoprotein E2 Journal of Virology. 85(4), 1777-1792 TARR, A.W., URBANOWICZ, R.A., HAMED, M.R., ALBECKA, A., MCCLURE, C.P., BROWN, R.J.P., IRVING, W.L., DUBUISSON, J. and BALL, J.K., 2011. Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype Journal of Virology. 85(9), 4246-4257 BROWN, K.S., KEOGH, M.J., OWSIANKA, A.M., ADAIR, R., PATEL, A.H., ARNOLD, J.N., BALL, J.K., SIM, R.B., TARR, A.W. and HICKLING, T.P., 2010. Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry Protein & Cell. 1(7), 664-674 HAMED, M.R.B., TARR, A.W., MCCLURE, C.P., BALL, J.K., HICKLING, T.P. and IRVING, W.L., 2008. Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease Journal of Viral Hepatitis. 15(5), 339-345 OWSIANKA, ANIA M, TARR, ALEXANDER W, KECK, ZHEN-YONG, LI, TA-KAI, WITTEVELDT, JEROEN, ADAIR, RICHARD, FOUNG, STEVEN K H, BALL, JONATHAN K and PATEL, ARVIND H, 2008. Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein. Journal of General Virology. 89(Pt 3), 653-9
OWSIANKA, A, TARR, AW, KECK, Z-Y, LI, T-K, WITTEVELDT, J, ADAIR, R, FOUNG, S.K and BALL, J.K. & PATEL, A.H., 2008. Broadly neutralizing human antibodies to the hepatitis C virus E2 glycoprotein Journal of General Virology. 89, 653-659 PEROTTI, M., MANCINI, N., DIOTTI, R.A., TARR, A.W., BALL, J.K., OWSIANKA, A., ADAIR, R., PATEL, A.H., CLEMENTI, M. and BURIONI, R., 2008. Identification of a broadly cross-reacting and neutralizing human monoclonal antibody directed against the hepatitis C virus E2 protein Journal of Virology. 82(2), 1047-1052 LAW, M., MARUYAMA, T., LEWIS, J., GIANG, E., TARR, A.W., STAMATAKI, Z., GASTAMINZA, P., CHISARI, F.V., JONES, I.M., FOX, R.I., BALL, J.K., MCKEATING, J.A., KNETEMAN, N.M. and BURTON, D.R., 2008. Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge Nature Medicine. 14(1), 25-27 TARR, ALEXANDER W, OWSIANKA, ANIA M, JAYARAJ, DHANYA, BROWN, RICHARD J P, HICKLING, TIMOTHY P, IRVING, WILLIAM L, PATEL, ARVIND H and BALL, JONATHAN K, 2007. Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33. Journal of General Virology. 88(Pt 11), 2991-3001
LAW,, MARUYAMA,, LEWIS,, GIANG,, TARR,, STAMATAKI,, GASTAMINZA,, CHISARI,, JONES,, FOX,, BALL,, MCKEATING,, KNETEMAN, and BURTON,, 2007. Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nature Medicine. TARR, ALEXANDER W, OWSIANKA, ANIA M, SZWEJK, ALEXANDRA, BALL, JONATHAN K and PATEL, ARVIND H, 2007. Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins. Methods in Molecular Biology. 379, 177-97
JOHANSSON, DANIEL X, VOISSET, CÉCILE, TARR, ALEXANDER W, AUNG, MIE, BALL, JONATHAN K, DUBUISSON, JEAN and PERSSON, MATS A A, 2007. Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 104(41), 16269-74 TARR, A.W, OWSIANKA, A.M, SZWEJK, A and BALL, J.K. & PATEL, A.H., 2007. Cloning, expression and functional analysis of patient-derrived hepatitis C virus glycoproteins. In: SUGRUE, R.J., ed., Glycovirology Protocols Humana Press. 177-198
TARR, A.W., OWSIANKA, A.M., TIMMS, J.M., MCCLURE, C.P., BROWN, R.J.P., HICKLING, T.P., PIETSCHMANN, T., BARTENSCHLAGER, R., PATEL, A.H. and BALL, J.K., 2006. Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33. Hepatology (Baltimore, Md.). 43(3), 592-601 OWSIANKA, A.M, TIMMS, J.M., TARR, A.W., BROWN, R.J.P., HICKLING, T.P., SZWEJK, A., BIENKOWSKA-SZEWCZYK, K., THOMSON, B.J., PATEL, A.H. and BALL, J.K., 2006. Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding. Journal of Virology. 80(17), 8695-8704 BROWN RJP, JUTTLA VS, FINNIS R, TARR AW, HEMSLEY S, FLOWER DR, BORROW P, IRVING WL, BALL JK., 2005. Evolutionary dynamics of Hepatitis C virus envelope genes during chronic infection. Journal of General Virology. 86, 1931-1942 OWSIANKA, A., TARR, A.W., JUTTLA, V.S., LAVILLETTE, D., BARTOSCH, B., COSSET, F.-L., BALL, J.K. and PATEL, A.H., 2005. Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein Journal of Virology. 79(17), 11095-11104 YAMADA, E., MONTOYA, M., SCHUETTLER, C.G., HICKLING, T.P., TARR, A.W., VITELLI, A., DUBUISSON, J., PATEL, A.H., BALL, J.K. and BORROW, P., 2005. Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets. Journal of General Virology. 86(9), 2507-2512 LAVILLETTE, D., TARR, A.W., VOISSET, C., DONOT, P., BARTOSCH, B., BAIN, C., PATEL, A.H., DUBUISSON, J., BALL, J.K. and COSSET, F.-L., 2005. Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus. Hepatology (Baltimore, Md.). 41(2), 265-274 TARR, A. W., BONEHAM, S. P., GRABOWSKA, A. M. and BALL, J. K., 2005. Tagged polymerase chain reaction subtractive hybridization for the enrichment of phage display random peptide libraries Analytical Biochemistry. VOL 339(NUMBER 1), 61-68 BROWN, RICHARD J. P., HUDSON, NATALIA, WILSON, GARRICK, REHMAN, SHAFIQ UR, JABBARI, SARA, HU, KE, TARR, ALEXANDER W., BORROW, PERSEPHONE, JOYCE, MICHAEL, LEWIS, JAMIE, ZHU, LIN FU, LAW, MANSUN, KNETEMAN, NORMAN, TYRRELL, D. LORNE, MCKEATING, JANE A. and BALL, JONATHAN K., Hepatitis C Virus Envelope Glycoprotein Fitness Defines Virus Population Composition following Transmission to a New Host JOURNAL OF VIROLOGY. 86(22), 11956-11966