Osteoarthritis and Crystal Arthritis
 

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Ana Valdes

Professor, Faculty of Medicine & Health Sciences

Contact

  • workRoom A28, Academic Rheumatology Clinical Sciences Building
    Nottingham City Hospital
    Hucknall Road
    Nottingham
    NG5 1PB
    UK
  • work0115 823 1954
  • fax0115 823 1757

Biography

Ana M. Valdes received her M.A. and Ph.D. from the University of California at Berkeley, USA, where she specialized in Genetic Epidemiology. She is Professor of Molecular and Genetic Epidemiology at the School of Medicine in the University of Nottingham. Her research is focused on deciphering the molecular mechanisms related to ageing and age related diseases such as osteoarthritis and cardiovascular disease and on the role of gut microbiome composition on human health. With Prof Olliverer set up a cohort of healthcare workers during the Covid-19 pandemic pantherstudy.org.uk which is currently following the antibody responses of healthcare workers to vaccination

Expertise Summary

Metabolomics

Gut microbiome

metabolic syndrome

nutrition

Research Summary

Covid-19 research: co-Chief Investigator of the Pandemic Tracking of Healthcare Workers (www.pantherstudy.org.uk) tracking seropositivity and trasmission of SARS-CoV-2 in healthcare… read more

Selected Publications

Current Research

  1. Covid-19 research: co-Chief Investigator of the Pandemic Tracking of Healthcare Workers (www.pantherstudy.org.uk) tracking seropositivity and trasmission of SARS-CoV-2 in healthcare workers
  2. Inflammation, nutrition, metabolic syndrome and the gut microbiome. In collaboration with the Dept of Twin Research I have carried extensive work on the metabolomic profiles of obesity and visceral fat, the metabolomic signatures of weight loss and the role of the gut microbiome on weight loss and visceral fat. I have also investigated nutritional contributions to the gut microbiome. This work has received considerable media attention and I have helped to disseminate this work via The Conversation. I am also a consultant for Industry seeking to develop personalised approaches to nutrition based on gut microbiome charactersitics.
  3. Genetics and molecular basis of osteoarthritis (OA): I am Research Area Lead within the Nottingham NIHR BRC muscoloskeletal theme and a Co-I in the the Versus Arthritis Pain Centre. I have recently published GWAS, biomarkers genetic association studies on the molecular basis of OA pain and neuropathic pain post total joint replacement, in addition to several biomarker related studies on OA
  4. Molecular basis of aging and cardiovascular disease. I have co-authored several papers in this area including my work on the role of mitochondrial heteroplasmy on ageing and of telomeres as markers of biological aging I am currently co-investigator in the MRC stratified medicine consortium for hypertension AIM-HY and have published several articles on biormarkers of cardiovascular disease in the top Cardiology journals

Academic Rheumatology

The University of Nottingham
School of Medicine
Clinical Sciences Building
Nottingham, NG5 1PB


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