Research Fellow, Faculty of Medicine & Health Sciences
I completed my undergraduate degree in Neuroscience at the University of Nottingham, and went on to undertake doctoral studies on in Victoria Chapman's lab, utilising behavioural, electrophysiological, and molecular biological approaches to study the role of the spinal cannabinoid and vanillloid systems in models of acute and chronic pain. I subsequently spent 5 years in Budapest, Hungary, conducting post-doctoral research on the anatomy of the spinal endocannabinoid system in Istvan Katona's lab at the Institute of Experimental Medicine. During this time I acquired expertise in immunohistochemical techniques including STORM super-resolution imaging. Since returning to Professor Chapman's lab, I have established the application of STORM imaging to quantify nanoscale anatomical correlates of pain in neural tissue in Nottingham. Recent work combines anatomical and physiological techniques to reveal insights into spinal mechanisms of pain, including investigating the link between anxiety, opioids and OA pain in a translationally-relevant preclinical model, and studying the effects of healthy aging on spinal sensory network function.
In vivo rodent pain models (inflammatory, osteoarthritis), in vivo spinal electrophysiology, ELISAs, Western blotting and enzyme activity assays, immunohistochemistry (DAB, fluorescence, electron microscopy) & STORM super-resolution imaging.
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