Centre for Evidence Based Hand Surgery
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Anaesthesia & analgesia




Guidelines for the Provision of Anaesthesia Services for Trauma and Orthopaedic Surgery 2019.
Royal College of Anaesthetists.
London: Royal College of Anaesthetists, 2019.

Guidelines for the Provision of Anaesthesia Services for Burn and Plastics Surgery 2019.
Royal College of Anaesthetists.
London: Royal College of Anaesthetists, 2019.

Brachial plexus & peripheral nerve blocks

Dexamethasone as an adjuvant to peripheral nerve block.
Pehora C, Pearson AM, Kaushal A, Crawford MW, Johnston B.
Cochrane Database Syst Rev. 2017 Nov 9;11:CD011770. doi: 10.1002/14651858.CD011770.pub2.

Single, double or multiple-injection techniques for non-ultrasound guided axillary brachial plexus block in adults undergoing surgery of the lower arm.
Chin KJ, Cubillos JE, Alakkad H.
Cochrane Database Syst Rev. 2016 Sep 2;9:CD003842. DOI: 10.1002/14651858.CD003842.pub5.

Local anaesthetic sympathetic blockade for complex regional pain syndrome.
O'Connell NE, Wand BM, Gibson W, Carr DB, Birklein F, Stanton TR.
Cochrane Database Syst Rev. 2016 Jul 28;7:CD004598. doi: 10.1002/14651858.CD004598.pub4.

Ultrasound guidance for upper and lower limb blocks.
Lewis SR, Price A, Walker KJ, McGrattan K, Smith AF.
Cochrane Database Syst Rev. 2015 Sep 11;9:CD006459. doi: 10.1002/14651858.CD006459.pub3.

Adrenaline with lidocaine for digital nerve blocks.
Prabhakar H, Rath S, Kalaivani M, Bhanderi N.
Cochrane Database Syst Rev. 2015 Mar 19;3:CD010645. doi: 10.1002/14651858.CD010645.pub2.

Infraclavicular brachial plexus block for regional anaesthesia of the lower arm.
Chin KJ, Alakkad H, Adhikary SD, Singh M.
Cochrane Database Syst Rev. 2013 Aug 28;8:CD005487.doi: 10.1002/14651858.CD005487.pub3.

Anaesthesia for treating distal radial fracture in adults.
Handoll HH, Madhok R, Dodds C.
Cochrane Database Syst Rev. 2002;(3):CD003320.

The effect and safety of dexmedetomidine added to ropivacaine in brachial plexus block: A meta-analysis of randomized controlled trials.
Dai W, Tang M, He K.
Medicine (Baltimore). 2018 Oct;97(41):e12573. doi: 10.1097/MD.0000000000012573.

Dexamethasone is superior to dexmedetomidine as a perineural adjunct for supraclavicular brachial plexus block: Systematic review and indirect meta-analysis.
Albrecht E, Vorobeichik L, Jacot-Guillarmod A, Fournier N, Abdallah FW.
Anesth Analg. 2019 Mar;128(3):543-554. doi: 10.1213/ANE.0000000000003860.

The analgesic efficacy of intravenous regional anesthesia with a forearm versus conventional upper arm tourniquet: a systematic review.
Dekoninck V, Hoydonckx Y, Van de Velde M, Ory JP, Dubois J, Jamaer L, Jalil H, Stessel B.
BMC Anesthesiol. 2018 Jul 18;18(1):86. doi: 10.1186/s12871-018-0550-4.

Anaesthesia for open wrist fracture surgery in adults/elderly.
Sellbrandt I, Brattwall M, Warrén Stomberg M, Jildenstål P, Jakobsson JG.
F1000Res. 2017 Nov 13;6:1996. doi: 10.12688/f1000research.13004.1. eCollection 2017.

Effect of tramadol as an adjuvant to local anesthetics for brachial plexus block: A systematic review and meta-analysis.
Shin HW, Ju BJ, Jang YK, You HS, Kang H, Park JY.
PLoS One. 2017 Sep 27;12(9):e0184649. doi: 10.1371/journal.pone.0184649. eCollection 2017.

Optimal dose of perineural dexamethasone to prolong analgesia after brachial plexus blockade: A systematic review and meta-analysis.
Kirkham KR, Jacot-Guillarmod A, Albrecht E.
Anesth Analg. 2018 Jan;126(1):270-279. doi: 10.1213/ANE.0000000000002488.

Comparison of supraclavicular and infraclavicular brachial plexus block: A systemic review of randomized controlled trials.
Park SK, Lee SY, Kim WH, Park HS, Lim YJ, Bahk JH.
Anesth Analg. 2017 Feb;124(2):636-644. doi: 10.1213/ANE.0000000000001713.

Perineural dexmedetomidine is more effective than clonidine when added to local anesthetic for supraclavicular brachial plexus block: a systematic review and meta-analysis.
El-Boghdadly K, Brull R, Sehmbi H, Abdallah FW.
Anesth Analg. 2017 Jun;124(6):2008-2020. doi: 10.1213/ANE.0000000000002014.

Investigating the efficacy of dexmedetomidine as an adjuvant to local anesthesia in brachial plexus block: A systematic review and meta-analysis of 18 randomized controlled trials.
Hussain N, Grzywacz VP, Ferreri CA, Atrey A, Banfield L, Shaparin N, Vydyanathan A.
Reg Anesth Pain Med. 2017 Mar/Apr;42(2):184-196. doi: 10.1097/AAP.0000000000000564.

Evidence basis for using perineural dexmedetomidine to enhance the quality of brachial plexus nerve blocks: a systematic review and meta-analysis of randomized controlled trials.
Vorobeichik L, Brull R, Abdallah FW.
Br J Anaesth. 2017 Feb;118(2):167-181. doi: 10.1093/bja/aew411.

Dexmedetomidine as an adjuvant to local anesthetics in brachial plexus blocks: A meta-analysis of randomized controlled trials.
Ping Y, Ye Q, Wang W, Ye P, You Z.
Medicine (Baltimore). 2017 Jan;96(4):e5846. doi: 10.1097/MD.0000000000005846.

Can we use lower volume of local anesthetic for infraclavicular brachial plexus nerve block under ultrasound guidance in children?
Ince I, Aksoy M, Dostbil A, Tuncer K.
J Clin Anesth. 2017 Sep;41:132-136. doi: 10.1016/j.jclinane.2016.12.017. Epub 2017 Jan 9.

Ultrasound guidance improves the success rate of axillary plexus block: a meta-analysis.
Qin Q, Yang D, Xie H, Zhang L, Wang C.
Braz J Anesthesiol. 2016 Mar-Apr;66(2):115-9. doi: 10.1016/j.bjane.2015.01.002. Epub 2015 Oct 1.

Evidence base for the use of ultrasound for upper extremity blocks: 2014 update.
Choi S, McCartney CJ.
Reg Anesth Pain Med. 2016 Mar-Apr;41(2):242-50. doi: 10.1097/AAP.0000000000000155.

Evidence basis for ultrasound-guided block characteristics onset, quality, and duration.
Liu SS.
Reg Anesth Pain Med. 2016 Mar-Apr;41(2):205-20. doi: 10.1097/AAP.0000000000000141.

A systematic review of ultrasound-guided methods for brachial plexus blockade.
Albrecht E, Mermoud J, Fournier N, Kern C, Kirkham KR.
Anaesthesia. 2016 Feb;71(2):213-27. doi: 10.1111/anae.13347. Epub 2015 Dec 16.

Combination of dexamethasone and local anaesthetic solution in peripheral nerve blocks: A meta-analysis of randomised controlled trials.
Huynh TM, Marret E, Bonnet F.
Eur J Anaesthesiol. 2015 Nov;32(11):751-8. doi: 10.1097/EJA.0000000000000248.

[Bilateral brachial plexus block. Case report and systematic review].
Mejia-Terrazas GE, Garduño-Juárez Mde Á, Limón-Muñoz M, Torres-Maldonado AS, Carrillo-Esper R.
Cir Cir. 2015 Jul-Aug;83(4):312-8. doi: 10.1016/j.circir.2015.05.018. Epub 2015 Jun 25. Spanish.

Perineural dexamethasone added to local anesthesia for brachial plexus block improves pain but delays block onset and motor blockade recovery.
Knezevic NN, Anantamongkol U, Candido KD.
Pain Physician. 2015 Jan-Feb;18(1):1-14.

Perineural dexamethasone to improve postoperative analgesia with peripheral nerve blocks: a meta-analysis of randomized controlled trials.
De Oliveira GS Jr, Castro Alves LJ, Nader A, Kendall MC, Rahangdale R, McCarthy RJ.
Pain Res Treat. 2014;2014:179029. doi: 10.1155/2014/179029. Epub 2014 Nov 18.

Comparison of local anesthetics for digital nerve blocks: a systematic review.
Vinycomb TI, Sahhar LJ.
J Hand Surg Am. 2014 Apr;39(4):744-751.e5. doi: 10.1016/j.jhsa.2014.01.017. Epub 2014 Mar 5.

Effects of dexamethasone as a local anaesthetic adjuvant for brachial plexus block: a systematic review and meta-analysis of randomized trials.
Choi S, Rodseth R, McCartney CJ.
Br J Anaesth. 2014 Mar;112(3):427-39. doi: 10.1093/bja/aet417. Epub 2014 Jan 10.

Facilitatory effects of perineural dexmedetomidine on neuraxial and peripheral nerve block: a systematic review and meta-analysis.
Abdallah FW, Brull R.
Br J Anaesth. 2013 Jun;110(6):915-25. doi: 10.1093/bja/aet066. Epub 2013 Apr 15.

Analgesic efficacy of ultrasound-guided regional anesthesia: a meta-analysis.
Gelfand HJ, Ouanes JP, Lesley MR, Ko PS, Murphy JD, Sumida SM, Isaac GR, Kumar K, Wu CL.
J Clin Anesth. 2011 Mar;23(2):90-6. doi: 10.1016/j.jclinane.2010.12.005.


Upper-extremity nerve decompression under local anesthesia: A systematic review of methods for reduction of postoperative pain and opioid consumption.
Chocron Y, Aljerian A, Thibaudeau S.
Hand (N Y). 2019 Apr 15:1558944719843635. doi: 10.1177/1558944719843635. [Epub ahead of print]

Review article: Best practice management of closed hand and wrist injuries in the emergency department (part 5 of the musculoskeletal injuries rapid review series).
Strudwick K, McPhee M, Bell A, Martin-Khan M, Russell T.
Emerg Med Australas. 2018 May 24. doi: 10.1111/1742-6723.12969. [Epub ahead of print]

Management of acute postoperative pain in hand surgery: a systematic review.
Kelley BP, Shauver MJ, Chung KC.
J Hand Surg Am. 2015 Aug;40(8):1610-9, 1619.e1. doi: 10.1016/j.jhsa.2015.05.024.

Interventions for neuropathic pain: An overview of systematic reviews.
Dosenovic S, Jelicic Kadic A, Miljanovic M, Biocic M, Boric K, Cavar M, Markovina N, Vucic K, Puljak L.
Anesth Analg. 2017 Aug;125(2):643-652. doi: 10.1213/ANE.0000000000001998.




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Centre for Evidence Based Hand Surgery

The University of Nottingham
C Floor, West Block, QMC
Nottingham, NG7 2UH

telephone: +44 (0) 115 823 1115