Diploma degree in Biology, Göttingen, Germany, 1992
PhD, Göttingen, 1995
Research Fellow, School of University of Nottingham, 1996
Senior Research Fellow, University of Nottingham, 2000
Lecturer, Department of Biological Sciences, University of Lancaster, 2006
Associate Professor, School of Life Sciences, University of Nottingham, 2008
Bacterial metabolism and physiology, Clostridia, CO-utilising bacteria, quorum-sensing, metabolic engineering, synthetic biology
Klaus Winzer is a microbiologist with more than 25 years' experience in bacterial physiology and metabolism. He is experienced in bacterial strain isolation, characterisation and engineering, and has… read more
ARENAS-LÓPEZ C, LOCKER J, OROL D, WALTER F, BUSCHE T, KALINOWSKI J, MINTON NP, KOVÁCS K and WINZER K, 2019. The genetic basis of 3-hydroxypropanoate metabolism in Cupriavidus necator H16. Biotechnology for Biofuels. 12, 150 MAGENNIS E.P., FERNANDEZ-TRILLO F., SUI C., SPAIN S.S., CHURCHLEY D., MANTOVANI G, WINZER K. and ALEXANDER C., 2014. Bacteria-instructed synthesis of polymers for self-selective microbial binding and labelling. Nature Materials. 13, 748-755
DARCH, S.E., WEST, S.A., WINZER, K. and DIGGLE, S.P., 2012. Density-dependent fitness benefits in quorum-sensing bacterial populations Proceedings of the National Academy of Sciences of the United States of America. 109(21), 8259-8263
Klaus Winzer is a microbiologist with more than 25 years' experience in bacterial physiology and metabolism. He is experienced in bacterial strain isolation, characterisation and engineering, and has worked extensively in the field of bacterial cell-cell communication. Over his career, Klaus has studied a wide range of physiologically diverse bacteria including numerous pathogens and industrial strains, with an increasing focus on C1-utilising bacteria.
Current efforts focus on understanding and engineering the metabolism of anaerobic clostridia and aerobic gas-fermenting Cupriavidus species, with the ultimate aim of generating platform organisms for the production of biofuels and chemical commodities.
His group is investigating the molecular, genetic, and evolutionary mechanisms that underlay bacterial strain degeneration and study the roles of bacterial signalling in high density fermentations, with the goal of developing more stable and better performing production strains. In collaboration with computational scientists and mathematical modellers the team is working towards integrating complex metabolic pathways into new hosts, using a combination of synthetic biology approaches and in vitro evolution. Current examples include the engineering of carbon monoxide-tolerant and uitilising strains for improved fermentation of industrial wast gases.