Jonathan Hardman

Contact

• workRoom C1716a C-floor, East block.
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 823 1002
• j.hardman@nottingham.ac.uk

Research Summary

Interests

• The development, validation and application of physiological and pathological computational models.
• The development of computational patient-surrogates for research.
• Respiratory physiology & pathology.
• Mechanical ventilation of the lungs & ventilator-associated lung injury.
• Models of cerebrovascular autoregulation.
• Patient safety & complications during anaesthesia.

Techniques

• Development of mathematical models of human physiology & pathology.
• Computer programming and simulation of theoretical models.

Projects

• The determinants of measured alveolar deadspace.
• Modelling analyses of protective ventilation of the lungs.
• Development of a model of cerebrovascular autoregulation.
• Modelling analysis of apnoea and rescue intervention during severe hypoxaemia.
• Carbon dioxide retention in acute exacerbations of chronic obstructive pulmonary disease - modelling VQ and drive alterations.

Centre Collaborators

• Prof. Terence Bennett
• Dr. Ravi Mahajan

Local Collaborators

• Prof Dorotht Auer - functional MRI investigation into the conscious state

UK Collaborators

• Dr Gordon Drummond (Edinburgh)
• Dr John Henderson (Glasgow)
• Dr Roger Fletcher (Cheadle)
• Prof. Oliver Jensen (Nottingham)
• Dr Malachy Columb (Manchester)

International Collaborators

• Dr HU Rothen
• Prof. J Lipman