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Nikos Evangelou

Clinical Associate Professor, Faculty of Medicine & Health Sciences

Personal Details
Research
Publications

Contact

workC floor, South Block
Queen's Medical Centre
Nottingham
NG7 2UH
UK
work0115 8231449
fax0115 849 3300
Nikos.Evangelou@nottingham.ac.uk

Biography

I did my undergraduate studies in Greece and the UK and trained as a Neurologist in Oxford and Nottingham.

I gained my DPhil in Oxford studying axonal damage in MS with MRI and histopathology. Since 2003, I have been appointed Consultant Neurologist at Nottingham University Hospital. In 2011, I joined the University as a Clinical Associate Professor in Neurology.

In 2012 I became clinical lead for the department of Neurology, at the Nottingham University Hospital.

Expertise Summary

I lead a translational group of clinicians and scientists aiming to understand better the pathophysiology of Multiple Sclerosis. I have participated in most major clinical trials in MS. Clinically, I run regular general neurology clinics, but my clinical expertise lies in Multiple Sclerosis and Headache management.

My team is interested in clinical trials in MS and I am the Co-Principle Investigator of a large grant to compare in many sites in the UK and USA escalation vs. highly effective treatment in MS. https://www.pcori.org/research-results/2017/determining-effectiveness-early-intensive-versus-escalation-approaches

Our current MRI research focuses in facilitating the early recognition of demyelinating disorders and quick diagnosis of MS through the demonstration of the pathogenic central vein in demyelinating lesions. We work on 3T and 7T MRI scanners at the medical school and SPMMR centre. We are currently running DECISIVE, an NIHR funded multicentre trial, comparing the central vein with oligoclonal bands.

In addition, we study remyelination in the grey and white matter in vivo using mainly high resolution MTR imaging.

Working with academic neuropsychologists and with the help of the NIHR, we also run a programme grant (NEUROMS) where we try to understand how best to screen for cognitive deficits in MS.

Part of my team is working with NHSEngland and the UK MS Registry, examining how COVID has affected patients with MS.

Teaching Summary

Current supervisor for 7 PhD students

BMedsci homebase join coordinator for Clinical Neuroscience and Psychiatry

Research Summary

Clinical trials

DELIVER MS : https://www.pcori.org/research-results/2017/determining-effectiveness-early-intensive-versus-escalation-approaches

I am also participating in a number of commercial and non-commercial trials as principle investigator in Nottingham.

Neuroimaging

Investigations trying to understand brain disorders (MS and brain injury) and symptoms (cognition impairment, fatigue) through MRI and clinical trials including:

Central veins in MS diagnosis https://clinicaltrials.gov/ct2/show/NCT04024969

The Role of MEG in Assessment and Diagnosis In mTBI (MEGAbIT) https://clinicaltrials.gov/ct2/show/NCT03867513

Neuropsychology of MS

Intervention to support individuals around the point of Multiple Sclerosis diagnosis MS society, a study supported by the MS society. https://clinicaltrials.gov/ct2/show/NCT03735056

Member of the research team of NEUROMS, an NIHR programme grant for the neuropsychological evaluation and rehabilitation in Multiple sclerosis https://neuroms.org/

Selected Publications

TALLANTYRE, E.C., DIXON, J.E., DONALDSON, I., OWENS, T., MORGAN, P.S., MORRIS, P.G. and EVANGELOU, N., 2011. Ultra-high-field imaging distinguishes MS lesions from asymptomatic white matter lesions Neurology. 76(6), 534-539
TALLANTYRE, E.C., BØ, L., AL-RAWASHDEH, O., OWENS, T., POLMAN, C.H., LOWE, J. and EVANGELOU, N., 2009. Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease Brain: a Journal of Neurology. 132(5), 1190-1199
GILMORE, CP, DONALDSON, I, BO, L, OWENS, T, LOWE, J and EVANGELOU, N, 2009. Regional Variations In The Extent And Pattern Of Grey Matter Demyelination In Multiple Sclerosis: A Comparison Between The Cerebral Cortex, Cerebellar Cortex, Deep Grey Matter Nuclei And The Spinal Cord Journal Of Neurology Neurosurgery And Psychiatry. 80(2), 182-187
TALLANTYRE, E.C., BROOKES, M.J., DIXON, J.E., MORGAN, P.S., EVANGELOU, N. and MORRIS, P.G., 2008. Demonstrating the perivascular distribution of MS lesions in vivo with ₇-tesla MRI Neurology. 70(22), 2076-2078

View all publications

Past Research

Neuropathology og Multiple Sclerosis

SINNECKER, TIM, CLARKE, MARGARETA A, MEIER, DOMINIK, ENZINGER, CHRISTIAN, CALABRESE, MASSIMILIANO, DE STEFANO, NICOLA, PITIOT, ALAIN, GIORGIO, ANTONIO, SCHOONHEIM, MENNO M, PAUL, FRIEDEMANN, PAWLAK, MIKOLAJ A, SCHMIDT, REINHOLD, KAPPOS, LUDWIG, MONTALBAN, XAVIER, ROVIRA, ALEX, EVANGELOU, NIKOS and WUERFEL, JENS, 2019. Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis. JAMA neurology.
ONTANEDA, DANIEL, TALLANTYRE, EMMA, KALINCIK, TOMAS, PLANCHON, SARAH M and EVANGELOU, NIKOS, 2019. Early highly effective versus escalation treatment approaches in relapsing multiple sclerosis. The Lancet. Neurology.
SINNECKER, TIM, CLARKE, MARGARETA, MEIER, DOMINIK, ENZINGER, CHRISTIAN, CALABRESE, MASSIMILIANO, DE STEFANO, NICOLA, PITIOT, ALAIN, GIORGIO, ANTONIO, SCHOONHEIM, MENNO M., PAUL, FRIEDEMANN, PAWLAK, MIKOLAJ, KAPPOS, LUDWIG, ROVIRA, ALEX, EVANGELOU, NIKOLAOS and WURFEL, JENS, 2019. Evaluation of the "Three Lesions with a Central Vein Sign" Criteria for the Differentiation between Multiple Sclerosis and its Imaging Mimics NEUROLOGY. 92(15),
CADAVID, DIEGO, MELLION, MICHELLE, HUPPERTS, RAYMOND, EDWARDS, KEITH R., CALABRESI, PETER A., DRULOVIC, PLENA, GIOVANNONI, GAVIN, HARTUNG, HANS-PETER, ARNOLD, DOUGLAS L., FISHER, ELIZABETH, RUDICK, RICHARD, MI, SHA, CHOI, YI, LI, JIE, ZHANG, YIWEI, CHENG, WENTING, XU, LEI, ZHU, BING, GREEN, SUSAN M., CHANG, IH, DEYKIN, AARON and SHEIKH, SARAH, I, 2019. Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial LANCET NEUROLOGY. 18(9), 845-856
2018. Ultra-high-field arterial spin labelling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis European Radiology. (In Press.)
PAPATHANASIOU A, ABDEL-FAHIM R and EVANGELOU N, 2018. Dual infectious brainstem encephalitis with Aspergillus flavus and Haemophilus influenza in an immunocompetent patient. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 39(10), 1795-1796
GERALDES R, CICCARELLI O, BARKHOF F, DE STEFANO N, ENZINGER C, FILIPPI M, HOFER M, PAUL F, PREZIOSA P, ROVIRA A, DELUCA GC, KAPPOS L, YOUSRY T, FAZEKAS F, FREDERIKSEN J, GASPERINI C, SASTRE-GARRIGA J, EVANGELOU N and , 2018. The current role of MRI in differentiating multiple sclerosis from its imaging mimics. Nature reviews. Neurology. 14(4), 213
SAMARAWEERA A, CLARKE M and EVANGELOU N, 2017. The Central Vein Sign in Multiple Sclerosis Lesions Is Present Irrespective of the T2* Sequence at 3 T. Journal of neuroimaging. 27(1), 114-121
BARRATT EL, TEWARIE PK, CLARKE MA, HALL EL, GOWLAND PA, MORRIS PG, FRANCIS ST, EVANGELOU N and BROOKES MJ, 2017. Abnormal task driven neural oscillations in multiple sclerosis: A visuomotor MEG study. Human brain mapping. 38(5), 2441-2453
MCKEE JB, COTTRIALL CL, ELSTON J, EPPS S, EVANGELOU N, GERRY S, KENNARD C, KONG Y, KOELEWYN A, KUEKER W, LEITE MI, PALACE J and CRANER M, 2017. Amiloride does not protect retinal nerve fibre layer thickness in optic neuritis in a phase 2 randomised controlled trial. Multiple sclerosis (Houndmills, Basingstoke, England). 1352458517742979 (In Press.)
CRONIN MJ, WHARTON S, AL-RADAIDEH A, CONSTANTINESCU C, EVANGELOU N, BOWTELL R and GOWLAND PA, 2016. A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field. Magma (New York, N.Y.). 29(3), 543-57
MISTRY, NIRAJ, ABDEL-FAHIM, RASHA, SAMARAWEERA, AMAL, MOUGIN, OLIVIER, TALLANTYRE, EMMA, TENCH, CHRISTOPHER, JASPAN, TIM, MORRIS, PETER, MORGAN, PAUL S. and EVANGELOU, NIKOS, 2016. Imaging central veins in brain lesions with 3-T T2*-weighted magnetic resonance imaging differentiates multiple sclerosis from microangiopathic brain lesions MULTIPLE SCLEROSIS JOURNAL. 22(10), 1289-1296
FILIPPI, MASSIMO, ROCCA, MARIA A., CICCARELLI, OLGA, DE STEFANO, NICOLA, EVANGELOU, NIKOS, KAPPOS, LUDWIG, ROVIRA, ALEX, SASTRE-GARRIGA, JAUME, TINTORE, MAR, FREDERIKSEN, JETTE L., GASPERINI, CLAUDIO, PALACE, JACQUELINE, REICH, DANIEL S., BANWELL, BRENDA, MONTALBAN, XAVIER and BARKHOF, FREDERIK, 2016. MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines LANCET NEUROLOGY. 15(3), 292-303
CRONIN, MATTHEW JOHN, WHARTON, SAMUEL, AL-RADAIDEH, ALI, CONSTANTINESCU, CRIS, EVANGELOU, NIKOS, BOWTELL, RICHARD and GOWLAND, PENNY ANNE, 2016. A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 29(3), 543-557
SATI P, OH J, CONSTABLE RT, EVANGELOU N, GUTTMANN CR, HENRY RG, KLAWITER EC, MAINERO C, MASSACESI L, MCFARLAND H, NELSON F, ONTANEDA D, RAUSCHER A, ROONEY WD, SAMARAWEERA AP, SHINOHARA RT, SOBEL RA, SOLOMON AJ, TREABA CA, WUERFEL J, ZIVADINOV R, SICOTTE NL, PELLETIER D, REICH DS and , 2016. The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative. Nature reviews. Neurology. (In Press.)
RODRÍGUEZ CRUZ PM, MATTHEWS L, BOGGILD M, CAVEY A, CONSTANTINESCU CS, EVANGELOU N, GIOVANNONI G, GRAY O, HAWKINS S, NICHOLAS R, OPPENHEIMER M, ROBERTSON N, ZAJICEK J, ROTHWELL PM and PALACE J, 2016. Time- and Region-Specific Season of Birth Effects in Multiple Sclerosis in the United Kingdom. JAMA neurology. 73(8), 954-60
RICE CM, MARKS DI, BEN-SHLOMO Y, EVANGELOU N, MORGAN PS, METCALFE C, WALSH P, KANE NM, GUTTRIDGE MG, MIFLIN G, BLACKMORE S, SARKAR P, REDONDO J, OWEN D, COTTRELL DA, WILKINS A and SCOLDING NJ, 2015. Assessment of bone marrow-derived Cellular Therapy in progressive Multiple Sclerosis (ACTiMuS): study protocol for a randomised controlled trial. Trials. 16, 463
MOUGIN O., ABDEL-FAHIM R., DINEEN R., PITIOT A., EVANGELOU N. and GOWLAND P., 2015. Imaging gray matter with concomitant null point imaging from the phase sensitive inversion recovery sequence. Magnetic resonance in medicine. (In Press.)
SAMARAWEERA AP, COHEN SN, AKAY EM and EVANGELOU N, 2015. Lymphomatoid papulosis: A cutaneous lymphoproliferative disorder in a patient on fingolimod for multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). 22(1), 122-4
SORMANI MP and EVANGELOU N, 2015. New imaging language skills required in MS. Neurology. 85(13), 1096-7
JURYŃCZYK M, WEINSHENKER B, AKMAN-DEMIR G, ASGARI N, BARNES D, BOGGILD M, CHAUDHURI A, D'HOOGHE M, EVANGELOU N, GERALDES R, ILLES Z, JACOB A, KIM HJ, KLEITER I, LEVY M, MARIGNIER R, MCGUIGAN C, MURRAY K, NAKASHIMA I, PANDIT L, PAUL F, PITTOCK S, SELMAJ K, DE SÈZE J, SIVA A, TANASESCU R, VUKUSIC S, WINGERCHUK D, WREN D, LEITE I and PALACE J, 2015. Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes. Journal of neurology. 263(1), 140-9
MCKEE JB, ELSTON J, EVANGELOU N, GERRY S, FUGGER L, KENNARD C, KONG Y, PALACE J and CRANER M, 2015. Amiloride Clinical Trial In Optic Neuritis (ACTION) protocol: a randomised, double blind, placebo controlled trial. BMJ open. 5(11), e009200
MISTRY N, ABDEL-FAHIM R, SAMARAWEERA A, MOUGIN O, TALLANTYRE E, TENCH C, JASPAN T, MORRIS P, MORGAN PS and EVANGELOU N, 2015. Imaging central veins in brain lesions with 3-T T2*-weighted magnetic resonance imaging differentiates multiple sclerosis from microangiopathic brain lesions. Multiple sclerosis (Houndmills, Basingstoke, England). 22(10), 1289-96
SORMANI, MARIA PIA and EVANGELOU, NIKOS, 2015. New imaging language skills required in MS NEUROLOGY. 85(13), 1096-1097
KITLEY J, EVANGELOU N, KÜKER W, JACOB A, LEITE MI and PALACE J, 2014. Catastrophic brain relapse in seronegative NMO after a single dose of natalizumab. Journal of the neurological sciences. 339(1-2), 223-5
STROMAN, P. W., WHEELER-KINGSHOTT, C., BACON, M., SCHWAB, J. M., BOSMA, R., BROOKS, J., CADOTTE, D., CARLSTEDT, T., CICCARELLI, O., COHEN-ADAD, J., CURT, A., EVANGELOU, N., FEHLINGS, M. G., FILIPPI, M., KELLEY, B. J., KOLLIAS, S., MACKAY, A., PORRO, C. A., SMITH, S., STRITTMATTER, S. M., SUMMERS, P. and TRACEY, I., 2014. The current state-of-the-art of spinal cord imaging: Methods NEUROIMAGE. 84, 1070-1081
WHEELER-KINGSHOTT, C. A., STROMAN, P. W., SCHWAB, J. M., BACON, M., BOSMA, R., BROOKS, J., CADOTTE, D. W., CARLSTEDT, T., CICCARELLI, O., COHEN-ADAD, J., CURT, A., EVANGELOU, N., FEHLINGS, M. G., FILIPPI, M., KELLEY, B. J., KOLLIAS, S., MACKAY, A., PORRO, C. A., SMITH, S., STRITTMATTER, S. M., SUMMERS, P., THOMPSON, A. J. and TRACEY, I., 2014. The current state-of-the-art of spinal cord imaging: Applications NEUROIMAGE. 84, 1082-1093
OWENS T, EVANGELOU N and WHYNES DK, 2013. Rationing and deprivation: disease-modifying therapies for multiple sclerosis in the United Kingdom. The European journal of health economics : HEPAC : health economics in prevention and care. 14(2), 315-21
TANASESCU R, EVANGELOU N and CONSTANTINESCU CS, 2013. Role of oral teriflunomide in the management of multiple sclerosis. Neuropsychiatric disease and treatment. 9, 539-53
MISTRY, N., DIXON, J., TALLANTYRE, E., TENCH, C., ABDEL-FAHIM, R., JASPAN, T., MORGAN, P.S., MORRIS, P. and EVANGELOU, N., 2013. Central veins in brain lesions visualized with high-field magnetic resonance imaging: a pathologically specific diagnostic biomarker for inflammatory demyelination in the brain JAMA Neurology. 70(5), 623-628
MATTHEWS, L, MARASCO,R, JENKINSON,M, KUKER,W, LUPPE,S, LEITTE,M, GIORGIO,A, DE STEFANO,N, ROBERTSON,N, JOHANSEN-BERG,H, EVANGELOU,N and PALACE,J, 2013. Distinction of seropositive NMO spectrum disorder and MS brain lesion distribution. Neurology. 80(14), 1330-7
STROMAN PW, WHEELER-KINGSHOTT C, BACON M, SCHWAB JM, BOSMA R, BROOKS J, CADOTTE D, CARLSTEDT T, CICCARELLI O, COHEN-ADAD J, CURT A, EVANGELOU N, FEHLINGS MG, FILIPPI M, KELLEY BJ, KOLLIAS S, MACKAY A, PORRO CA, SMITH S, STRITTMATTER SM, SUMMERS P and TRACEY I, 2013. The current state-of-the-art of spinal cord imaging: methods. NeuroImage. 84, 1070-81
MOUGIN, O. E., ABDEL-FAHIM, R., HALL, E., PITIOT, A., GOWLAND, P. and EVANGELOU, N., 2013. Cortical lesion classification in multiple sclerosis using 3D interleaved phase sensitive inversion recovery imaging and an inherent null point image MULTIPLE SCLEROSIS JOURNAL. 19(11), 422-422
TAYLOR TR, EVANGELOU N, PORTER H and LENTHALL R, 2012. Primary Care Direct Access Mri For The Investigation Of Chronic Headache. Clinical Radiology. 67(1), 24-7
FILLIPI,M, ROCCA,M, BARKHOF F, BRÜCK W, CHEN JT, COMI G, DELUCA G, DE STEFANO N, ERICKSON BJ, EVANGELOU N, FAZEKAS F, GEURTS JJ, LUCCHINETTI C, MILLER DH, PELLETIER D, POPESCU BF and LASSMANN H, 2012. Association between pathological and MRI findings in multiple sclerosis Lancet Neurol.. 11(4), 349-360
EVANGELOU,N, 2012. The only way to manage neurodegeneration in MS is to prevent it with effective anti-inflammatory therapy: Yes Mult Scler. 18(12), 1680-81
MISTRY N, TALLANTYRE EC, DIXON JE, GALAZIS N, JASPAN T, MORGAN PS, MORRIS P and EVANGELOU N, 2011. Focal Multiple Sclerosis Lesions Abound In 'Normal Appearing White Matter'. Multiple Sclerosis (Houndmills, Basingstoke, England). 17(11), 1313-23
TALLANTYRE, E.C., DIXON, J.E., DONALDSON, I., OWENS, T., MORGAN, P.S., MORRIS, P.G. and EVANGELOU, N., 2011. Ultra-high-field imaging distinguishes MS lesions from asymptomatic white matter lesions Neurology. 76(6), 534-539
DIXON JE, SIMPSON A, MISTRY N, EVANGELOU N and MORRIS PG, 2011. Optimisation Of T(2)(*)-Weighted Mri For The Detection Of Small Veins In Multiple Sclerosis At 3T And 7T. European Journal Of Radiology. 82(5), 719-27
TALLANTYRE, EC, MORGAN, PS, DIXON, JE, AL-RADAIDEH, A, BROOKES, MJ, MORRIS, PG and EVANGELOU, N, 2010. 3 Tesla And 7 Tesla Mri Of Multiple Sclerosis Cortical Lesions Journal Of Magnetic Resonance Imaging. 32(4), 971-977
TALLANTYRE, EC, BO, L, AL-RAWASHDEH, O, OWENS, T, POLMAN, CH, LOWE, JS and EVANGELOU, N, 2010. Clinico-Pathological Evidence That Axonal Loss Underlies Disability In Progressive Multiple Sclerosis Multiple Sclerosis. 16(4), 406-411
TALLANTYRE, E.C., BØ, L., AL-RAWASHDEH, O., OWENS, T., POLMAN, C.H., LOWE, J. and EVANGELOU, N., 2009. Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease Brain: a Journal of Neurology. 132(5), 1190-1199
GILMORE, C.P., DELUCA, G.C., BO, L., OWENS, T., LOWE, J., ESIRI, M.M. and EVANGELOU, N., 2009. Spinal cord neuronal pathology in multiple sclerosis Brain Pathology. 19(4), 642-649
BAIRD, W, JACKSON, R, FORD, H, EVANGELOU, N, BUSBY, M, BULL, P and ZAJICEK, J, 2009. Holding Personal Information In A Disease-Specific Register: The Perspectives Of People With Multiple Sclerosis And Professionals On Consent And Access Journal Of Medical Ethics. 35(2), 92-96
GILMORE, CP, DONALDSON, I, BO, L, OWENS, T, LOWE, J and EVANGELOU, N, 2009. Regional Variations In The Extent And Pattern Of Grey Matter Demyelination In Multiple Sclerosis: A Comparison Between The Cerebral Cortex, Cerebellar Cortex, Deep Grey Matter Nuclei And The Spinal Cord Journal Of Neurology Neurosurgery And Psychiatry. 80(2), 182-187
GILMORE, CP, JACOB, A and EVANGELOU, N, 2009. A Case Of Neuromyelitis Optica With Gadolinium-Enhancing Brain Lesions And Parinaud Syndrome
GILMORE, CP, GEURTS, JJG, EVANGELOU, N, BOT, JCJ, VAN SCHIJNDEL, RA, POUWELS, PJW, BARKHOF, F and BO, L, 2009. Spinal Cord Grey Matter Lesions In Multiple Sclerosis Detected By Post-Mortem High Field Mr Imaging Multiple Sclerosis. 15(2), 180-188
TALLANTYRE, E.C., BROOKES, M.J., DIXON, J.E., MORGAN, P.S., EVANGELOU, N. and MORRIS, P.G., 2008. Demonstrating the perivascular distribution of MS lesions in vivo with ₇-tesla MRI Neurology. 70(22), 2076-2078
GILMORE, CP, BO, L, OWENS, T, LOWE, J, ESIRI, MM and EVANGELOU, N, 2006. Spinal Cord Gray Matter Demyelination In Multiple Sclerosis - A Novel Pattern Of Residual Plaque Morphology Brain Pathology. 16(3), 202-208
DELUCA, GC, WILLIAMS, K, EVANGELOU, N, EBERS, GC and ESIRI, MM, 2006. The Contribution Of Demyelination To Axonal Loss In Multiple Sclerosis Brain. 129, 1507-1516
BURWICK, RM, RAMSAY, PP, HAINES, JL, HAUSER, SL, OKSENBERG, JR, PERICAK-VANCE, MA, SCHMIDT, S, COMPSTON, A, SAWCER, S, CITTADELLA, R, SAVETTIERI, G, QUATTRONE, A, POLMAN, CH, UITDEHAAG, BMJ, ZWEMMER, JNP, HAWKINS, P, OLLIER, WER, WEATHERBY, S, ENZINGER, C, FAZEKAS, F, SCHMIDT, H, SCHMIDT, R, HILLERT, J, MASTERMAN, T, HOGH, P, NIINO, M, KIKUCHI, S, MACIEL, P, SANTOS, M, RIO, ME, KWIECINSKI, H, ZAKRZEWSKA-PNIEWSKA, B, EVANGELOU, N, PALACE, J and BARCELLOS, LF, 2006. Apoe Epsilon Variation In Multiple Sclerosis Susceptibility And Disease Severity - Some Answers
NIEPEL, G, TENCH, CR, MORGAN, PS, EVANGELOU, N, AUER, DP and CONSTANTINESCU, CS, 2006. Deep Gray Matter And Fatigue In Ms - A T1 Relaxation Time Study Journal Of Neurology. 253(7), 896-902
EVANGELOU, N, DELUCA, GC, OWENS, T and ESIRI, MM, 2005. Pathological Study Of Spinal Cord Atrophy In Multiple Sclerosis Suggests Limited Role Of Local Lesions Brain. 128, 29-34
GILMORE, CP, DELUCA, GC, BO, L, OWENS, T, LOWE, J, ESIRI, MM and EVANGELOU, N, 2005. Spinal Cord Atrophy In Multiple Sclerosis Caused By White Matter Volume Loss Archives Of Neurology. 62(12), 1859-1862
LIN, X, TENCH, CR, EVANGELOU, N, JASPAN, T and CONSTANTINESCU, CS, 2004. Measurement Of Spinal Cord Atrophy In Multiple Sclerosis Journal Of Neuroimaging. 14(3), 20S-26S
EVANGELOU, N, LITTLEWOOD, T, ANSLOW, P and CHAPEL, H, 2003. Transverse Sinus Thrombosis And Ivig Treatment: A Case Report And Discussion Of Risk-Benefit Assessment For Immunoglobulin Treatment Journal Of Clinical Pathology. 56(4), 308-309
PRICE, CJS, EVANGELOU, N and GREGORY, R, 2002. Amyloid Neuropathy Presenting As Thoraco-Abdominal Parathesia
EVANGELOU, N, KONZ, D, ESIRI, MM, SMITH, S, PALACE, J and MATTHEWS, PM, 2001. Size-Selective Neuronal Changes In The Anterior Optic Pathways Suggest A Differential Susceptibility To Injury In Multiple Sclerosis Brain. 124, 1813-1820
EVANGELOU, N, KONZ, D, ESIRI, MM, SMITH, S, PALACE, J and MATTHEWS, PM, 2000. Regional Axonal Loss In The Corpus Callosum Correlates With Cerebral White Matter Lesion Volume And Distribution In Multiple Sclerosis Brain. 123, 1845-1849
EVANGELOU, N, ESIRI, MM, SMITH, S, PALACE, J and MATTHEWS, PM, 2000. Quantitative Pathological Evidence For Axonal Loss In Normal Appearing White Matter In Multiple Sclerosis Annals Of Neurology. 47(3), 391-395
EVANGELOU, N, JACKSON, M, BEESON, D and PALACE, J, 1999. Association Of The Apoe Epsilon 4 Allele With Disease Activity In Multiple Sclerosis Journal Of Neurology Neurosurgery And Psychiatry. 67(2), 203-205