Precision Healthcare and Safety of Medicines (PRISM) research group
In the PRISM research group we aim to generate the evidence base for effective, safe, equitable, and patient-focused care. Our research focuses on approaches in primary care – where over 90% of health care is delivered. We are at the forefront of research in the UK on big data analysis, patient safety and translating genomics into practice.
We use a combination of pragmatic health service research and large scale analysis of electronic health records. This enables us to:
- better understand the epidemiology of diseases
- develop appropriate risk prediction tools
- undertake implementation research, with a particular focus on tackling inequalities
Research themes
Precision medicine
Precision medicine: using advances in data science and genomic medicine to ensure the right care is given to the right person at the right time.
Risk prediction
Risk prediction: we have led in the development of risk prediction algorithms for health issues such as cardio-metabolic disease, fractures and cancer.
Inequalities
Inequalities: historically underserved communities have not benefited from advancements in healthcare. A core principle of our group is to ensure all of our work considers opportunities to reduce inequalities.
Safety and effectiveness of medicines
Safety and effectiveness of medicines: we have been internationally recognised in developing and implementing primary care tools to reduce medication errors and associated serious harms.
Multimorbidity
Multimorbidity: we have recognised that with our ageing population diseases do not present in isolation but co-exist and interact. This is exemplified by our work using big data analysis, incorporating machine learning techniques.
People
View the PRISM team.
Patient and public involvement
Patient and public involvement (PPI) runs through all of our research activities. Experts by experience help devise research questions, advise on study designs, interpret findings and co-author publications. We have a particular interest in engaging individuals from underserved communities. Below is a video where public contributors discuss their time working on one of our projects.