Module convenor for Research Projects. I also teach anatomy/histology/cardiorespiratory in a number of Veterinary Medicine and Science modules. I previously convened Cardiorespiratory 1.
Module convenor for three Nottingham Advantage Award modules.
Committee member and Representative of the European Association of Veterinary Anatomists.
Member of the International Committee on Veterinary Gross Anatomical Nomenclature (I.C.V.G.A.N.) working on Nomina Anatomica Veterinaria.
Member of the Nottingham Recognition Scheme committee, mentoring and assessing Higher Education Academy recognition applications.
External examiner for another UK Vet School.
My research areas are integrated the School of Veterinary Medicine and Research themes and concentrates on cardiovascular disorders (heart disease and angiogenesis) and anatomy.
Developmental Cardiovascular Medicine: My investigations centre around the developing cardiovascular system and include researching cardiac disorders and angiogenesis. One area of interest uses knock down models and information from humans to discover possible disease causing genes. In addition to investigating humans and models, my group concentrate on looking into companion animals that are suffering from cardiovascular disorders and trying to elucidate the genes that are affected/causative. A number of techniques are used including molecular, cellular, histological, imaging, protein and more recently the epigenetics of disorders are being investigated.
Developmental Reproduction and Metabolism: My research focuses on the normal development of the fetus and placenta and includes projects investigating the genetic, proteomic, epigenetic, anatomical, histological and functional effects of a low protein diet during development, and normal metabolism mechanisms throughout development in a number of species and have an underlying theme of angiogenesis and metabolism. The angiogenesis work also includes blood vessel casting, CT scanning and micobial interactions - especially within our lameness, laminitis and footrot projects. The angiogenesis work within my group also covers research into ocular diseases, especially those presenting with abnormal vasculature. The laboratory combines the angiogenesis theme with ocular metabolism studies within both the normal eye and disease affected eyes.
My research investigates both naturally-acquired and induced diseases in many species throughout development, into adulthood and in old age. The overall aim of the work is to elucidate the molecular mechanisms behind both normal and diseased states.
Overall Aims of the Research: The work that we are undertaking will help us to better understand disorders including cardiomyopathies and blindness, and nutrition requirements, so more effective diagnosis techniques, treatments and advice for patients can be developed. An integrated approach to disease and development is undertaken and therefore collaborators include scientists and clinicians and a number of veterinary surgeons.
Student achievement and support:
I investigate the effects of educational and socioeconomic background, gender and nationality upon the student experience and grade achievements, using both qualitative and quantitative approaches. I have also researched student support requirements in relation to tutorial systems.
My veterinary education research revolves around developing the SVMS online veterinary museum to enable more effective learning and also includes developing teaching and museum materials. I also collaborated on the international online anatomy museum grant (OVAM) and continue to support and develop the initiative and I am a WikiVet Trustee.
Present funding: BBSRC. MRC. BHF. Academy of Medical Sciences+Wellcome Trust. AHDB. Vice-Chancellor's Scholarship for Research Excellence. Petplan. Waltham Foods. Nottingham Strategic Award. Industrial awards. INSpire Award.
Past funding includes: BBSRC, BHF, JISC, EBLEX, Higher Education Academy, Royal Society, Anatomical Society of Great Britain and Ireland, British Society for Developmental Biology, Talent Builder internships, Cascade Impact, Weston Scholarship, CEVA.
SIMPSON S, DUNNING MD, BROWNLIE S, PATEL J, GODDEN M, COBB M, MONGAN NP and RUTLAND CS, 2017. Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy. BioMed research international. 2016, 6374082 KOVAC, M., LITVIN, YA., ALIEV, RO., ZAKIROVA, EU., RUTLAND, CS., KIYASOV, AP. and RIZVANOV, AA., 2017. Gene Therapy Using Plasmid DNA Encoding Vascular Endothelial Growth Factor 164 and Fibroblast Growth Factor 2 Genes for the Treatment of Horse Tendinitis and Desmitis: Case Reports Front. Vet. Sci.. 4, ENGLAND J, GRANADOS-RIVERON J, POLO-PARADA L, KURIAKOSE D, MOORE C, BROOK JD, RUTLAND CS, SETCHFIELD K, GELL C, GHOSH TK, BU'LOCK F, THORNBOROUGH C, EHLER E and LOUGHNA S, 2017. Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects. Journal of molecular and cellular cardiology. 106, 1-13
SIOBHAN SIMPSON, PAUL RUTLAND and CATRIN SIAN RUTLAND, 2017. Genomic Insights into Cardiomyopathies: A Comparative Cross-Species Review Vet. Sci.. 4(1),
Present Laboratory Members:
Aziza Alibhai - Senior researcher
Ramzi Al-Agele - PhD (with Dr Rauch)
Michael Agbaje - PhD (with Dr Totemeyer and Dr Jones)
Lola Ruiz Diaz - PhD Vice-Chancellor's Scholarship for Research Excellence (with Associate Profs Mongan and Perry), previously research assistant.
Emma Lund - PhD BBSRC (with Associate Prof Mongan)
Veronika Metzler - PhD BBSRC (Associate Prof Mongan and Prof Heery)
Daisy Haigh - PhD BBSRC (with Associate Prof Mongan and Prof Fray)
James Wilson - PhD AHDB (with Profs Huxley and Green)
Sophie Taylor - MRes (Associate Prof Rauch)
Emily Paul and Corinne Woodcock - BBSRC DTP rotation students (with Associate Professors Mongan and Dunning)
Dr Siobhan Simpson - BBSRC PhD (with Dr Mongan and Prof Cobb)
Dr Jennifer Edwards - BBSRC PhD (with Dr Mongan, Dr Robinson and Dr Perry)
Dr Matthew Parnall - BHF PhD (with Dr Loughna)
Emily Paul - Weston Award Scholarship MRes (with Dr Rauch)
Verdana Rani - MRes (with Dr Mongan)
Kavish Amin - MRes (with Dr Mongan and Dr Fray)
Joseph Wightman - Life Sciences MSc (with Prof Mongan)
Richard Ryder - MSc (with Dr Totemeyer)
Dr Paula Wong nee Baskeyfield - Clinical internship (with Dr Mongan and Prof Cobb)
Luana Garcia dos Santos - Science without Borders internship (with Dr Mongan)
Holly Graham - Clinical research internship
Gar Wai Kerry Chung - Graduate Intern and research technician
Paul (Pablo) Barrett - Graduate Intern
Mariam Saigar - Researcher and scientific writer
Claire Bordoli - Cascade E-Museum curator and research technician
Kirsty Hillier - Cascade E-Museum curator
Adeel Khan - JISC museum E-curator
Madeline Mestas, Georgia Miller, Keshia Merry - INSpire studentships 2017
Matthew Keane - BBSRC 2015 studentship (with Dr Mostyn and Prof. Huxley)
Jenny Price and Agata Witkowska- 2013 BBSRC studentship and 2014/15 clinical research intern
Zoe Hood + Zoe Stokes - 2014 BBSRC Summer studentship, 2015 research intern
Chloe Hughes - 2012 BBSRC Summer studentship, JISC OVAM museum curator and clinical placement student.
Ammar Alibhai - 2011 BBSRC Summer studentship, Cascade funded educational web page designer
Emilia Harding - 2010 BBSRC Summer studentship, anatomy research/web design
Dulcie Smith and Katie White - Clinical EMS
Mark Plested, Sarah Geldart, Robin Cheung, Chloe Hughes, Agata WItkowska, Meghan Moore, Stephanie Barnett, Carolize Compton, Lauren Porteous, Thomas Mignan, Madeleine Nyberg, Hannah Partridge, Holly Graham, Janika Patel, Henry Johnson, Megan Godden, Nuria Holzleg, Elise Moritz, Matthew Keane, Rachel Woolley, Kyle Eadie, Imogen Purvis, Katie White, Dulcie Smith, Keshia Merry, Georgia Miller - Research projects
Melissa Bexon, Rhys Owen, Riaz Rhemu, Lottie Back - Assisted supervision of research projects