1.1.5 Late-onset single-gene disorders

An individual might know that a late-onset disease such as Huntington's disease (HD) is present in their immediate family and that they might have inherited the disease gene(s). The problems of genetic testing for HD revolve around the fact that it is pre-symptomatic.

One dilemma is the long delay between testing positive and developing the clinical symptoms of the disorder in middle age. Is it better not to know and live in hope, or as one victim cried ‘get it over, I'm so tir
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Acknowledgements

Except for third party materials and otherwise stated (see terms and conditions), this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence

Grateful acknowledgement is made to the following sources for permission to reproduce materia
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01B - Introduction à la culture numérique (CN16-17) (suite) (audio)

Cours commun de culture numérique 2016-2017 - Hervé Le Crosnier

Cours commun M1-DNR2i, Licence Professionnelle ATP, M1-EMT, M1-ESPE, M2-MDS, M2-Green

Cours 1
16 septembre
- Introduction : qu’entend-on par culture numérique

Cours 2
23 septembre
- Histoire technique et sociale de l'informatique et de l'internet

Cours 3
30 septembre - Le ...
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2.1.1 The morality play

Before looking at the play's opening scene I should add a brief note on the medieval morality play, the type of drama on which Marlowe draws in adapting The Damnable Life for the stage. After the Prologue and Faustus's long opening speech, you may have been startled by the appearance of the Good and Evil Angels. Even if you had expected to find supernatural beings in a play about a man who sells his soul to the devil, the Good and Evil Angels may have struck you as strange, perh
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3.5 Summary

Phenomenologists focus on how bodies are experienced at a subjective and intersubjective (relational) level. Phenomenological psychologists seek to transcend the mind-body dualism, arguing that all we have is an intelligent body, with the body and mind one and the same: not simply biology; we are our body and, through this, perform selfhood. This bodily experience is also often pre-reflective and extra-discursive – we experience and use our body before we think about it. And it is through u
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355 GG Subject Object
Why "I love you" is the easiest way ever to remember the difference between subject and object.
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Hepatocellular Carcinoma in Olmsted County, Minnesota, 1976-2008.
By: WentzMR Dr. W. Ray Kim, Associate Professor of Medicine and Hepatologist at Mayo Clinic in Rochester, MN, discusses his article appearing in the January 2012 issue of Mayo Clinic Proceedings, reporting on a 2-fold increase in the incidence of liver cancer during the past 3 decades, primarily in conjunction with the rate of hepatitis C infection. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(11)00004-8/fulltext
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Rupinder Brar on Relativity, Einstein, and How to Stay Young
Rupinder Brar lectures on the topic of Einstein's special relativity theory and it's explanation of time dilation and simultaneity. The lecture is entitled Relativity, Einstein, the Speed of Light and How to Stay Young.
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Valley Forge, 1777 (The American Revolution)
When the Continental Army made camp at Valley Forge during the American Revolution, times were tough. The winter was bitter cold, and there was disease and hunger. (01:30)

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4 From DNA to RNA: transcription

In the process of transcription, the information in a gene, i.e. the DNA base sequence, is copied, or transcribed, to form an RNA molecule. RNA is therefore an intermediary in the flow of information from DNA to protein. Before we consider the details of transcription, we will first look at the structure of RNA.

The name ribonucleic acid suggests that RNA is chemically related to DNA. Like DNA, RNA is a chain of nucleotides.

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Learning outcomes

After studying this course, you should be able to:

  • understand some of the ways in which genetic knowledge could affect medical practice, in particular in relation to predictive medicine

  • understand how populations are screened for conditions such as phenylketonuria and whether screening could be used for carriers of recessive genetic disorders such as cystic fibrosis

  • understand how gene chips may be used to screen for large numbers of genes at once,
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#253: Sedimental journey: Probing climate's buried past to predict our future

Paleoclimatologist Prof Jonathan Overpeck describes how research into uncovering the earth’s climate history generates important insights about our climate future. Presented by Dr Shane Huntington.