Medicines by Design
Medicines By Design aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. Much of the most promising pharmacological research going on at universities across the country is sponsored by the National Institute of General Medical
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Essential Science for Teachers: Physical Science: Session 2. The Particle Nature of Matter: Solids,
In-depth interviews with children that uncover their ideas about the topic at hand.,The segment provides examples of questions used to probe the student's ideas about particles, particularly, that substances such as air are made up of invisible tiny particles called atoms that are far too small to be seen through a regular microscope. When asked if he could draw air, the student responds that air cannot be drawn because it is just a bunch of invisible particles called atoms, but when probed furt
Author(s): Harvard-Smithsonian Center for Astrophysics

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The Chemistry of Health
This site tells how chemistry and biochemistry are increasing our understanding of human health. Learn how biochemical relays keep our organ systems operating, how food is broken down and used to build tissues and organs, and how tiny biological probes and instruments can track single molecules. Topics in the 60-page booklet include folic acid, sugars and fats, DNA, making medicines, harnessing biology's magic, and more.
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Rare organ transplant gives single mom new lease on life
A single mom from North Carolina recently received an extremely rare triple transplant. She received a new heart, lungs and a liver and is enjoying her new lease on life. Shereyse Joyner from Ahoskie, NC, is believed to be only the twelfth patient in the U.S. since 1988 to receive the triple organ transplant. She was diagnosed with pulmonary hypertension and impending organ failure in 2006, and her health steadily declined. "It started off with the lungs, where I was short of breath and I cou
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The News: HeartMate II
In this commercial, we open on a doctor reading a thank-you letter from a patient. Dr. Jennifer Peura tells us how in medical school, she dreamed of finding all the answers for her patients. She explains how heart patients for years were tethered to a giant device, until MUSC acquired a device the size of a cell phone to replace their failing hearts. She is summoned to a patient room, where we see that her heart patient is now a proud uncle, celebrating the birth of his niece.
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Model of the monoclinic ZrO2 unit cell
Rotating model of the monoclinic ZrO2 unit cell.
Author(s): DoITPoMS, University of Cambridge

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The "Predator" Infiltrates French Ad Building At WSU!
10/29/2010 The Predator Infiltrates French Ad Building At Washington State University! Media Contact: Matt Haugen, WSU News Service, 509-335-0487, mhaugen@wsu.edu PULLMAN, Wash.— No one was safe during the noon hour Friday at WSU, as "the Predator"—from the Hollywood movies of the same name— descended on the French Administration Building. Terror and fear was struck into the souls of the defenseless humans who tried to fight their way from the brick and mortar building. Or maybe peop
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Lesson 02 - One Minute Luxembourgish
In lesson 02 of One Minute Luxembourgish you will learn a few more useful words in Luxembourgish which you'll use every day. Remember - even a few phrases of a language can help you make friends and enjoy travel more. Find out more about One Minute Languages at our website - http://www.oneminutelanguages.com. One Minute Luxembourgish is brought to you by the Radio Lingua Network and is ©Copyright 2008.
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Acknowledgements

Grateful acknowledgement is made to the following sources for permission to reproduce material in this course:

Couse image: Mike in Flickr made available under Creative Commons Attribution-NonCommercial-ShareAlike 2.0 Licence.

The content acknowledg
Author(s): The Open University

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Stem cells: the future of medicine?
Dr Adam Giangreco views stem cell research as the best promise for medical breakthroughs over the next few decades. Dr Giangreco, a recent recipient of a major European Research Council grant, explains how he is exploring new treatments for lung damage and why funding stem cell research is so vital. 6 October is International Stem Cell Awareness Day. UCL Centre for Stem Cells and Regenerative Medicine: http://www.ucl.ac.uk/stemcells/ For UCL lectures on stem cell research (link to iTunesU): http
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Chemical and Environmental Behaviour of Materials: Fuel Cells
This set of animations demonstrates the principles of a solid oxide fuel cell and a proton exchange membrane cell. From TLP: Fuel Cells
Author(s): Derek Fray, University of Cambridge,Steve Mounsey,

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Douglas Melton, Harvard University: "Stem Cell Challenges in Biology and Public Policy" - April 10,
Douglas Melton will discuss the biology and public policy challenges surrounding stem cell research. The potential of human embryonic stem cells for understanding human development and finding new therapies will be presented. Dr. Melton is a cell and molecular biologist as well as an advocate of embryonic stem cell research. His research focuses on the developmental biology of the pancreas. One of the primary goals of his work is to understand how human embryonic stem cells differentiate into pa
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Virtual laboratories in Molecular and Cell Biology - Immuno-electron-microscopy
A virtual laboratory that includes immuno-gold labelling and transmission electron micrography (immuno-EM). It allows the student to study intracellular-traffic pathways of two cell-surface receptor molecules, following stimulation of the cells with their specific ligand, for different time periods. The programme first introduces the theory underlying the techniques and includes a video of EM work in a real laboratory. The student is then taken through a series of questions which requires them t
Author(s): David Male, Ignacio Romero, Jane Loughlin - The Op

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Virtual laboratories in Molecular and Cell Biology - SDS-PAGE
A protein analysis laboratory using SDS-PAGE, western-blotting and endoprotease digestion. The programme includes a section on the theory of the techniques, a video demonstration in a real laboratory, and a series of questions which guide the students through the structural analysis of model proteins (3 are included). Students go to the virtual laboratory and devise their own experiments in order to determine the molecular weight, subunit composition etc of the proteins. Results (gels and blots)
Author(s): David Male, Ignacio Romero, Jane Loughlin - The Op

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5.4 Inspiratory drive

The supply of oxygen to tissues such as the heart, liver and WAT is, under euthermic conditions, invariably linked to and dependent upon local blood flow and pulmonary function. However, as we have already seen, under conditions in which blood flow is reduced to a trickle, the control of energy supply switches to local adaptations in the capillaries and tissue cells, including the oxygen affinity of erythrocyte haemoglobin, the supply and metabolism of respiratory fuels and the rate of protei
Author(s): The Open University

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Interdisciplinary Science Nanoscale Frontiers Student Document
In this module you will explore basic cell biology and cell imaging techniques. using quantum dots. You will also be introduced to the flow of genetic information through the cell, whereby the DNA inherited by an organism leads to specific traits by dictating the synthesis of proteins.
Author(s): Chris Willmott,Mervyn Roy,Derek Raine

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Low magnification SEM image of open cell polyurethane foam
If a gas is injected into a liquid it forms a cellular foam structure. When a thermoset prepolymer of low viscosity is foamed, the polymer can drain from the cell walls (driven by surface tension) before it sets at the cell edges, leaving an open-celled foam. The cell edges have three concave sides, giving rise to the tri-cuspid cross section visible at the bottom of this image. The average co-ordination number for the nodes (where struts meet) is four, giving tetrahedral junctions.
Author(s): Dr J A Elliott, Department of Materials Science an

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X-ray tomography image of open cell polyurethane foam
If a gas is injected into a liquid it forms a cellular foam structure. When a thermoset prepolymer of low viscosity is foamed, the polymer can drain from the cell walls (driven by surface tension) before it sets at the cell edges, leaving an open-celled foam. The cell edges have three concave sides. The average co-ordination number for the nodes (where struts meet) is four, giving tetrahedral junctions. The deformation behaviour of the foam was observed by X-ray microtomography at the ESRF in Gr
Author(s): Dr J A Elliott, Department of Materials Science an

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Open celled aluminium foam produced by infiltration of sintered salt
This is an inexpensive route for the production of open celled foams. It allows a high degree of control over cell size and shape, and results in relatively uniform morphology. The interconnectivity of pores can be controlled by varying the degree of sintering of the precursor.
Author(s): J A Curran, Department of Materials Science and Me

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Fe, C 1.0 (wt%), hypereutectoid alloy
This secondary electron SEM image shows the cementite delineating prior austenite grain boundaries with a thin layer. The amount of proeutectoid phase is very low, with the majority of the area being taken by the pearlite eutectoid. Again each pearlite cell has a different orientation with the ferrite phase being selectively etched.
Author(s): Prof T W Clyne, Department of Materials Science an

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