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Ingrid Dreveny

Assistant Professor in Protein Crystallography, Faculty of Science

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Biography

I received my training as a chemist at the University of Graz. As a Masters student at the University Louis Pasteur, Strasbourg, I studied the folding and structure of synthetic peptides. This work sparked my interest and fascination for protein structure from which I pursued a Ph.D. in protein crystallography under the supervision of Christoph Kratky, working on the structure and mechanism of an unusual flavoprotein that has wide-ranging applications in industrial biocatalysis.

During my postdoctoral years at Imperial College London in the laboratory of Paul Freemont and Xiaodong Zhang I uncovered how the multi-functional molecular machine, the AAA ATPase p97, that has been associated with neurodegenerative diseases and cancer, recognizes adaptor proteins. After a brief period as research fellow in the School of Pharmacy, University of Nottingham, I was appointed lecturer in protein crystallography.

Research Summary

I am interested in how macromolecular structure determines function and can help explain cellular events. My main area of expertise is macromolecular X-ray crystallography, which I combine with other… read more

Recent Publications

Current Research

I am interested in how macromolecular structure determines function and can help explain cellular events. My main area of expertise is macromolecular X-ray crystallography, which I combine with other biophysical and biochemical techniques. My research is aimed at:

  • Establishing protein structure - function relationships
  • Characterising protein-protein and protein-ligand interactions
  • Uncovering the molecular basis of human diseases

Current research topics include:

  • Structure and function of proteases in the ubiquitin pathway
  • Molecular mechanism of enzymes in posttranslational modification pathways
  • Protein complexes in ciliary trafficking
  • Enzymes for pharmaceutical applications

For further details please visit the Structural Biology group website.

Memberships of Committees & Professional Bodies

Biochemical Society; British Crystallographic Association

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

For all enquiries please visit:
www.nottingham.ac.uk/enquiry