Jing Yang

Contact

• workRoom C28 Boots Science Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 8466276
• jing.yang@nottingham.ac.uk

Biography

• 1999-2003, BEng, Material Science and Engineering - Central South University, China.
• 2003-2007, PhD - Preparation and characterisation of a resorbable phosphate glass fibre reinforced Poly(ε-caprolactone) composite. School of Mechanical, Material and Manufacturing Engineering, University of Nottingham.
• 2007 Feb.- Postdoctoral Research Fellow: Laboratory of Biophysics and Surface Analysis (LBSA), School of Pharmacy, University of Nottingham.

Research Summary

My general research interest is to study interactions of material surfaces, biomolecules and biological activities. I am currently working on a Wellcome Trust funded project which aims to find… read more

Selected Publications

• MEI, Y., SAHA, K., BOGATYREV, S.R., YANG, J., HOOK, A.L., KALCIOGLU, I., CHO, S-W., MITALIPOVA, M., PYZOCHA, N., ROJAS, F., VAN VLIET, K.J., DAVIES, M.C., ALEXANDER, M.R., LANGER, R., JAENISCH, R. and AN, 2010. Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells Nature Materials. 9(9), 768-778
• YANG, J., ROSE, F.R.A.J., GADEGAARD, N. and ALEXANDER, M.R., 2009. A high-throughput assay of cell-surface interactions using topographical and chemical gradients. Advanced Materials. 21(3), 300-304
• YANG, J., MEI, Y., HOOK, A.L., TAYLOR, M., URQUHART, A.J., BOGATYREV, S.R., LANGER, R., ANDERSON, D.G., DAVIES, M.C. and ALEXANDER, M.R., 2010. Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays Biomaterials. 31(34), 8827-8838
• YANG, J., ROSE, F.R.A.J., GADEGAARD, N. and ALEXANDER, M.R., 2009. The effect of sessile drop volume on the wetting anisotropy observed on grooved surfaces Langmuir. 25, 2567-2571

• View all publications

Current Research

My general research interest is to study interactions of material surfaces, biomolecules and biological activities. I am currently working on a Wellcome Trust funded project which aims to find anti-bacterial polymers using high throughput approaches. My work concentrates on high throughput characterisation of polymer surfaces, and identification of correlations between polymer surface properties and bacterial responses. I use a range of techniques including ToF SIMS, XPS, water contact angle measurement, AFM, Raman, etc. to measure surface and bulk properties. Chemometric methods, such as PCA and PLS regression, are used to identify correlation between surface properties and bacterial response.

My previous research included studying activities of mammalian cells on chemically and topographically patterned surfaces, wetting phenomenon on patterned surfaces and mechanical properties of absorbable fibre reinforced polymers. I worked with collaborators from different backgrounds, such as cell biology, chemistry, physics, engineering; and different institutes e.g. MIT, Glasgow University.

• DAVIES M.C., ALEXANDER M.R., HOOK A.L., YANG J., MEI Y., TAYLOR M., URQUHART A.J., LANGER R and ANDERSON D.G., 2010. High throughput surface characterization: A review of a new tool for screening prospective biomedical material arrays Journal of Drug Targeting. 18(10), 741-751
• YANG, J., MEI, Y., HOOK, A.L., TAYLOR, M., URQUHART, A.J., BOGATYREV, S.R., LANGER, R., ANDERSON, D.G., DAVIES, M.C. and ALEXANDER, M.R., 2010. Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays Biomaterials. 31(34), 8827-8838
• YANG, J. and ALEXANDER M.R., 2010. Techniques for analysing biomaterial surface chemistry. In: WILLIAMS, R., ed., Surface Modification of Biomaterials: Methods, Analysis and Applications Cambridge: Woodhead. (In Press.)
• MEI, Y., SAHA, K., BOGATYREV, S.R., YANG, J., HOOK, A.L., KALCIOGLU, I., CHO, S-W., MITALIPOVA, M., PYZOCHA, N., ROJAS, F., VAN VLIET, K.J., DAVIES, M.C., ALEXANDER, M.R., LANGER, R., JAENISCH, R. and AN, 2010. Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells Nature Materials. 9(9), 768-778
• YANG, J., ROSE, F.R.A.J., GADEGAARD, N. and ALEXANDER, M.R., 2009. A high-throughput assay of cell-surface interactions using topographical and chemical gradients. Advanced Materials. 21(3), 300-304
• YANG, J., ROSE, F.R.A.J., GADEGAARD, N. and ALEXANDER, M.R., 2009. The effect of sessile drop volume on the wetting anisotropy observed on grooved surfaces Langmuir. 25, 2567-2571