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School of Biomedical Sciences
   
   
  

Metabolic physiology

The Importance of Research in Metabolic Physiology

It is now acknowledged that although animals share genes, organ systems and systemic physiology with humans, humans differ significantly in terms of morphometry, physiology and life span. Therefore, it is only logical that to gain detailed insight into human health and disease, we must ultimately study humans, and use animal and cell based approaches to support and provide scientific justification for investigations in man.

 

Our Research Interests in Metabolic Physiology

The research goal of the Metabolic Physiology group is to use such an integrative approach to further our understanding of the regulation of metabolism and its dysfunction in disease. Colleagues within the group cover the range of expertise and techniques necessary to perform detailed, integrated metabolic investigations in healthy human volunteers and patients, and to dovetail these with relevant animal, cell and and molecular biological approaches, enabling truly translational research.  The group has an international research standing in the area of human nutrition, the control and integration of fuel utilisation in health and disease, such as in obesity, and the regulation of muscle mass during exercise, inactivity and disease.  The group is funded by industry, research charities and research councils, and delivers the School’s MSc in Integrative Physiology in Health and Disease .

For more information, please email Professor Paul Greenhaff .

See research degree opportunities related to this group .

 

Group Publications

Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans

Description
J Physiol; Wall, B.T., Stephens, F.B., Constantin-Teodosiu, D., Marimuthu, K., Macdonald, I.A., and Greenhaff, P.L.

Applications of multi-nuclear magnetic resonance spectroscopy at 7T

Description
World J Radiol; Stephenson, M.C., Gunner, F., Napolitano, A., Greenhaff, P.L., Macdonald, I.A., Saeed, N., Vennart, W., Francis, S.T., and Morris, P.G.

Increased expression of hepcidin and toll-like receptors 8 and 10 in viral keratitis

Description
Cornea; Mohammed, I., Abedin, A., Tsintzas, K., Abedin, S.A., Otri, A.M., Hopkinson, A., Mathew, M., and Dua, H.S.

Public health initiatives in obesity prevention: the need for evidence-based policy

Description
Int J Obes (Lond); Macdonald, I.A. and Atkinson, R.
 
 

School of Biomedical Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham, NG7 2UH

telephone: +44 (0) 115 823 0141
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