Institute of Genetics

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Liz Bailes

Overview Research Publications Opportunities

Research Lecturer (Institute Member)

Room: D102 (Medical School)

Address: Institute of Genetics, The University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, UK

Tel: +44 (0)115 823 0336 (int 30336)
Fax: 0115 823 0338
Email: liz.Bailes@nottingham.ac.uk

Research Overview:

I study molecular evolution using computer-based analyses of gene and genome sequences. My work has been on the evolution of bacteria and viruses. Analyses of bacterial genomes provide insights into the mutational and selective forces shaping them; a particular focus is the evolution of patterns of biased usage of alternative synonymous codons. Analyses of viruses are aimed at understanding the origins of genetic diversity in different viral groups. My work has mostly been on the origins and evolution of AIDS viruses.

Education, appointments and honours

PhD 2001 University of Nottingham
B.Sc. Hons. first class 1995 genetics University of Nottingham
B.Sc. Hons. upper second 1971 chemical physics University of Sussex

Posts

2001-2005, Senior research fellow Institute of Genetics, University of Nottingham
2005-present, Research Lecturer Institute of Genetics, University of Nottingham.

Selected Publications

  • BAILES, E., GAO, F., BIBOLLET-RUCHE, F., COURGNAUD, V., PEETERS, M., MARX, P.A., HAHN, B.H. and SHARP, P.M., 2003. Hybrid origin of SIV in chimpanzees. Science, 300(5626), 1713-1714.
  • KEELE, B.F., VAN HEUVERSWYN, F., LI, Y., BAILES, E., TAKEHISA, J., SANTIAGO, M.L., BIBOLLET-RUCHE, F., CHEN, Y., WAIN, L.V., LIEGEOIS, F., LOUL, S., NGOLE, E.M., BIENVENUE, Y., DELAPORTE, E., BROOKFIELD, J.F.Y., SHARP, P.M., SHAW, G.M., PEETERS, M. and HAHN,, 2006. Chimpanzee reservoirs of pandemic and nonpandemic HIV-1. Science, 313(5786), 523-526.
  • VAN HEUVERSWYN, F., LI, Y., NEEL, C., BAILES, E., KEELE, B.F., LIU, W., LOUL, S., BUTEL, C., LIEGEOIS, F., BIENVENUE, Y., NGOLLE, E.M., SHARP, P.M., SHAW, G.M., DELAPORTE, E., HAHN, B.H. and PEETERS, M., 2006. SIV infection in wild gorillas. Nature, 444(7116), 164.
  • SANTIAGO, M.L., RANGE, F., KEELE, B.F., LI, Y., BAILES, E., BIBOLLET-RUCHE, F., FRUTEAU, C., NOë, R., PEETERS, M., BROOKFIELD, J.F.Y., SHAW, G.M., SHARP, P.M. and HAHN, B.H., 2005. Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2. Journal of Virology, 79(19), 12515-12527.
  • BAILES,E., CHAUDHURI,R.R., SANTIAGO,M.L., BIBOLLET-RUCHE,F., HAHN,B.H. and SHARP,P., 2002. The evolution of primate lentiviruses and the origins of AIDS. In: LEITNER,T., ed. The Molecular Epidemiology of Human Viruses. Boston; Kluwer Academic, pp. 65-96
  • SHARP, P.M., BAILES, E., CHAUDHURI, R.R., RODENBURG, C.M., SANTIAGO, M.O. and HAHN, B.H., 2001. The origins of acquired immune deficiency syndrome viruses: where and when?. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 356(1410), 867-876.
  • SHARP, P.M., BAILES, E., GROCOCK, R.J., PEDEN, J.F. and SOCKETT, R.E., 2005. Variation in the strength of selected codon usage bias among bacteria. Nucleic Acids Research, 33(4), 1141-1153.

Group Members

Li Li Postgraduate Student +44 (0)115 823 0374
internal (QMC) 30377		 D119
Anoop Arya Postgraduate Student +44(0)115 8230329
internal (QMC) 30329		 C27