MCNAUGHTON D, KNIGHT W, GUERREIRO R, RYAN N, LOWE J, POULTER M, NICHOLL DJ, HARDY J, REVESZ T, LOWE J, ROSSOR M, COLLINGE J and MEAD S, 2012. Duplication Of Amyloid Precursor Protein (App), But Not Prion Protein (Prnp) Gene Is A Significant Cause Of Early Onset Dementia In A Large Uk Series. Neurobiology Of Aging. 33(2), 426.e13-21 KILDAY J, MITRA B, DOMERG C, WARD J, ANDREIUOLO F, OSTESO-IBANEZ T, MAUGUEN A, VARLET P, LE DELEY M, LOWE J, ELLISON DW, GILBERTSON RJ, COYLE B, GRILL J and GRUNDY RG, 2012. Copy Number Gain Of 1Q25 Predicts Poor Progression-Free Survival For Pediatric Intracranial Ependymomas And Enables Patient Risk Stratification. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research. (In Press.)
BARROW, JENNIFER, ADAMOWICZ-BRICE, MARTYNA, CARTMILL, MARIA, MACARTHUR, DONALD, LOWE, JAMES, ROBSON, KEITH, BRUNDLER, MARIE-ANNE, WALKER, DAVID A, COYLE, BETH and GRUNDY, RICHARD, 2011. Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas. Neuro-oncology. 13(2), 212-22 BEDFORD, LYNN, LOWE, JAMES, DICK, LAWRENCE R, MAYER, R JOHN and BROWNELL, JAMES E, 2011. Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets. Nature reviews. Drug discovery. 10(1), 29-46 ALOMAR, THAER S, NUBILE, MARIO, LOWE, JAMES and DUA, HARMINDER S, 2011. Corneal intraepithelial neoplasia: in vivo confocal microscopic study with histopathologic correlation. American journal of ophthalmology. 151(2), 238-47 MILLER, SUZANNE, ROGERS, HAZEL A, LYON, PAUL, RAND, VIKKI, ADAMOWICZ-BRICE, MARTYNA, CLIFFORD, STEVEN C, HAYDEN, JAMES T, DYER, SARA, PFISTER, STEFAN, KORSHUNOV, ANDREY, BRUNDLER, MARIE-ANNE and LOWE, JA, 2011. Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma. Neuro-oncology. 13(8), 866-79 ALOMAR TS, AL-AQABA M, GRAY T, LOWE J and DUA HS, 2011. Histological And Confocal Microscopy Changes In Chronic Corneal Edema: Implications For Endothelial Transplantation. Investigative Ophthalmology & Visual Science. 52(11), 8193-207 AL-AQABA M, ALOMAR T, LOWE J and DUA HS, 2011. Corneal Nerve Aberrations In Bullous Keratopathy. American Journal Of Ophthalmology. 151(5), 840-849.e1 RATTRAY, IVAN, PITIOT, ALAIN, LOWE, JAMES, AUER, DOROTHEE P, LIMA, SARAH-JANE, SCHUBERT, MIRJAM I, PRIOR, MALCOLM J W, MARSDEN, CHARLES A, DIAZ, FERNANDO PÉREZ, KENDALL, DAVID A and PARDON, MARIE-CH, 2010. Novel cage stress alters remote contextual fear extinction and regional T2 magnetic resonance relaxation times in TASTPM mice overexpressing amyloid. Journal of Alzheimer's disease : JAD. 20(4), 1049-68 PAUGH, BARBARA S, QU, CHUNXU, JONES, CHRIS, LIU, ZHAOLI, ADAMOWICZ-BRICE, MARTYNA, ZHANG, JUNYUAN, BAX, DORINE A, COYLE, BETH, BARROW, JENNIFER, HARGRAVE, DARREN, LOWE, JAMES, GAJJAR, AMAR and ZHAO, WEI, 2010. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(18), 3061-8 HAINSWORTH AH, ALLSOPP RC, JIM A, POTTER JF, LOWE J, TALBOT CJ and PRETTYMAN RJ, 2010. Death-Associated Protein Kinase (Dapk1) In Cerebral Cortex Of Late-Onset Alzheimer's Disease Patients And Aged Controls. Neuropathology And Applied Neurobiology. 36(1), 17-24 AL-AQABA MA, FARES U, SULEMAN H, LOWE J and DUA HS, 2010. Architecture And Distribution Of Human Corneal Nerves. The British Journal Of Ophthalmology. 94(6), 784-9 TALLANTYRE EC, BØ L, AL-RAWASHDEH O, OWENS T, POLMAN CH, LOWE JS and EVANGELOU N, 2010. Clinico-Pathological Evidence That Axonal Loss Underlies Disability In Progressive Multiple Sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 16(4), 406-11 BÄUMER D, HILTON D, PAINE SML, TURNER MR, LOWE J, TALBOT K and ANSORGE O, 2010. Juvenile Als With Basophilic Inclusions Is A Fus Proteinopathy With Fus Mutations. Neurology. 75(7), 611-8 ALCOCK, JOELLE, LOWE, JAMES, ENGLAND, TIM, BATH, PHILIP and SOTTILE, VIRGINIE, 2009. Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex. Neuroscience Letters. 450(2), 114-6 TALLANTYRE, EMMA C, PAINE, SIMON M L, SHARP, COLIN P, LOWE, JAMES S and GRAN, BRUNO, 2009. Atypical progressive multifocal leukoencephalopathy associated with an unusual JC polyomavirus mutation. Archives of Neurology. 66(8), 1021-4
TALLANTYRE, E C, BØ, L, AL-RAWASHDEH, O, OWENS, T, POLMAN, C H, LOWE, J and EVANGELOU, N, 2009. Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease. Brain : a journal of neurology. 132(Pt 5), 1190-9
ROGERS, H A, MILLER, S, LOWE, J, BRUNDLER, M-A, COYLE, B and GRUNDY, R G, 2009. An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET). British journal of cancer. 100(8), 1292-302
PAINE, S, BEDFORD, L, THORPE, JR, MAYER, RJ, CAVEY, JR, BAJAJ, N, SHEPPARD, PW, LOWE, J, LAYFIELD, R, 2009. Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration. Neuroscience Letters. 460(3), 205-8 KILDAY, JOHN-PAUL, RAHMAN, RUMAN, DYER, SARA, RIDLEY, LEE, LOWE, JAMES, COYLE, BETH and GRUNDY, RICHARD, 2009. Pediatric ependymoma: biological perspectives. Molecular cancer research : MCR. 7(6), 765-86
SAID, DALIA G, NUBILE, MARIO, ALOMAR, THAER, HOPKINSON, ANDY, GRAY, TREVOR, LOWE, JAMES and DUA, HARMINDER S, 2009. Histologic features of transplanted amniotic membrane: implications for corneal wound healing. Ophthalmology: the Journal of the American Academy of Ophthalmology. 116(7), 1287-95
GILMORE, C P, DONALDSON, I, BÖ, L, OWENS, T, LOWE, J and EVANGELOU, N, 2009. Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord. Journal of neurology, neurosurgery, and psychiatry. 80(2), 182-7
PARDON,MC, SARMAD,S, RATTRAY,I, BATES,TE, SCULLION,GA, MARSDEN,CA, BARRETT,DA, LOWE,J and KENDALL, DA, 2009. Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of aging. BEDFORD L, PAINE S, REZVANI N, MEE M, LOWE J and MAYER RJ, 2009. The Ups And Autophagy In Chronic Neurodegenerative Disease: Six Of One And Half A Dozen Of The Other--Or Not? Autophagy. 5(2), 224-7
BEDFORD, L, HAY, D, DEVOY, A, PAINE, S, POWE, D G, SETH, R, GRAY, T, TOPHAM, I, FONE, K, REZVANI, N, MEE, M, SOANE, T, LAYFIELD, R and SHEPPARD, P W, 2008. Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies. Journal of Neuroscience. 28, 8189-98 RIDLEY, LEE, RAHMAN, RUMAN, BRUNDLER, MARIE-ANNE, ELLISON, DAVID, LOWE, JAMES, ROBSON, KEITH, PREBBLE, EMMA, LUCKETT, INGA, GILBERTSON, RICHARD J, PARKES, SHEILA, RAND, VIKKI, COYLE, BETH and GRUNDY, RIC, 2008. Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma. Neuro-oncology. 10(5), 675-89 HOPKINSON, ANDREW, SHANMUGANATHAN, VIJAY A, GRAY, TREVOR, YEUNG, AARON M, LOWE, JAMES, JAMES, DAVID K and DUA, HARMINDER S, 2008. Optimization of amniotic membrane (AM) denuding for tissue engineering. Tissue engineering. Part C, Methods. 14(4), 371-81 SAID, DALIA G, MATHEW, MANU, SHAIKH, M YUSUF, MAHARAJAN, V SENTHIL, LOWE, JAMES and DUA, HARMINDER S, 2008. Diffuse keratoconjunctival proliferation: a novel clinical manifestation. Archives of ophthalmology. 126(9), 1226-32
BEDFORD, LYNN, HAY, DAVID, PAINE, SIMON, REZVANI, NOOSHIN, MEE, MAUREEN, LOWE, JAMES and MAYER, R JOHN, 2008. Is malfunction of the ubiquitin proteasome system the primary cause of alpha-synucleinopathies and other chronic human neurodegenerative disease? Biochimica et Biophysica Acta. 1782(12), 683-90
GILMORE,, DELUCA,, BÖ,, OWENS,, LOWE,, ESIRI, and EVANGELOU,, 2008. Spinal Cord Neuronal Pathology in Multiple Sclerosis. Brain pathology (Zurich, Switzerland).
CAIRNS, N.J., BIGIO, E.H., MACKENZIE, I.R.A., NEUMANN, M., LEE, V.M.-Y., HATANPAA, K.J., WHITE, C.L., SCHNEIDER, J.A., GRINBERG, L.T., HALLIDAY, G., DUYCKAERT, C., LOWE, J.S., HOLM, I.E., TOLNAY, M., OKAMOTO, K., YOKOO, H., MURAYAMA, S., WOULFE, J., MUNOZ, D.G., DICKSON, D.W., INCE, P.G., TROJANOWSKI, J.Q. and MANN, D.M.A., 2007. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration Acta neuropathologica. 114(1), 5-22 ALTAF, N., DANIELS, L., MORGAN, P.S., LOWE, J., GLADMAN, J., MACSWEENEY, S.T., MOODY, A. and AUER, D.P., 2006. Cerebral white matter hyperintense lesions are associated with unstable carotid plaque European Journal of Vascular and Endovascular Surgery. 31(1), 8-13 GILMORE, C.P., BÖ, L., OWENS, T., LOWE, J., ESIRI, M.M. and EVANGELOU, N., 2006. Spinal cord gray matter demyelination in multiple sclerosis-a novel pattern of residual plaque morphology Brain Pathology. 16(3), 202-208 SHANMUGANATHAN,V.A., FOSTER,T., KULKARNI,B.B., HOPKINSON,A., GRAY,T., POWE,D.G., LOWE,J. and DUA,H.S, 2006. Morphological Characteristics of the Limbal Epithelial Crypt British Journal of Ophthalmology. 91, 514-519 DUA, H. S., LAGNADO, R., RAJ, D., SINGH, R., MANTRY, S., GRAY, T. and LOWE, J., 2006. Alcohol Delamination of the Corneal Epithelium: An Alternative in the Management of Recurrent Corneal Erosions Ophthalmology: the Journal of the American Academy of Ophthalmology. VOL 113(NUMBER 3), 404-411 SHASTRI-HURST, N, TSEGAYE, M, ROBSON, D K, LOWE, J S and MACARTHUR, D C, 2006. Stereotactic brain biopsy: An audit of sampling reliability in a clinical case series. British Journal of Neurosurgery. 20(4), 222-6 YOUNG, B. LOWE, J. STEVENS, A, HEATH, JW., 2006. Functional Histology: A Text and Colour Atlas 5th. Churchill Livingstone, Elsevier.
MCKEITH, I.G., DICKSON, D.W., LOWE, J., EMRE, M., O'BRIEN, J.T., FELDMAN, H., CUMMINGS, J., DUDA, J.E., LIPPA, C., PERRY, E.K., AARSLAND, D., ARAI, H., BALLARD, C.G., BOEVE, B., BURN, D.J., COSTA, D., DEL SER, T., DUBOIS, B., GALASKO, D., GAUTHIER, S., GOETZ, C.G., GOMEZ-TORTOSA, E., HALLIDAY, G., HANSEN, L.A., HARDY, J., IWATSUBO, T., KALARIA, R.N., KAUFER, D., KENNY, R.A., KORCZYN, A., KOSAKA, K., LEE, V.M.Y., LEES, A., LITVAN, I., LONDOS, E., LOPEZ, O.L., MINOSHIMA, S., MIZUNO, Y., MOLINA, J.A., MUKAETOVA-LADINSKA, E.B., PASQUIER, F., PERRY, R.H., SCHULZ, J.B., TROJANOWSKI, J.Q. and YAMADA, M., 2005. Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium Neurology. 65(12), 1863-1872 GILMORE, C.P, DELUCA, G.C, BÖ, L., OWENS, T., LOWE, J., ESIRI, M. and EVANGELOU, N., 2005. Spinal cord atrophy in multiple sclerosis caused by white matter volume loss. Archives of Neurology. 62(12), 1859-62 LOWE, JAMES, HAND, NEIL and MAYER, R JOHN, 2005. Application of ubiquitin immunohistochemistry to the diagnosis of disease. Methods in enzymology.. 399, 86-119
STEVENS, ALAN AND LOWE, JAMES, 2005. Human Histology 3rd. Elsevier, Mosby.
LAYFIELD, ROBERT, LOWE, JAMES and BEDFORD, LYNN, 2005. The ubiquitin-proteasome system and neurodegenerative disorders. Essays in Biochemistry. 41, 157-71
WOOD-ALLUM, C., BRENNAN, P., HEWITT, M., LOWE, J., TYFIELD, L. and WILLS, A., 2004. Clinical and histopathological heterogeneity in patients with 4q35 facioscapulohumeral muscular dystrophy (FSHD) Neuropathology and Applied Neurobiology. VOL 30(NUMBER 2), 188-191 SHAHRIZAILA, N., LOWE, J. and WILLS, A., 2004. Familial myopathy with tubular aggregates associated with abnormal pupils Neurology. VOL 63(NUMB 6), 1111-1113
ELLISON, D. LOVE, S. CHIMELLI, L. HARDING, B. LOWE, J. VINTERS, H., 2004. Neuropathology: A Reference Text of CNS Pathology 2nd. Mosby.
GRAEBER, M. B., LOWE, J. and RADOTRA, B., 2004. A Free Community Approach to Classifying Disease PLOS Medicine. VOL 1(NUMB 2), 113-114 MURPHY, R.E., MOODY, A.R., MORGAN, P.S., MARTEL, A.L., DELAY, G.S., ALLDER, S., MACSWEENEY, S.T., TENNANT, W.G., GLADMAN, J., LOWE, J. and HUNT, B.J., 2003. Prevalence of complicated carotid atheroma as detected by magnetic resonance direct thrombus imaging in patients with suspected carotid artery stenosis and previous acute cerebral ischemia. Circulation (Baltimore). 107(24), 3053-58 LAYFIELD, ROBERT, CAVEY, JAMES R and LOWE, JAMES, 2003. Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders. Ageing Research Reviews. 2(4), 343-56 LOWE, J AND ROSSOR, M, 2003. Frontotemporal Lobar Degeneration. In: DICKSON, D, ed., Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders ISN Press. 342 - 348
BALL, G., MIAN, S., HOLDING, F., ALLIBONE, R. O., LOWE, J., ALI, S., LI, G., MCCARDLE, S., ELLIS, I. O. and CREASER, C., 2002. An integrated approach utilizing artificial neural networks and SELDI mass spectrometry for the classification of human tumours and rapid identification of potential biomarkers Bioinformatics. VOL 18(PART 3), 395-404 ACHIM, CRISTIAN, AUER, ROLAND, BERGERON, CATHERINE, CARDOZO, ADRIANA, DEPREZ, MANUEL, DE VOS, ROB, DUYCKAERTS, CHARLES, EGENSPERGER, RUPERT, ESIRI, MARGARET, FROSCH, MATTHEW P, GIANNINI, CATERINA and GOE, 2002. Global democratic consensus on neuropathological disease criteria. Lancet neurology.. 1(6), 340
STEVENS, A, LOWE, J. YOUNG, B., 2002. Basic Histopathology Churchill Livingstone.
CARTMILL, M., HEWITT, M., WALKER, D., LOWE, J., JASPAN, T. and PUNT, J., 2001. The use of chemotherapy to facilitate surgical resection in pleomorphic xanthoastrocytoma: experience in a single case Child's Nervous System. VOL 17(PART 9), 563-566 BUTLER, T. K. H., DUA, H. S., EDWARDS, R. and LOWE, J. S., 2001. In Vitro Model of Infectious Crystalline Keratopathy: Tissue Architecture Determines Pattern of Microbial Spread Investigative Ophthalmology and Visual Science. VOL 42(PART 6), 1243-1246
LOWE, J, MAYER, J, LANDON, M and LAYFIELD, R, 2001. Ubiquitin and the molecular pathology of neurodegenerative diseases. Advances in Experimental Medicine and Biology. 487, 169-86
JONES, N., SVIRIDOV, A., SOBOL, E., OMELCHENKO, A. and LOWE, J., 2001. A Prospective Randomised Study of Laser Reshaping of Cartilage In Vivo Lasers in Medical Science. VOL 16(PART 4), 284-290 LAYFIELD, R, ALBAN, A, MAYER, R J and LOWE, J, 2001. The ubiquitin protein catabolic disorders. Neuropathology and Applied Neurobiology. 27(3), 171-9 STEVENS, ALAN AND LOWE, JAMES, 2000. Pathology 2nd. Mosby.
FERGUSSON, J, LANDON, M, LOWE, J, WARD, L, VAN LEEUWEN, F W and MAYER, R J, 2000. Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin-B protein. Neuroscience Letters. 279(2), 69-72 TILLEY, L., MORGAN, K., GRAINGER, J., MARSTERS, P., MORGAN, L., LOWE, J., XUEREB, J., WISCHIK, C., HARRINGTON, C. and KALSHEKER, N., 1999. Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease European Journal of Human Genetics. VOL 7(NUMBER 6), 659-663 LOWE, J., 1998. Establishing a Pathological Diagnosis in Degenerative Dementias Brain Pathology. VOL 8(NUMBER 2), 403-406
INCE, P. G., LOWE, J. and SHAW, P. J., 1998. Review. Amyotrophic lateral sclerosis: current issues in classification, pathogenesis and molecular pathology Neuropathology and Applied Neurobiology. VOL 24(NUMBER 2), 104-117 ARNOLD, J, DAWSON, S, FERGUSSON, J, LOWE, J, LANDON, M and MAYER, R J, 1998. Ubiquitin and its role in neurodegeneration. Progress in Brain Research. 117, 23-34
MORGAN, K., MORGAN, L., CARPENTER, K., LOWE, J., LAM, L., CAVE, S., XUEREB, J., WISCHIK, C., HARRINGTON, C. and KALSHEKER, N. A., 1997. Microsatellite polymorphism of the à~1-antichymotrypsin gene locus associated with sporadic Alzheimer's disease Human Genetics. VOL 99(NUMBER 1), 27-31 LENNOX, G G and LOWE, J S, 1997. Dementia with Lewy bodies. Baillière's clinical neurology.. 6(1), 147-66
LOWE, J and DICKSON, D, 1997. Pathological diagnostic criteria for dementia associated with cortical Lewy bodies: review and proposal for a descriptive approach. Journal of neural transmission. Supplementum.. 51, 111-20
MCKEITH, I G, GALASKO, D, KOSAKA, K, PERRY, E K, DICKSON, D W, HANSEN, L A, SALMON, D P, LOWE, J, MIRRA, S S, BYRNE, E J, LENNOX, G, QUINN, N P, EDWARDSON, J A, INCE, P G, BERGERON, C, BURNS, A and MILLE, 1996. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 47(5), 1113-24
LOWE, J, MCDERMOTT, H, LOEB, K, LANDON, M, HAAS, A L and MAYER, R J, 1995. Immunohistochemical localization of ubiquitin cross-reactive protein in human tissues. Journal of Pathology. 177(2), 163-9 COOPER, P N, JACKSON, M, LENNOX, G, LOWE, J and MANN, D M, 1995. Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia. Archives of Neurology. 52(10), 1011-5
JACKSON, M, LENNOX, G, BALSITIS, M and LOWE, J, 1995. Lewy body dysphagia. Journal of Neurology, Neurosurgery and Psychiatry. 58(6), 756-8 MAYER, R J, LASZLO, L, LANDON, M, HOPE, J and LOWE, J, 1992. Ubiquitin, lysosomes, and neurodegenerative diseases. Annals of the New York Academy of Sciences. 674, 149-60 LOWE, J, FERGUSSON, J, KENWARD, N, LASZLO, L, LANDON, M, FARQUHAR, C, BROWN, J, HOPE, J and MAYER, R J, 1992. Immunoreactivity to ubiquitin-protein conjugates is present early in the disease process in the brains of scrapie-infected mice. Journal of Pathology. 168(2), 169-77 MAYER, R J, LASZLO, L, MIDDLETON, A, LANDON, M, HOPE, J and LOWE, J, 1992. Ubiquitin, lysosomes and neurodegenerative diseases. Biochemical Society Transactions. 20(3), 645-8
LáSZLó, L, DOHERTY, F J, WATSON, A, SELF, T, LANDON, M, LOWE, J and MAYER, R J, 1991. Immunogold localisation of ubiquitin-protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophils. FEBS Letters. 279(2), 175-8 MAYER, R J, LOWE, J, LANDON, M, MCDERMOTT, H, TUCKWELL, J, DOHERTY, F and LáSZLó, L, 1991. Ubiquitin and the lysosome system: molecular immunopathology reveals the connection. Biomedica biochimica acta.. 50(4-6), 333-41
LáSZLó, L, TUCKWELL, J, SELF, T, LOWE, J, LANDON, M, SMITH, S, HAWTHORNE, J N and MAYER, R J, 1991. The latent membrane protein-1 in Epstein-Barr virus-transformed lymphoblastoid cells is found with ubiquitin-protein conjugates and heat-shock protein 70 in lysosomes oriented around the microtubule organizing centre. Journal of Pathology. 164(3), 203-14 MAYER, R J, ARNOLD, J, LáSZLó, L, LANDON, M and LOWE, J, 1991. Ubiquitin in health and disease. Biochimica et Biophysica Acta. 1089(2), 141-57
LOWE, J, MCDERMOTT, H, LANDON, M, MAYER, R J and WILKINSON, K D, 1990. Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. Journal of Pathology. 161(2), 153-60 LOWE, J and MAYER, R J, 1990. Ubiquitin, cell stress and diseases of the nervous system. Neuropathology and Applied Neurobiology. 16(4), 281-91 BYRNE, E J, LENNOX, G, LOWE, J and REYNOLDS, G, 1990. Diffuse Lewy body disease: the clinical features. Advances in neurology.. 53, 283-6
LOWE, J, MCDERMOTT, H, KENWARD, N, LANDON, M, MAYER, R J, BRUCE, M, MCBRIDE, P, SOMERVILLE, R A and HOPE, J, 1990. Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice. Journal of Pathology. 162(1), 61-6 MAYER, R J, LOWE, J, LENNOX, G, LANDON, M, MACLENNAN, K and DOHERTY, F J, 1989. Intermediate filament-ubiquitin diseases: implications for cell sanitization. Biochemical Society symposium.. 55, 193-201
LENNOX, G, LOWE, J S, GODWIN-AUSTEN, R B, LANDON, M and MAYER, R J, 1989. Diffuse Lewy body disease: an important differential diagnosis in dementia with extrapyramidal features. Progress in clinical and biological research.. 317, 121-30
HEGGIE, P, BURDON, T, LOWE, J, LANDON, M, LENNOX, G, JEFFERSON, D and MAYER, R J, 1989. Ubiquitin gene expression in brain and spinal cord in motor neurone disease. Neuroscience Letters. 102(2-3), 343-8 LOWE, J, ALDRIDGE, F, LENNOX, G, DOHERTY, F, JEFFERSON, D, LANDON, M and MAYER, R J, 1989. Inclusion bodies in motor cortex and brainstem of patients with motor neurone disease are detected by immunocytochemical localisation of ubiquitin. Neuroscience Letters. 105(1-2), 7-13 LENNOX, G, LOWE, J, BYRNE, E J, LANDON, M, MAYER, R J and GODWIN-AUSTEN, R B, 1989. Diffuse Lewy body disease. Lancet. 1(8633), 323-4 MAYER, R J, LANDON, M, DOHERTY, F J, LOWE, J S, REYNOLDS, G P, BYRNE, E J, LENNOX, G G, JEFFERSON, D and GODWIN-AUSTEN, R B, 1989. Ubiquitin and dementia. Nature. 340(6230), 193 MAYER, R J, LOWE, J, LENNOX, G, DOHERTY, F and LANDON, M, 1989. Intermediate filaments and ubiquitin: a new thread in the understanding of chronic neurodegenerative diseases. Progress in clinical and biological research.. 317, 809-18
LENNOX, G, LOWE, J, LANDON, M, BYRNE, E J, MAYER, R J and GODWIN-AUSTEN, R B, 1989. Diffuse Lewy body disease: correlative neuropathology using anti-ubiquitin immunocytochemistry. Journal of Neurology, Neurosurgery and Psychiatry. 52(11), 1236-47 BYRNE, E J, LENNOX, G, LOWE, J and GODWIN-AUSTEN, R B, 1989. Diffuse Lewy body disease: clinical features in 15 cases. Journal of Neurology, Neurosurgery and Psychiatry. 52(6), 709-17 DOHERTY, F J, LASZLO, L, LOWE, J, LENNOX, G, LANDON, M and MAYER, R J, 1989. Ubiquitin-protein conjugates: clinical and experimental findings. Revisiones sobre biologÃa celular : RBC.. 20, 255-73
LENNOX, G, LOWE, J, MORRELL, K, LANDON, M and MAYER, R J, 1989. Anti-ubiquitin immunocytochemistry is more sensitive than conventional techniques in the detection of diffuse Lewy body disease. Journal of Neurology, Neurosurgery and Psychiatry. 52(1), 67-71 LOWE, J and MAYER, R J, 1989. Ubiquitin: new insights into chronic degenerative diseases. British Journal of Hospital Medicine. 42(6), 462-6
LOWE, J, BLANCHARD, A, MORRELL, K, LENNOX, G, REYNOLDS, L, BILLETT, M, LANDON, M and MAYER, R J, 1988. Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. Journal of Pathology. 155(1), 9-15 LENNOX, G, LOWE, J, MORRELL, K, LANDON, M and MAYER, R J, 1988. Ubiquitin is a component of neurofibrillary tangles in a variety of neurodegenerative diseases. Neuroscience Letters. 94(1-2), 211-7 LOWE, J, LENNOX, G, JEFFERSON, D, MORRELL, K, MCQUIRE, D, GRAY, T, LANDON, M, DOHERTY, F J and MAYER, R J, 1988. A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin. Neuroscience Letters. 94(1-2), 203-10 BYRNE, E J, LOWE, J, GODWIN-AUSTEN, R B, ARIE, T and JONES, R, 1987. Dementia and Parkinson's disease associated with diffuse cortical Lewy bodies. Lancet. 1(8531), 501