Centre for Mathematical Medicine and Biology

CMMB Publications

Below is a list of recent articles involving members of the CMMB. For further publications, please refer to the individual staff pages.

Coffee cup, books, pencil and paper



HILHORST, D, KAMPMANN, J, NGUYEN, TN and VAN DER ZEE, KG, 2015. Formal asymptotic limit of a diffuse-interface tumor-growth model. Mathematical Models and Methods in Applied Sciences. 25(6), 1011-1044.

PRATT, AC, WATTIS, JAD, SALTER, AM, 2015. Mathematical modelling of hepatic lipid metabolism. Mathematical Biosciences, 262, 167-181.



BARRACK, DS, THUL, R and OWEN, MR, 2014. Modelling the coupling between intracellular calcium release and the cell cycle during cortical brain development. Journal of Theoretical Biology, 347, 17-32.

BEGITT, A, DROESCHER, M, MEYER, T, SCHMID, CD, BAKER, M, ANTUNES, F, OWEN, MR, NAUMANN, R, DECKER, T and VINKEMEIER, U, 2014. STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling. Nature Immunology, 15(2), 168-176.

BESNARD, F, REFAHI, Y, MORIN, V, MARTEAUX, B, BRUNOUD, G, CHAMBRIER, P, ROZIER, F, MIRABET, V, LEGRAND, J, LAINE, S, THEVENON, E, FARCOT, E, CELLIER, C, DAS, P, BISHOPP, A, DUMAS, R, PARCY, F, HELARUITTA, Y, BOUDAOUD, A, GODIN, C, TRAAS, J, GUEDON, Y and VERNOUX, T, 2014. Cytokinin signalling inhibitory fields provide robustness to phylotaxis. Nature, 505(7483), 417-421.

BROOK, BS, 2014. Emergence of airway smooth muscle mechanical behaviour through dynamic reorganisation of contractile units and force transmission pathways. Journal of Applied Physiology. Online.

CHERNYAVSKY, IL, CROISIER, H, CHAPMAN, LAC, KIMPTON, LS, HIORNS, JE, BROOK, BS, JENSEN, OE, BILLINGTON, CK, HALL, IP and JOHNSON, SR, 2014. The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model. PLoS ONE 9(3), e90162.

GARG, VV, PRUDHOMME, S, VAN DER ZEE, KG and CAREY, GF, 2014. Adjoint-consistent formulations of slip models for coupled electroosmotic flow systems. Advanced Modeling and Simulation in Engineering, 2, 15.

HIORNS, JE, JENSEN, OE and BROOK, BS, 2014. Nonlinear compliance modulates dynamic bronchoconstriction in a multiscale airway model. Biophysical Journal, 107, 3030-3042.

HIRT, BV, PRESTON, S and WATTIS, JAD, 2014. Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs, Journal of Mathematical Biology, 68, 1521-1552.

MEIJER, HGE and COOMBES, S, 2014. Travelling waves in a neural field model with refractoriness. Journal of Mathematical Biology, 68(5), 1249-1268.

MEIJER, HGE and COOMBES, S, 2014. Travelling waves in models of neural tissue: from localised structures to periodic waves. EPJ Nonlinear Biomedical Physics, 2:3.

NOBLE, PB, PASCOE, CD, LAN, B, ITO, S, KISTEMAKER, LEM, TATLER, AL, PERA, T, BROOK, BS, GOSENS, R and WEST, AR, 2014. Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling. Pulmonary Pharmacology & Therapeutics. Online.

O'DEA, RD, NELSON, MR, EL HAJ, AJ, WATERS, SL and BYRNE, HM, 2014. A multiscale analysis of nutrient transport and biological tissue growth in vitro. Mathematical Medicine and Biology. Online.

PEARSON, T, KING, JR, WATTIS, JAD MACDONALD, I and MAZZATI, D, 2014. A mathematical model of the human metabolic system and metabolic flexibility. Bulletin of Mathematical Biology, 76, 2091-2121.

QI, Q, WATTIS, JAD and BYRNE, HM, 2014. Stochastic simulations of normal aging and Werner's syndrome. Bulletin of Mathematical Biology, 76, 1241-1269.

TIMOFEEVA, Y and COOMBES, S, 2014. Network response of gap junction coupled dendrites, Dendritic computations through morphology and connectivity. In The Computing Dendrite: From Structure to Function, Ed. H Cuntz, M Remme, B Torben-Nielsen, Springer.

WU, X, VAN ZWIETEN, GJ and VAN DER ZEE, KG, 2014. Stabilized second-order convex splitting schemes for Cahn–Hilliard models with application to diffuse-interface tumor-growth models. International Journal for Numerical Methods in Biomedical Engineering, 30(2), 180-203.

ZACHARIOU, M and THUL, R, 2014. Cannabinoid-mediated short-term plasticity in hippocampus. Journal of Computational Neuroscience, 37, 533-547.



BALL, F, BRITTON, T and SIRL, D,     2013.     A network with tunable clustering, degree correlation and degree distribution, and an epidemic thereon.     Journal of Mathematical Biology.     66(4-5),     979-1019.

BOKES, P, KING, JR, WOOD, ATA and LOOSE, M,     2013.     Transcriptional Bursting Diversifies the Behaviour of a Toggle Switch: Hybrid Simulation of Stochastic Gene Expression.     Bulletin of Mathematical Biology, 75,     351-371. 

BRESSLOFF, PC and COOMBES, S,     2013.     Neural ‘Bubble’ Dynamics Revisited.     Cognitive Computation,     5(3),   281-294.

BROOK, BS and JENSEN, OE,    2013.    The role of contractile unit reorganisation in force generation in airway smooth muscle   Mathematical Medicine and Biology, (online).

CABALLERO GAUDES, C, PETRIDOU, N, FRANCIS, ST, DRYDEN, IL and GOWLAND, PA,    2013.    Paradigm free mapping with sparse regression automatically detects single-trial functional magnetic resonance imaging blood oxygenation level dependent responses.    Human Brain Mapping,    34(3),    501-18.

CHAVES, M, FARCOT, E and GOUZÉ, JL,    2013.    Probabilistic approach for predicting periodic orbits in piecewise affine differential models   Bulletin of Mathematical Biology,    75(6),    967-987.

COOMBES, S and TIMOFEEVA, Y,    2013.    Editorial for special issue on Neurodynamics.    Journal of Mathematical Neuroscience,    3(1),    10.

CROISIER, H, TAN, X, PEREZ-ZOGHBI, JF, SANDERSON, MJ, SNEYD, J and BROOK, BS,    2013.    Activation of Store-Operated Calcium Entry in Airway Smooth Muscle Cells: Insight from a Mathematical Model   PLoS One,    8(7),  e69598.

FARCOT, E and YUAN, Y,    2013.    Homogeneous auxin steady states and spontaneous oscillations in flux-based auxin transport models   SIAM Journal on Applied Dynamical Systems,    12(3),    1330-1353.

FIGUEREDO, GP, JOSHI, TV, OSBORNE, JM, BYRNE, HM and OWEN, MR, 2013. On-lattice agent-based simulation of populations of cells within the open-source Chaste framework. Interface Focus, 3(2), 2012.0081

FOZARD JA, KING JR and BENNETT MJ,     2013.     Modelling auxin efflux carrier phosphorylation and localization. Journal of Theoretical Biology,     319,     34-49.

FOZARD, JA, LUCAS, M, KING, JR and JENSEN, OE,    2013.     Vertex-element models for anisotropic growth of elongated plant organs.     Frontiers in Plant Science,     4,     233.

GUÉDON, Y, REFAHI, Y, BESNARD, F, FARCOT, E, GODIN, C and VERNOUX, T,    2013.    Pattern identification and characterization reveal permutations of organs as a key genetically controlled property of post-meristematic phyllotaxis   Journal of Theoretical Biology,   (In Press).

HIRT, BV, WATTIS, JAD and PRESTON, SP, 2013. Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs. Journal of Mathematical Biology, (online).

JABBARI S, STEINER E, HEAP JT, WINZER K, MINTON NP and KING JR,     2013.     The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum.     Mathematical Biosciences,     243,     223-239.

KOUROUNIOTI, RLA, BAND, LR, FOZARD, JA, HAMPSTEAD, A, LOVRIC    S, A, MOYROUD, E, VIGNOLINI, S, KING, JR, JENSEN, OE and GLOVER, BJ,     2013.     Buckling as an origin of ordered cuticular patterns in flower petals. Journal of the Royal Society Interface,     10(80).

LEMON, G and KING, JR,     2013.     Functional Differential Equation Models for Biological Cell Sorting due to Differential Adhesion.     Mathematical Models & Methods in Applied Sciences,     23(1).

LIN KK, WEDGWOOD KCA, COOMBES S and YOUNG L,     2013.     Limitations of perturbative techniques in the analysis of rhythms and oscillations.     Journal of Mathematical Biology,     66,     139-161.

MILLAT, T, JANSSEN, H, THORN, GJ, KING, JR, BAHL, H, FISCHER, R and WOLKENHAUER, O,     2013.     A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicumin phosphate-limited continuous cultures     Applied Microbiology and Biotechnology,    97(14),     6451-6466.

MURARO, D, BYRNE, HM, KING, JR and BENNETT, MJ,     2013.     The role of auxin and cytokinin signalling in specifying the root architecture of Arabidopsis thaliana,     Journal of Theoretical Biology,     317,     71-86.

MURARO, D, VOSS, U, WILSON, M, BENNETT, MJ, BYRNE, HM, DE SMET, I, HODGMAN, C and KING, JR,     2013.  Inference of the Genetic Network Regulating Lateral Root Initiation in Arabidopsis thalia   IEEE-ACM Transactions on Computational Biology and Bioinformatics,    10(1),    50-60.

NELSON, MR, KING, JR and JENSEN, OE, 2013. Buckling of a growing tissue and the emergence of two-dimensional patterns. Mathematical Biosciences, 246(2), 229-241. 

O'DEA, RD, BYRNE, HM and WATERS, SL,    2013.    Continuum modelling of in vitro tissue engineering: a review  In:  L GERIS, ed.,    Computational Modeling in Tissue Engineering    10,    Springer Berlin Heidelberg,    229-266.

O'DEA RD, CROFTS JJ and KAISER M,    2013.    Spreading dynamics on spatially constrained complex brain networks.  Journal of the Royal Society Interface,    10(81),    20130016.

O'DEA, RD and KING, JR,     2013.    The isolation of spatial patterning modes in a mathematical model of juxtacrine cell signalling   Mathematical Medicine and Biology - A Journal of the IMA,    30(2),    95.

OLIVA, M, FARCOT, E and VERNOUX, T,    2013.    Plant hormone signaling during development: insights from computational models   Current Opinion in Plant Biology,    16(1),    19-24.

PÉRET, B,   MIDDLETON AM, FRENCH AP, LARRIEU, A, BISHOPP, A, NJO, M, WELLS, D, PORCO, S, MELLOR, N, BAND, L, CASIMIRO, I, KLEINE-VEHN, J, VANNESTE, S, SAIRANEN, I, MALLET, R, SANDBERG, G, LJUNG, K, BEECKMAN, T, BENKOVA, E, FRIML, J, KRAMER, E, KING, JR, DE SMET, I, PRIDMORE, T, OWEN, MR and BENNETT, MJ, 2013. Sequential induction of auxin efflux and influx carriers regulates lateral root emergence. Molecular Systems Biology, 9, 699.

PICKERING, A, GORDOA, PR and WATTIS, JAD,    2013.    Behaviour of the extended Volterra lattice   Communications in Nonlinear Science and Numerical Simulation, 19(3), 589-600.

SOLDATOS, KP, 2013.  Modelling framework for mass-growth . Mechanics Research Communications, 50, 50-57.

TAXIDIS, J, MIZUSEKI, K, MASON, R and OWEN, MR, 2013. Influence on slow oscillation of hippocampal activity and ripples through cortico-hippocampal synaptic interactions, analyzed by a cortical-CA3-CA1 network mode. Frontiers in Computational Neuroscience, 7, 3.

THORN, GJ, KING, JR and JABBARI, S,     2013.     pH-induced gene regulation of solvent production by Clostridium acetobutylicum in continuous culture: Parameter estimation and sporulation modelling     Mathematical Biosciences,  241(2),     149-166.

TIMOFEEVA Y, COOMBES S and MICHIELETTO D,     2013.     Gap junctions, dendrites and resonances: a recipe for tuning network dynamics.     Journal of Mathematical Neuroscience,     3(1),     15    (In Press.)

VAN BOVEN, M, RUIJS, WL, WALLINGA, J, O'NEILL, PD and HAHNE, S,    2013.    Estimation of mumps vaccine efficacy and critical vaccination coverage   Public Library of Science Computational Biology,    9(5).

WALKER, ML, FARCOT, E, TRAAS, J and GODIN, C,    2013.    The Flux-Based PIN Allocation Mechanism Can Generate Either Canalyzed or Diffuse Distribution Patterns Depending on Geometry and Boundary Conditions    PLoS ONE,    8(1),  e54802.

WEDGWOOD, KC, LIN, KK, THUL, RS and COOMBES, S, 2013. Phase-amplitude descriptions of neural oscillator models. Journal of Mathematical Neuroscience, 3(2).

WILKINSON, RD, 2013. Approximate Bayesian computation (ABC) gives exact results under the assumption of model error. Statistical Applications in Genetics and Molecular Biology, 12(2), 129-141.

WORBY CJ, JEYARATNAM D, ROBOTHAM JV, KYPRAIOS T, O'NEILL PD, DE ANGELIS D, FRENCH G and COOPER BS,  2013.    Estimating the effectiveness of isolation and decolonization measures in reducing transmission of methicillin-resistant Staphylococcus aureus in hospital general wards.    American Journal of Epidemiology,    177(11),    1306-13.

ZACHARIOU, M, ALEXANDER, SPH, COOMBES, S and CHRISTODOULOU, C,     2013.     A biophysical model of endocannabinoid-mediated short term depression in hippocampal inhibition.     PLoS One,     8(3),     e58926.

ZHU, H and OWEN, MR.,     2013.     Damped propagation of cell polarization explains distinct PCP phenotypes of epithelial patterning     Scientific Reports,     3, 2528.



ANBALAGAN, C, LAFAYETTE, I, ANTONIOU-KOUROUNIOTI, M, HAQUE, M, KING, JR, JOHNSEN, B, BAILLIE, D, GUTIERREZ, C, MARTIN, JAR and DE POMERAI, D, 2012. Transgenic nematodes as biosensors for metal stress in soil pore water samples. Ecotoxicology, 21(2), 439-455.

BAKER M, DENMAN-JOHNSON S, BROOK BS, GAYWOOD I and OWEN MR, 2012.Mathematical modelling of cytokine-mediated inflammation in rheumatoid arthritis.  Mathematical Medicine and Biology: A Journal of the IMA, (online).

BAND, L.R, UBEDA-TOMAS, S, DYSON, R.J, MIDDLETON, A.M, HODGMAN, T.C, OWEN, M.R, JENSEN, O.E, BENNETT, M.J and KING, J.R, 2012. Growth-induced hormone dilution can explain the dynamics of plant root cell elongation.   Proceedings Of The National Academy Of Sciences Of The United States Of America, 109(19), 7577-7582.

BAND LR, WELLS DM, LARRIEU A, SUN J, MIDDLETON AM, FRENCH AP, BRUNOUD G, SATO EM, WILSON MH, PÉRET B, OLIVA M, SWARUP R, SAIRANEN I, PARRY G, LJUNG K, BEECKMAN T, GARIBALDI JM, ESTELLE M, OWEN MR, VISSENBERG K, HODGMAN TC, PRIDMORE TP, KING JR, VERNOUX T and BENNETT MJ, 2012. Root Gravitropism Is Regulated By A Transient Lateral Auxin Gradient Controlled By A Tipping-Point Mechanism. Proceedings Of The National Academy Of Sciences Of The United States Of America, 109(12), 4668-4673.

BOOTMAN, MD and THUL, R, 2012. Calcium: Local and Global Cell Messenger. In UVERSKY, VN, KRETSINGER, RH and PERMYAKOV, EA (eds.) Encyclopedia of Metalloproteins (to appear).

BRIDGE, LJ, MIRAMS, GR, KIEFFER, ML, KING, JR and KEPINKSI, S, 2012. Distinguishing possible mechanisms for auxin-mediated developmental control in Arabidopsis: Models with two Aux/IAA and ARF proteins, and two target gene-sets. Mathematical Biosciences, 235(1), 32-44.

COOMBES, S, SCHMIDT, H and BOJAK, I, 2012. Interface dynamics in planar neural field models. Journal of Mathematical Neuroscience, 2(9).

COOMBES, S, THUL, R, LAUDANSKI, J, PALMER, A.R. and SUMNER, C.J., 2012. Neuronal spike-train responses in the presence of threshold noise. Frontiers in Life Sciences, 5(3-4), 91-105.

HIRT, BV, WATTIS, JAD, PRESTON, SP and LAUGHTON, CA, 2012. The effects of a telomere destabilizing agent on cancer cell-cycle dynamics-Integrated modelling and experiments. Journal of Theoretical Biology,295, 9-22.

HOYLE, RB, AVITABILE, D and KIERZEK, AM, 2012. Equation-free analysis of two-component system signalling model reveals the emergence of co-existing phenotypes in the absence of multistationarity. PLoS Computational Biology 8(6): e1002396. 

JABBARI, S, KING, JR and WILLIAMS, P, 2012. Cross-strain quorum sensing inhibition by staphylococcus aureus - Part 1: a spatially homogeneous model. Bulletin of Mathematical Biology, 74, 1292-1325.

JABBARI, S, KING, JR and WILLIAMS, P, 2012. Cross-strain quorum sensing inhibition by staphylococcus aureus - Part 2: a spatially inhomogeneous model. Bulletin of Mathematical Biology, 74, 1326-1353.

MIDDLETON AM, FARCOT E, OWEN MR and VERNOUX T, 2012. Modeling regulatory networks to understand plant development: small is beautiful.  The Plant Cell, 24, 3876-3891.

MIDDLETON AM, UBEDA-TOMÁS S, GRIFFITHS J, HOLMAN T, HEDDEN P, THOMAS SG, PHILLIPS AL, HOLDSWORTH MJ, BENNETT MJ, KING JR and OWEN MR, 2012. Mathematical modeling elucidates the role of transcriptional feedback in gibberellin signaling. Proceedings Of The National Academy Of Sciences Of The United States Of America, 109(19), 7571-7576.

MILLER, CE, BATRA, R, COOPER, BS, PATEL, AK, KLEIN, J, OTTER, JA, KYPRAIOS, T, FRENCH, GL, TOSAS, O and EDGEWORTH, JD, 2012. An Association Between Bacterial Genotype Combined With a High-Vancomycin Minimum Inhibitory Concentration and Risk of Endocarditis in Methicillin-Resistant Staphylococcus aureus Bloodstream Infection. Clinical Infectious Diseases, 54(5), 591-600.

NELSON, MR, BAND, LR, DYSON, RJ, LESSINES, T, WELLS, DM, YANG, C, EVERITT, NM, JENSEN, OE and WILSON, ZA, 2012. A biomechanical model of anther opening reveals the roles of dehydration and secondary thickening. New Phytologist 196(4), 1030-1037.

O'DEA, R and KING, JR, 2012. Continuum limits of pattern formation in hexagonal-cell monolayers. Journal of Mathematical Biology, 64(3), 579-610.

PELLIS, L, BALL, F and TRAPMAN, P, 2012. Reproduction numbers for epidemic models with households and other social structures. I. Definition and calculation of R-0. Mathematical Biosciences, 235(1), 85-97.

SCHENDEL, T, THUL, R, SNEYD, J and FALCKE, M, 2012. How does the ryanodine receptor in the ventricular myocyte wake up: by a single or by multiple open L-type Ca(2+) channels? European Biophysics Journal with Biophysics Letters, 41(1), 27-39.

SVENSSON, CM, COOMBES, S and PIERCE, JW, 2012. Using evolutionary algorithms for fitting high-dimensional models to neuronal data. Neuroinformatics, 10, 199-218.

TAXIDIS, S, Coombes, S, MASON, R and OWEN, MR, 2012. Modeling sharp wave-ripple complexes through a CA3-CA1 network model with chemical synapses. Hippocampus, 22, 995–1017.

THUL, R, 2012. Translating intracellular calcium signalling into models. Cold Spring Harbor Protocols (to appear).

THUL, R, COOMBES, S and BOOTMAN, MD. Persistence of pro-arrhythmic spatio-temporal calcium patterns in atrial myocytes: a computational study of ping waves. Frontiers in Computational Physiology and Medicine, 3, 279.

THUL, R, COOMBES, S, RODERICK, HL and BOOTMAN, MD, 2012. Subcellular calcium dynamics in a whole-cell model of an atrial myocyte. Proceedings of the National Academy of Sciences USA, 109(6), 2150-2155.



ALLEN, E, MOING, A, WATTIS, JAD, LARSON, T, MAUCOURT, M, GRAHAM, IA, ROLIN, D, HOOKS, MA, 2011. Evidence that ACN1 (acetate non-utilizing 1) prevents carbon leakage from peroxisomes during lipid mobilization in Arabidopsis seedlings. Biochemical Journal, 437, 505-513.

BALL, F, BRITTON, T and SIRL, D, 2011. Household epidemic models with varying infection response. Journal of Mathematical Biology, 63(2), 309-337.

BENíTEZ, M, MONK, N. A. M. AND ALVAREZ-BUYLLA, E. R., 2011. Epidermal patterning in Arabidopsis: Models make a difference. Journal of Experimental Zoology B: Molecular and Developmental Evolution, 316B(4), 241-253.

BOOTMAN, MARTIN D, SMYRNIAS, IOANNIS, THUL, RüDIGER, COOMBES, STEPHEN and RODERICK, H LLEWELYN, 2011. Atrial cardiomyocyte calcium signalling. Biochimica et Biophysica Acta, 1813, 922-934.

BRITTON, T, KYPRAIOS, T AND O'NEILL, P.D, 2011. Inference for epidemics with three levels of mixing: methodology and application to a measles outbreak. Scandinavian Journal of Statistics, 38(3), 578-599.

BROOK, B.S., KOHL, P and KING, J.R., 2011. Towards the virtual physiological human: mathematical and computational case studies (preface). Philosophical Transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 369(1954), 4145-4148.

CHERNYAVSKY, I.L., LEACH, L., DRYDEN, I.L. and JENSEN, O.E., 2011. Transport in the placenta: homogenizing haemodynamics in a disordered medium. Philosophical Transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 369(1954), 4162-4182.

COOMBES, S and LAING, C R, 2011. Pulsating fronts in periodically modulated neural field models. Physical review. E, Statistical, nonlinear, and soft matter physics, 83(1-1), 011912.

DUDUIALA, CI, WATTIS, JAD and LAUGHTON, CA, 2011. Self-organised criticality in base-pair breathing in DNA with a defect. Physica D, 240(16), 1254-1261.

FINK, MARTIN, NIEDERER, STEVEN A, CHERRY, ELIZABETH M, FENTON, FLAVIO H, KOIVUMäKI, JUSSI T, SEEMANN, GUNNAR, THUL, RüDIGER, ZHANG, HENGGUI, SACHSE, FRANK B, BEARD, DAN, CRAMPIN, EDMUND J and SMITH, NP, 2011. Cardiac cell modelling: Observations from the heart of the cardiac physiome project. Progress in biophysics and molecular biology, 104, 2-21.

FOZARD, JA, KIRKHAM, GR, BUTTERY, LDK, KING, JR, JENSEN, OE and BYRNE, HM, 2011. Techniques for analysing pattern formation in populations of stem cells and their progeny. BMC Bioinformatics, 12, 396.

GRAEBER, K, LINKIES, A, WOOD, ATA and LEUBNER-METZGER, M, 2011. A Guideline to Family-Wide Comparative State-of-the-Art Quantitative RT-PCR Analysis Exemplified with a Brassicaceae Cross-Species Seed Germination Case Study. Plant Cell, 23(6), 2045-2063.

HAQUE, M, KING, JR, LOOSE, M and de POMERAI, D, 2011. Modelling of the Metallothionein Gene Network in Caenorhabditis elegans: Mathematical Models, Predictions and Laboratory Experiments. ATLA-alternatives to laboratory animals, 39(1), 81-81.

HAUS, S, JABBARI, S, MILLAT, T, JANSSEN, H, FISCHER, RJ, BAHL, H, KING, JR and WOLKENHAUER, O, 2011. A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture. BMC Systems Biology, 5, 10.

JABBARI, S., HEAP, J. T. and KING, J. R., 2011. Mathematical Modelling of the Sporulation-Initiation Network in Bacillus Subtilis Revealing the Dual Role of the Putative Quorum-Sensing Signal Molecule PhrA. Bulletin of Mathematical Biology, 73(1), 181-211.

KING, J.R., 2011. Mathematical modelling of eukaryotic stress-response networks. ATLA-alternatives to laboratory animals, 39(1), 73-73. 

KUWABARA, A, BACKHAUS, A, MALINOWSKI, R, BAUCH, M, HUNT, L, NAGATA, T, MONK, N, SANGUINETTI, G and FLEMING, A, 2011. A shift towards smaller cell size via manipulation of cell cycle gene expression acts to smoothen aridopsis leaf shape. Plant Physiology, 156(4), 2196-2206.

KYPRAIOS, T, O'NEILL, P.D., JONES, D.E., WARE, J, BATRA, R, EDGEWORTH, J.D. and COOPER, B.S., 2011. Effect of systemic antibiotics and topical chlorhexidine on meticillin-resistant Staphylococcus aureus carriage in intensive care unit patients. Journal of Hopsital Infection, 79(3), 222-226.

LEMON, G., HOWARD, D., ROSE, F. R. A. J. and KING, J. R., 2011. Individual-based modelling of angiogenesis inside three-dimensional porous biomaterials. Biosystems, 103(3), 372-383.

LEMON, G., HOWARD, D., YANG, H., RATCHEV, S.M., SEGAL, J.I., ROSE, F.R.A.J., JENSEN, O.E., WATERS, S.L. and KING, J.R., 2011. Growth of the chorioallantoic membrane into a rapid-prototyped model pore system: experiments and mathematical model. Biomechanics and Modeling in Mechanobiology, 10(4), 539-558.

NELSON, M.R., HOWARD, D., JENSEN, O.E., KING, J.R., ROSE, F.R.A.J. and WATERS, S.L., 2011. Growth-induced buckling of an epithelial layer. Biomechanics and Modeling in Mechanobiology, 10(6), 883-900.

O'DEA, R.D., KING, J.R., 2011. Multiscale analysis of pattern formation via intercellular signalling. Mathematical Biosciences, 231(2), 172-185.

OWEN, MARKUS R, STAMPER, I JOHANNA, MUTHANA, MUNITTA, RICHARDSON, GILES W, DOBSON, JON, LEWIS, CLAIRE E and BYRNE, HELEN M, 2011. Mathematical Modeling Predicts Synergistic Antitumor Effects of Combining a Macrophage-Based, Hypoxia-Targeted Gene Therapy with Chemotherapy. Cancer research, 71(8), 2826-2837.

PERFAHL, H, BYRNE, HM, CHEN, TG, ESTRELLA, V, ALARCON, T, LAPIN, A, GATENBY, RA, GILLIES, RJ, LLOYD, MC, MAINI, PK, REUSS, M and OWEN, MR, 2011.  Multiscale Modelling of Vascular Tumour Growth in 3D: The Roles of Domain Size and Boundary Conditions. PLOS ONE, 6(4), e14790.

SARWARDI, S, HAQUE, M and VENTURINO, E, 2011. Global stability and persistence in LG-Holling type II diseased predator ecosystems. Journal of Biological Physics, 37(1), 91-106.

SPENCER, S.E.F., O'NEILL, P.D., 2011. The probability of containment for multitype branching process models for emerging epidemics. Journal of Applied Probability, 48(1), 173-188.

WATERS, S.L., ALASTRUEY, J., BEARD, D.A., BOVENDEERD, P.H.M., DAVIES, P.F., JAYARAMAN, G., JENSEN, O.E., LEE, J., PARKER, K.H., POPEL, A.S., SECOMB, T.W., SHERWIN, S.J., SHIPLEY, R.J., SIEBES, M, SMITH, NP and VAN DE VOSSE, FN, 2011. Theoretical models for coronary vascular biomechanics: progress and challenges. Progress in Biophysical and Molecular Biology, 104, 49-76.

WILKINSON, RD, STEIPER, ME, SOLIGO, C, MARTIN, RD, YANG, ZH and TAVARE, S, 2011. Dating Primate Divergences through an Integrated Analysis of Palaeontological and Molecular Data. Systematic Biology, 60(1), 16-31.



Centre for Mathematical Medicine and Biology

School of Mathematical Sciences
University of Nottingham
Nottingham, NG7 2RD

telephone: +44 (0) 115 846 7214
fax: +44 (0) 115 951 4951
email: markus.owen@nottingham.ac.uk