HURST JR, BAFADHEL M, BOLTON CE, QUINT JK, SAPEY E and WILKINSON TMA, 2018. COPD exacerbations: transforming outcomes through research. The Lancet. Respiratory medicine.
STEINER MC, LOWE D, BECKFORD K, BLAKEY J, BOLTON CE, ELKIN S, MAN WD, ROBERTS CM, SEWELL L, WALKER P and SINGH SJ, 2017. Socioeconomic deprivation and the outcome of pulmonary rehabilitation in England and Wales. Thorax. 72, 530-537 HAKAMY A, MCKEEVER TM, STEINER MC, ROBERTS CM, SINGH SJ and BOLTON CE, 2017. The use of the practice walk test in pulmonary rehabilitation program: National COPD Audit Pulmonary Rehabilitation Workstream. International journal of chronic obstructive pulmonary disease. 12, 2681-2686 SHINDI R, ALMEHAIRI A, NEGM OH, KALSHEKER N, GALE NS, SHALE DJ, HARRISON TW, BOLTON CE, JOHN M, TODD I, TIGHE PJ and FAIRCLOUGH LC, 2017. Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease. Clinical immunology (Orlando, Fla.).
JACKSON VE, NTALLA I, SAYERS I, MORRIS R, WHINCUP P, CASAS JP, AMUZU A, CHOI M, DALE C, KUMARI M, ENGMANN J, KALSHEKER N, CHAPPELL S, GUETTA-BARANES T, MCKEEVER TM, PALMER CN, TAVENDALE R, HOLLOWAY JW, SAYER AA, DENNISON EM, COOPER C, BAFADHEL M, BARKER B, BRIGHTLING C, BOLTON CE, JOHN ME, PARKER SG, MOFFAT MF, WARDLAW AJ, CONNOLLY MJ, PORTEOUS DJ, SMITH BH, PADMANABHAN S, HOCKING L, STIRRUPS KE, DELOUKAS P, STRACHAN DP, HALL IP, TOBIN MD and WAIN LV, 2016. Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. Thorax. 71(6), 501-9 JOHN M, MCKEEVER T, AL HADDAD M, HALL IP, SAYERS I, COCKCROFT JR and BOLTON CE, 2016. Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease. Chronic respiratory disease. 13(3), 247-55 CANE, J.L., MALLIA-MILLANES, B., FORRESTER, D.L., KNOX, A.J., BOLTON, C.E. and JOHNSON, S.R., 2016. Matrix metalloproteinases-8 and-9 in the Airways, Blood and Urine during Exacerbations of COPD COPD: Journal of Chronic Obstructive Pulmonary Disease. 13(1), 26-34 RABINOVICH RA, MILLER BE, WROBEL K, RANJIT K, WILLIAMS MC, DROST E, EDWARDS LD, LOMAS DA, RENNARD SI, AGUSTÍ A, TAL-SINGER R, VESTBO J, WOUTERS EF, JOHN M, VAN BEEK EJ, MURCHISON JT, BOLTON CE, MACNEE W, HUANG JT and , 2016. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD. The European respiratory journal. 47(5), 1365-73
SENTHOORAN SELVARAJAH, IAN TODD, PATRICK TIGHE, MICHELLE JOHN, CHARLOTTE E. BOLTON, TIM HARRISON and LUCY FAIRCLOUGH, 2016. Multiple circulating cytokines are co-elevated in chronic obstructive pulmonary disease. (In Press.)
BOLTON CE, QUINT JK and DRANSFIELD MT, 2016. Cardiovascular disease in COPD: time to quash a silent killer. The Lancet. Respiratory medicine. 4(9), 687-9 HUANG JT, BOLTON CE, MILLER BE, TAL-SINGER R, RABINOVICH R, PALMER CN, THOMSON NC and MACNEE W, 2016. Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease. The European respiratory journal. 48, 1215-1218 SELVARAJAH S, TODD I, TIGHE PJ, JOHN M, BOLTON CE, HARRISON T and FAIRCLOUGH LC, 2016. Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease. Mediators of inflammation. 2016, 3604842 FORSTER S, SMITH S, DANIEL P, BINNION A, BRIGGS L, EVANS R, RYANNA K, WOLTMANN G, BAJAMMAL O, HODGSON D, SAINI G, SCULLION J, BOLTON CE and LOWREY G, 2016. Optimising prescription and titration of oxygen for adult inpatients using novel silicone wristbands: results of a pilot project at three centres. Clinical medicine (London, England). 16(4), 330-4 MILLER S, HENRY AP, HODGE E, KHEIRALLAH AK, BILLINGTON CK, RIMINGTON TL, BHAKER SK, OBEIDAT M, MELÉN E, MERID SK, SWAN C, GOWLAND C, NELSON CP, STEWART CE, BOLTON CE, KILTY I, MALARSTIG A, PARKER SG, MOFFATT MF, WARDLAW AJ, HALL IP and SAYERS I, 2016. The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro. PloS one. 11(10), e0164041 JOHN ME, COCKCROFT JR, MCKEEVER TM, COWARD WR, SHALE DJ, JOHNSON SR, THORNTON JG, HARRISON TW, KNOX AJ and BOLTON CE, 2015. Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. International journal of chronic obstructive pulmonary disease. 10, 211-21 KRISTENSEN JH, LARSEN L, DASGUPTA B, BRODMERKEL C, CURRAN M, KARSDAL MA, SAND JMB, WILLUMSEN N, KNOX AJ, BOLTON CE, JOHNSON SR, HÄGGLUND P, SVENSSON B and LEEMING DJ, 2015. Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders. Clinical biochemistry. SAND JMB, KNOX AJ, LANGE P, SUN S, KRISTENSEN JH, LEEMING DJ, KARSDAL MA, BOLTON CE and JOHNSON SR, 2015. Accelerated extracellular matrix turnover during exacerbations of COPD. Respiratory research. 16(1), 69 BOLTON CE, BUSH A, HURST JR, KOTECHA S and MCGARVEY L, 2015. Lung consequences in adults born prematurely. Postgraduate medical journal. 91(1082), 712-8 POON CY, WATKINS WJ, EVANS CJ, TSAI-GOODMAN B, BOLTON CE, COCKCROFT JR, WISE RG and KOTECHA S, 2015. Pulmonary arterial response to hypoxia in survivors of chronic lung disease of prematurity. Archives of disease in childhood. Fetal and neonatal edition. 101(4), F309-13 CANE JL, MALLIA-MILLANES B, FORRESTER DL, KNOX AJ, BOLTON CE and JOHNSON SR, 2015. Matrix metalloproteinases -8 and -9 in the Airways, Blood and Urine During Exacerbations of COPD. Copd. 13(1), 26-34 AL HADDAD MA, JOHN M, HUSSAIN S and BOLTON CE, 2015. Role of the Timed Up and Go Test in Patients With Chronic Obstructive Pulmonary Disease. Journal of cardiopulmonary rehabilitation and prevention. 36(1), 49-55 BOLTON CE, BUSH A, HURST JR, KOTECHA S and MCGARVEY L, 2015. Lung consequences in adults born prematurely. Thorax. 70(6), 574-80 GALE NS, ALBARRATI AM, MUNNERY MM, MUNNERY IC, IRFAN M, BOLTON CE, RAMBARAN CN, SINGER RM, COCKCROFT JR and SHALE DJ, 2014. Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE): Protocol and preliminary data. Chronic respiratory disease. 11(4), 199-207 BOLTON CE, GALE NS and COCKCROFT JR, 2014. Exercise and cardiovascular benefit in subjects with COPD: the need for randomised trials. The European respiratory journal. 44(1), 263-4
GREEN CJ, HOLLY JM, BOLTON CE, BAYER A, EBRAHIM S, GALLACHER J and BEN-SHLOMO Y, 2014. Role of IGF-I, IGF-II and IGFBP-3 in lung function of males: the Caerphilly Prospective Study. International journal of molecular epidemiology and genetics. 5(2), 112-9
MOHAN D, GALE NS, MCENIERY CM, BOLTON CE, COCKCROFT JR, MACNEE W, FULD J, LOMAS DA, CALVERLEY PM, SHALE DJ, MILLER BE, WILKINSON IB, TAL-SINGER R, POLKEY MI and , 2014. Evaluating the role of inflammation in chronic airways disease: the ERICA study. Copd. 11(5), 552-9 BOLTON CE, SINGH SJ, WALKER PP and BRITISH THORACIC SOCIETY PULMONARY REHABILITATION GUIDELINE GROUP, 2013. Commentary: the British Thoracic Society guideline on pulmonary rehabilitation in adults. Thorax. 68(9), 887-8 BOLTON CE, BEVAN-SMITH EF, BLAKEY JD, CROWE P, ELKIN SL, GARROD R, GREENING NJ, HESLOP K, HULL JH, MAN WD, MORGAN MD, PROUD D, ROBERTS CM, SEWELL L, SINGH SJ, WALKER PP, WALMSLEY S and BRITISH THORACIC SOCIETY PULMONARY REHABILITATION GUIDELINE DEVELOPMENT GROUP, ON BEHALF OF THE BRITISH THORACIC SOCIETY STANDARDS OF CARE COMMITTEE, 2013. British Thoracic Society guideline on pulmonary rehabilitation in adults: accredited by NICE. Thorax. 68 Suppl 2, ii1-ii30 BOLTON CE and BUSH A, 2013. Coming now to a chest clinic near you. Thorax. 68(8), 707-8 BHATTI ZU, SALEK SS, BOLTON CE, GEORGE L, HALCOX JP, JONES SM, KETCHELL IR, MOORE RH, SABIT R, PIGUET V and FINLAY AY, 2013. The development and validation of the major life changing decision profile (MLCDP). Health and quality of life outcomes. 11(1), 78 BHATTI ZU, FINLAY AY, BOLTON CE, GEORGE L, HALCOX JP, JONES SM, KETCHELL RI, MOORE RH and SALEK MS, 2013. Chronic disease influences over 40 major life-changing decisions (MLCDs): a qualitative study in dermatology and general medicine. Journal of the European Academy of Dermatology and Venereology : JEADV. 28(10), 1344-55 POON CY, EDWARDS JM, EVANS CJ, HARRIS AD, TSAI-GOODMAN B, BOLTON CE, COCKCROFT JR, WISE RG and KOTECHA S, 2013. Assessment of pulmonary artery pulse wave velocity in children: an MRI pilot study. Magnetic resonance imaging. 31(10), 1690-4 HODGSON DB, SAINI G, BOLTON CE and STEINER MC, 2012. Thorax In Focus: Chronic Obstructive Pulmonary Disease. Thorax. 67(2), 171-6 BOLTON, C.E., STOCKS, J., HENNESSY, E., COCKCROFT, J.R., FAWKE, J., LUM, S., MCENIERY, C.M., WILKINSON, I.B. and MARLOW, N., 2012. The EPICure study: association between hemodynamics and lung function at 11 years after extremely preterm birth Journal of Pediatrics. 161(4), 595-601.e2 GALE NS, BOLTON CE, DUCKERS JM, ENRIGHT S, COCKCROFT JR and SHALE DJ, 2012. Systemic comorbidities in bronchiectasis. Chronic respiratory disease. 9(4), 231-8 HULL JH, GARROD R, HO TB, KNIGHT RK, COCKCROFT JR, SHALE DJ and BOLTON CE, 2012. Dynamic vascular changes following intravenous antibiotics in patients with cystic fibrosis. Journal of Cystic Fibrosis. 12(2), 125-129 BOLTON CE, STOCKS J, HENNESSY E, COCKCROFT JR, FAWKE J, LUM S, MCENIERY CM, WILKINSON IB and MARLOW N, 2012. The EPICure study: association between hemodynamics and lung function at 11 years after extremely preterm birth. The Journal of pediatrics. 161(4), 595-601.e2
BOLTON, CHARLOTTE E, SCHUMACHER, WIEBKE, COCKCROFT, JOHN R, TIMPSON, NICHOLAS, DAVEY SMITH, GEORGE, GALLACHER, JOHN, RUMLEY, ANNE, LOWE, GORDON DO, EBRAHIM, SHAH, SHALE, DENNIS and BEN-SHLOMO, YOAV, 2011. The CRP Genotype, Serum Levels and Lung Function in men: The Caerphilly Prospective Study. Clinical Science. 12, 347-355
HULL, JAMES H, ANSLEY, LES, BOLTON, CHARLOTTE E, SHARMAN, JAMES E, KNIGHT, RONALD K, COCKCROFT, JOHN R, SHALE, DENNIS J and GARROD, RACHEL, 2011. The effect of exercise on large artery haemodynamics in cystic fibrosis. Journal of Cystic Fibrosis. 10(2), 121-7 ELWYN, GLYN, HARDISTY, ALEX R, PEIRCE, SUSAN C, MAY, CARL, EVANS, ROBERT, ROBINSON, DOUGLAS K R, BOLTON, CHARLOTTE E, YOUSEF, ZAHEER, CONLEY, EDWARD C, RANA, OMER F, GRAY, W ALEX and PREECE, ALUN D, 2011. Detecting deterioration in patients with chronic disease using telemonitoring: navigating the 'trough of disillusionment' Journal of evaluation in clinical practice.
DUCKERS, JAMES M, EVANS, BRONWEN AJ, FRASER, WILLIAM D, STONE, MICHAEL D, BOLTON, CHARLOTTE E and SHALE, DENNIS J, 2011. Low bone mineral density in men with chronic obstructive pulmonary disease. Respiratory research. 12(1), 101
GALE, NICHOLA S, DUCKERS, JAMES M, ENRIGHT, STEPHANIE, COCKCROFT, JOHN R, SHALE, DENNIS J and BOLTON, CHARLOTTE E, 2011. Does Pulmonary Rehabilitation address Cardiovascular Risk Factors in Patients with COPD? BMC Pulmonary Medicine. 11(1), 20
MCENIERY, CARMEL M, BOLTON, CHARLOTTE E, FAWKE, JOSEPH, HENNESSY, ENID, STOCKS, JANET, WILKINSON, IAN B, COCKCROFT, JOHN R and MARLOW, NEIL, 2011. Cardiovascular consequences of extreme prematurity: the EPICure study. Journal of hypertension. 29(7), 1367-73 HARDISTY AR, PEIRCE SC, PREECE A, BOLTON CE, CONLEY EC, GRAY WA, RANA OF, YOUSEF Z and ELWYN G, 2011. Bridging Two Translation Gaps: A New Informatics Research Agenda For Telemonitoring Of Chronic Disease. International Journal Of Medical Informatics. 80(10), 734-44 SABIT, RAMSEY, BOLTON, CHARLOTTE E, FRASER, ALAN G, EDWARDS, JULIE M, EDWARDS, PETER H, IONESCU, ALINA A, COCKCROFT, JOHN R and SHALE, DENNIS J, 2010. Sub-clinical left and right ventricular dysfunction in patients with COPD. Respiratory Medicine. 104(8), 1171-1178 DUCKERS, JAMES M, SHALE, DENNIS J, STOCKLEY, ROBERT A, GALE, NICHOLA S, EVANS, BRONWEN A J, COCKCROFT, JOHN R and BOLTON, CHARLOTTE E, 2010. Cardiovascular and musculskeletal co-morbidities in patients with alpha 1 antitrypsin deficiency. Respiratory Research. 11, 173 BOLTON, CHARLOTTE E and COCKCROFT, JOHN R, 2010. Lung function and cardiovascular risk: a stiff challenge? American Journal of Hypertension. 23(6), 584 BOLTON, CHARLOTTE E, WATERS, CERITH S, PEIRCE, SUSAN and ELWYN, GLYN, 2010. Insufficient evidence of benefit: a systematic review of home telemonitoring for COPD. Journal of Evaluation in Clinical Practice. E published COULSON, J.M., RUDD, J.H.F., DUCKERS, J.M., REES, J.I.S., SHALE, D.J., BOLTON, C.E. and COCKCROFT, J.R., 2010. Excessive aortic inflammation in chronic obstructive pulmonary disease: an 18F-FDG PET pilot study Journal of Nuclear Medicine. 51(9), 1357-1360 BOLTON, C.E., COCKCROFT, J.R., SABIT, R., MUNNERY, M., MCENIERY, C.M., WILKINSON, I.B., EBRAHIM, S., GALLACHER, J.E., SHALE, D.J. and BEN-SHLOMO, Y., 2009. Lung function in mid-life compared with later life is a stronger predictor of arterial stiffness in men: the Caerphilly Prospective Study International Journal of Epidemiology. 38(3), 867-876 MCENIERY, C.M., MCDONNELL, B.J., SO, A., AITKEN, S., BOLTON, C.E., MUNNERY, M., HICKSON, S.S., YASMIN,, MAKI-PETAJA, K.M., COCKCROFT, J.R., DIXON, A.K. and WILKINSON, I.B., 2009. Aortic calcification is associated with aortic stiffness and isolated systolic hypertension in healthy individuals Hypertension. 53(3), 524-531 HULL, J.H., GARROD, R., HO, T.B., KNIGHT, R.K., COCKCROFT, J.R., SHALE, D.J. and BOLTON, C.E., 2009. Increased augmentation index in patients with cystic fibrosis European Respiratory Journal. 34(6), 1322-1328
BOLTON, C E, STONE, M D, EDWARDS, P H, DUCKERS, J M, EVANS, W D and SHALE, D J, 2009. Circulating matrix metalloproteinase-9 and osteoporosis in patients with chronic obstructive pulmonary disease. Chronic Respiratory Disease. 6(2), 81-7
BOLTON, C E, CANNINGS-JOHN, R, EDWARDS, P H, IONESCU, A A, EVANS, W D, PETTIT, R J, FAULKNER, T A, STONE, M D and SHALE, D J, 2008. What community measurements can be used to predict bone disease in patients with COPD? Respiratory Medicine. 102(5), 651-7 SABIT, RAMSEY, GRIFFITHS, TIMOTHY L, WATKINS, ALAN J, EVANS, WENDY, BOLTON, CHARLOTTE E, SHALE, DENNIS J and LEWIS, KEIR E, 2008. Predictors of poor attendance at an outpatient pulmonary rehabilitation programme. Respiratory Medicine. 102(6), 819-24
BOLTON, C E, EVANS, M, IONESCU, A A, EDWARDS, S M, MORRIS, R H K, DUNSEATH, G, LUZIO, S D, OWENS, D R and SHALE, D J, 2007. Insulin resistance and inflammation - A further systemic complication of COPD. COPD. 4(2), 121-6
SABIT, RAMSEY, BOLTON, CHARLOTTE E, EDWARDS, PETER H, PETTIT, REBECCA J, EVANS, WILLIAM D, MCENIERY, CARMEL M, WILKINSON, IAN B, COCKCROFT, JOHN R and SHALE, DENNIS J, 2007. Arterial stiffness and osteoporosis in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 175(12), 1259-65 BOLTON, CHARLOTTE E, BROEKHUIZEN, ROELINKA, IONESCU, ALINA A, NIXON, LISETTE S, WOUTERS, EMIEL F M, SHALE, DENNIS J and SCHOLS, ANNEMIE M W J, 2007. Cellular protein breakdown and systemic inflammation are unaffected by pulmonary rehabilitation in COPD. Thorax. 62(2), 109-14
BOLTON, C E, 2007. A prescription with the self-management plan - a step too far? Chronic Respiratory Disease. 4(3), 129-30
BOLTON, C E, ANNANDALE, J A and EBDEN, P, 2006. Comparison of an oxygen concentrator and wall oxygen in the assessment of patients undergoing long term oxygen therapy assessment. Chronic Respiratory Disease. 3(1), 49-51
IONESCU, ALINA A, MICKLEBOROUGH, TIMOTHY D, BOLTON, CHARLOTTE E, LINDLEY, MARTIN R, NIXON, LISETTE S, DUNSEATH, GARETH, LUZIO, STEVE, OWENS, DAVID R and SHALE, DENNIS J, 2006. The systemic inflammatory response to exercise in adults with cystic fibrosis. Journal of Cystic Fibrosis. 5(2), 105-12 BOLTON, C E, IONESCU, A A, EDWARDS, P H, FAULKNER, T A, EDWARDS, S M and SHALE, D J, 2005. Attaining a correct diagnosis of COPD in general practice. Respiratory Medicine. 99(4), 493-500
BOLTON, CHARLOTTE E, IONESCU, ALINA A, SHIELS, KATHLEEN M, PETTIT, REBECCA J, EDWARDS, PETER H, STONE, MICHAEL D, NIXON, LISETTE S, EVANS, WILLIAM D, GRIFFITHS, TIMOTHY L and SHALE, DENNIS J, 2004. Associated loss of fat-free mass and bone mineral density in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 170(12), 1286-93
BOLTON, C E, IONESCU, A A, EVANS, W D, PETTIT, R J and SHALE, D J, 2003. Altered tissue distribution in adults with cystic fibrosis. Thorax. 58(10), 885-9