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Christopher Partlett

Assistant Professor of Medical Statistics and Clinical Trials, Faculty of Medicine & Health Sciences

Contact

  • workRoom B04 Nottingham Clinical Trials Unit, Applied Health Research Building
    University Park
    Nottingham
    NG7 2RD
    UK
  • work01158231616

Biography

Chris is Assistant Professor of Medical Statistics and Clinical Trials and has been part of the Nottingham Clinical Trials Unit (NCTU) since 2018. He is primarily responsible for providing statistical leadership as part of large multi-disciplinary groups, collaborating on the design and conduct of a broad range of late phase randomised controlled trials.

Prior to his current position he held a joint post between the NCTU and the Research Design Service East Midlands. He has also held similar posts at the University of Oxford and the University of Birmingham.

Selected Publications

  • IFLAIFEL, MAIS, SPRANGE, KIRSTY, BELL, JENNIFER, COOK, ANDREW, GAMBLE, CARROL, JULIOUS, STEVEN A, JUSZCZAK, EDMUND, LINSELL, LOUISE, MONTGOMERY, ALAN and PARTLETT, CHRISTOPHER, 2023. Developing guidance for a risk-proportionate approach to blinding statisticians within clinical trials: a mixed methods study Trials. 24(1), 1-14
  • IFLAIFEL, MAIS, PARTLETT, CHRISTOPHER, BELL, JENNIFER, COOK, ANDREW, GAMBLE, CARROL, JULIOUS, STEVEN, JUSZCZAK, EDMUND, LINSELL, LOUISE, MONTGOMERY, ALAN and SPRANGE, KIRSTY, 2022. Blinding of study statisticians in clinical trials: a qualitative study in UK clinical trials units TRIALS. 23(1),
  • DORLING, JON, ABBOTT, JANE, BERRINGTON, JANET, BOSIAK, BETH, BOWLER, URSULA, BOYLE, ELAINE, EMBLETON, NICHOLAS, HEWER, OLIVER, JOHNSON, SAMANTHA, JUSZCZAK, EDMUND and OTHERS, 2019. Controlled trial of two incremental milk-feeding rates in preterm infants New England Journal of Medicine. 381(15), 1434-1443
  • KNIGHT, M, CHIOCCHIA, V, PARTLETT, C, RIVERO-ARIAS, O, HUA, X, HINSHAW, K and OTHERS, 2019. on behalf of the ANODE collaborative group*. Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial Lancet. 393, 2395-403
  • SAYAL, K., PARTLETT, C., BHARDWAJ, A., DUBICKA, B., MARSHALL, T., GLEDHILL, J., EWART, C., JAMES, M., LANG, A., SPRANGE, K. and MONTGOMERY, A., 2023. Mental health in clinically referred children and young people before and during the Covid-19 pandemic European Child and Adolescent Psychiatry.
  • HALL, C.L., PARTLETT, C., VALENTINE, A.Z., PEARCEY, S. and SAYAL, K., 2023. Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic. Child Psychiatry and Human Development.
  • IFLAIFEL, MAIS, SPRANGE, KIRSTY, BELL, JENNIFER, COOK, ANDREW, GAMBLE, CARROL, JULIOUS, STEVEN A, JUSZCZAK, EDMUND, LINSELL, LOUISE, MONTGOMERY, ALAN and PARTLETT, CHRISTOPHER, 2023. Developing guidance for a risk-proportionate approach to blinding statisticians within clinical trials: a mixed methods study Trials. 24(1), 1-14
  • TAKWOINGI, YEMISI, DENDUKURI, NANDINI, SCHILLER, IAN, RÜCKER, GERTA, JONES, HAYLEY E, PARTLETT, CHRISTOPHER and MACASKILL, PETRA, 2023. Undertaking meta-analysis Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. 249-325
  • BAKER, ARABELLA, MITCHELL, ELEANOR J, PARTLETT, CHRISTOPHER and THOMAS, KIM S, 2023. Evaluating the effect of weekly patient-reported symptom monitoring on trial outcomes: results of the Eczema Monitoring Online randomised controlled trial British Journal of Dermatology. ljad163
  • CLARKE, PAUL, SOE, AUNG, NICHOLS, AMY, HARIZAJ, HELEN, WEBBER, MARK A, LINSELL, LOUISE, BELL, JENNIFER L, TREMLETT, CATHERINE, MUTHUKUMAR, PRIYADARSINI, PATTNAYAK, SANTOSH and OTHERS, 2023. 2% chlorhexidine gluconate aqueous versus 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to percutaneous central venous catheterisation: the ARCTIC randomised controlled feasibility trial Archives of Disease in Childhood-Fetal and Neonatal Edition.
  • MITCHELL, ELEANOR J., MEAKIN, GARRY, ANDERSON, JOSIE, DORLING, JON, GALE, CHRIS, HAINES, RACHEL, KENYAN, CHARLOTTE, JOHNSON, MARK J., MCGUIRE, WILLIAM, MISTRY, HEMA, MONTGOMERY, ALAN, ODDIE, SAM, OGOLLAH, REUBEN, PALLOTTI, PHOEBE, PARTLETT, CHRISTOPHER, WALKER, KATE F. and OJHA, SHALINI, 2022. The FEED1 trial: protocol for a randomised controlled trial of full milk feeds versus intravenous fluids with gradual feeding for preterm infants (30-33 weeks gestational age) TRIALS. 23(1),
  • IFLAIFEL, MAIS, PARTLETT, CHRISTOPHER, BELL, JENNIFER, COOK, ANDREW, GAMBLE, CARROL, JULIOUS, STEVEN, JUSZCZAK, EDMUND, LINSELL, LOUISE, MONTGOMERY, ALAN and SPRANGE, KIRSTY, 2022. Blinding of study statisticians in clinical trials: a qualitative study in UK clinical trials units TRIALS. 23(1),
  • MITCHELL, ELEANOR J, MEAKIN, GARRY, ANDERSON, JOSIE, DORLING, JON, GALE, CHRIS, HAINES, RACHEL, KENYAN, CHARLOTTE, JOHNSON, MARK J, MCGUIRE, WILLIAM, MISTRY, HEMA and OTHERS, 2022. The FEED1 trial: protocol for a randomised controlled trial of full milk feeds versus intravenous fluids with gradual feeding for preterm infants (30-33 weeks gestational age) Trials. 23(1), 1-12
  • IFLAIFEL, MAIS, PARTLETT, CHRISTOPHER, BELL, JENNIFER, COOK, ANDREW, GAMBLE, CARROL, JULIOUS, STEVEN, JUSZCZAK, EDMUND, LINSELL, LOUISE, MONTGOMERY, ALAN and SPRANGE, KIRSTY, 2022. Blinding of study statisticians in clinical trials: a qualitative study in UK clinical trials units Trials. 23(1), 535
  • SAYAL, KAPIL, PARTLETT, CHRISTOPHER, BHARDWAJ, ANUPAM, DUBICKA, BERNADKA, MARSHALL, TAMSIN, GLEDHILL, JULIA, EWART, COLLEEN, JAMES, MARILYN, LANG, ALEXANDRA, SPRANGE, KIRSTY and OTHERS, 2022. Mental health in clinically referred children and young people before and during the Covid-19 pandemic European Child & Adolescent Psychiatry. 1-10
  • BRUCE, CYDNEY L, JUSZCZAK, EDMUND, OGOLLAH, REUBEN, PARTLETT, CHRISTOPHER and MONTGOMERY, ALAN, 2022. A systematic review of randomisation method use in RCTs and association of trial design characteristics with method selection BMC Medical Research Methodology. 22(1), 314
  • JUSZCZAK, EDMUND, HEWER, OLIVER, PARTLETT, CHRISTOPHER, HURD, MADELEINE, BARI, VASHA, BOWLER, URSULA, LINSELL, LOUISE and DORLING, JON, 2021. Evaluation of the effectiveness of an incentive strategy on the questionnaire response rate in parents of premature babies: a randomised controlled study within a trial (SWAT) nested within SIFT Trials. 22(1), 554
  • GODOLPHIN, PETER J., BATH, PHILIP M., PARTLETT, CHRISTOPHER, BERGE, EIVIND, BROWN, MARTIN M., ELIASZIW, MISHA, SANDSET, PER MORTEN, SERENA, JOAQUIN and MONTGOMERY, ALAN A., 2020. Outcome assessment by central adjudicators in randomised stroke trials: Simulation of differential and non-differential misclassification EUROPEAN STROKE JOURNAL. 5(2), 174-183
  • TAKWOINGI, YEMISI, PARTLETT, CHRISTOPHER, RILEY, RICHARD D, HYDE, CHRIS and DEEKS, JONATHAN J, 2020. Methods and reporting of systematic reviews of comparative accuracy were deficient: a methodological survey and proposed guidance Journal of clinical epidemiology. 121, 1-14
  • PARTLETT, CHRISTOPHER, HALL, NIGEL J, LEAF, ALISON, JUSZCZAK, EDMUND and LINSELL, LOUISE, 2020. Application of the matched nested case-control design to the secondary analysis of trial data BMC medical research methodology. 20, 1-8
  • GODOLPHIN, PETER J, BATH, PHILIP M, PARTLETT, CHRISTOPHER, BERGE, EIVIND, BROWN, MARTIN M, ELIASZIW, MISHA, SANDSET, PER MORTEN, SERENA, JOAQUÍN and MONTGOMERY, ALAN A, 2020. Outcome assessment by central adjudicators in randomised stroke trials: simulation of differential and non-differential misclassification European Stroke Journal. 5(2), 174-183
  • TAHIR, WARDA, MONAHAN, MARK, DORLING, JON, HEWER, OLIVER, BOWLER, URSULA, LINSELL, LOUISE, PARTLETT, CHRISTOPHER, BERRINGTON, JANET ELIZABETH, BOYLE, ELAINE, EMBLETON, NICOLAS and OTHERS, 2020. Economic evaluation alongside the Speed of Increasing milk Feeds Trial (SIFT) Archives of disease in childhood-Fetal and neonatal edition. 105(6), 587-592
  • DORLING, JON, HEWER, OLIVER, HURD, MADELEINE, BARI, VASHA, BOSIAK, BETH, BOWLER, URSULA, KING, ANDREW, LINSELL, LOUISE, MURRAY, DAVID, OMAR, OMAR and OTHERS, 2020. Two speeds of increasing milk feeds for very preterm or very low-birthweight infants: the SIFT RCT. Health Technology Assessment (Winchester, England). 24(18), 1
  • DORLING, JON, HEWER, OLIVER, HURD, MADELEINE, BARI, VASHA, BOSIAK, BETH, BOWLER, URSULA, KING, ANDREW, LINSELL, LOUISE, MURRAY, DAVID, OMAR, OMAR and OTHERS, 2020. Strategies to enhance follow-up return rates. In: Two speeds of increasing milk feeds for very preterm or very low-birthweight infants: the SIFT RCT NIHR Journals Library.
  • DORLING, JON, HEWER, OLIVER, HURD, MADELEINE, BARI, VASHA, BOSIAK, BETH, BOWLER, URSULA, KING, ANDREW, LINSELL, LOUISE, MURRAY, DAVID, OMAR, OMAR and OTHERS, 2020. Economic evaluation. In: Two speeds of increasing milk feeds for very preterm or very low-birthweight infants: the SIFT RCT NIHR Journals Library.
  • DORLING, JON, HEWER, OLIVER, HURD, MADELEINE, BARI, VASHA, BOSIAK, BETH, BOWLER, URSULA, KING, ANDREW, LINSELL, LOUISE, MURRAY, DAVID, OMAR, OMAR and OTHERS, 2020. Parental experiences of being approached to join multiple neonatal clinical trials: a qualitative study,‘PARENT’. In: Two speeds of increasing milk feeds for very preterm or very low-birthweight infants: the SIFT RCT NIHR Journals Library.
  • WHITWORTH HS, BADHAN A, BOAKYE AA, TAKWOINGI Y, REES-ROBERTS M, PARTLETT C, LAMBIE H, INNES J, COOKE G, LIPMAN M, CONLON C, MACALLAN D, CHUA F, POST FA, WISELKA M, WOLTMANN G, DEEKS JJ, KON OM, LALVANI A and , 2019. Clinical utility of existing and second-generation interferon-γ release assays for diagnostic evaluation of tuberculosis: an observational cohort study. The Lancet. Infectious diseases. 19(2), 193-202
  • GRIFFITHS, JAMES, JENKINS, PAULA, VARGOVA, MONIKA, BOWLER, URSULA, JUSZCZAK, EDMUND, KING, ANDREW, LINSELL, LOUISE, MURRAY, DAVID, PARTLETT, CHRISTOPHER, PATEL, MEHALI, BERRINGTON, JANET, EMBLETON, NICHOLAS, DORLING, JON, HEATH, PAUL, ODDIE, SAM, MCGUIRE, WILLIAM, AINSWORTH, SEAN, BARTLE, DAVID, BATRA, DUSHYANT, BOYLE, ELAINE, CLARKE, PAUL, CRAIG, STANLEY, ELLIS, SARAH, GARG, SHALABH, GEETHANATH, RUPPA, GIBSON, DAVID, GOWDA, GIRISH, GUPTA, RICHA, HOLDER, GEMMA, JANAKIRAMAN, SUNDARAM, JOHNSON, KATHRYN, JOHNSON, MARK, KENNEA, NIGEL, KUMAR, YADLAPALLI, LEDWIDGE, MARY, MACTIER, HELEN, MANJUNATHA, C. M., MATTHES, JEAN, OHADIKE, PAMELA, PETERS, COLIN, PILING, ELIZABETH, QUINE, DAVID, REYNOLDS, PETER, ROEHR, CHARLES, SCORRER, TIM, STORY, IMOGEN, VAILCUTZ, RIMA, VASU, VIMAL, YATES, HELEN, COOKE, RICHARD, HUTCHISON, FAN, EWER, ANDREW, HELLIER, JENNIFER, BAUM, ALISON, MANNIX, PAUL, HALLIDAY, HENRY, SUBHEDAR, NIM, MILLAR, MICHAEL and BRADBURN, MIKE, 2019. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial LANCET. 393(10170), 423-433
  • WHITWORTH, HILARY S, BADHAN, AMARJIT, BOAKYE, AIME A, TAKWOINGI, YEMISI, REES-ROBERTS, MELANIE, PARTLETT, CHRISTOPHER, LAMBIE, HEATHER, INNES, JOHN, COOKE, GRAHAM, LIPMAN, MARC and OTHERS, 2019. Clinical utility of existing and second-generation interferon-$gamma$ release assays for diagnostic evaluation of tuberculosis: an observational cohort study The Lancet Infectious Diseases. 19(2), 193-202
  • TAKWOINGI, YEMISI, WHITWORTH, HILARY, REES-ROBERTS, MELANIE, BADHAN, AMARJIT, PARTLETT, CHRISTOPHER, GREEN, NATHAN, BOAKYE, AIME, LAMBIE, HEATHER, MARONGIU, LUIGI, JIT, MARK and OTHERS, 2019. Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation. Health Technology Assessment (Winchester, England). 23(23), 1
  • WHITWORTH, HILARY S, BADHAN, AMARJIT, BOAKYE, AIME A, TAKWOINGI, YEMISI, REES-ROBERTS, MELANIE, PARTLETT, CHRISTOPHER, LAMBIE, HEATHER, INNES, JOHN, COOKE, GRAHAM, LIPMAN, MARC and OTHERS, 2019. An observational cohort study to evaluate the clinical utility of current and second-generation interferon-gamma release-assays in diagnostic evaluation of tuberculosis Lancet Infectious Diseases. 19(2), 193-202
  • KNIGHT, MARIAN, CHIOCCHIA, VIRGINIA, PARTLETT, CHRISTOPHER, RIVERO-ARIAS, OLIVER, HUA, XINYANG, HINSHAW, KIM, TUFFNELL, DEREK, LINSELL, LOUISE, JUSZCZAK, EDMUND, ENDERBY, HELEN and OTHERS, 2019. Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial The Lancet. 393(10189), 2395-2403
  • DORLING, JON, ABBOTT, JANE, BERRINGTON, JANET, BOSIAK, BETH, BOWLER, URSULA, BOYLE, ELAINE, EMBLETON, NICHOLAS, HEWER, OLIVER, JOHNSON, SAMANTHA, JUSZCZAK, EDMUND and OTHERS, 2019. Controlled trial of two incremental milk-feeding rates in preterm infants New England Journal of Medicine. 381(15), 1434-1443
  • KNIGHT, M, CHIOCCHIA, V and PARTLETT, C, 2019. Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial (vol 393, pg 2395, 2019) LANCET. 393(10189), 2394-2394
  • KNIGHT, MARIAN, CHIOCCHIA, VIRGINIA, PARTLETT, CHRISTOPHER, RIVERO-ARIAS, OLIVER, HUA, XINYANG, BOWLER, URSULA, GRAY, JAMES, GRAY, SHAN, HINSHAW, KIM, KHUNDA, AETHELE and OTHERS, 2019. Intravenous co-amoxiclav to prevent infection after operative vaginal delivery: the ANODE RCT. Health Technology Assessment (Winchester, England). 23(54), 1
  • TAKWOINGI, YEMISI, WHITWORTH, HILARY, REES-ROBERTS, MELANIE, BADHAN, AMARJIT, PARTLETT, CHRISTOPHER, GREEN, NATHAN, BOAKYE, AIME, LAMBIE, HEATHER, MARONGIU, LUIGI, JIT, MARK and OTHERS, 2019. Studies of interferon gamma release assays for the diagnosis of active tuberculosis. In: Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation NIHR Journals Library.
  • PARTLETT, CHRISTOPHER, HALL, NIGEL, LEAF, ALISON, JUSZCZAK, ED and LINSELL, LOUISE, 2019. A novel application of the matched nested case-control design in the secondary analysis of clinical trial data In: TRIALS.
  • TAKWOINGI, YEMISI, WHITWORTH, HILARY, REES-ROBERTS, MELANIE, BADHAN, AMARJIT, PARTLETT, CHRISTOPHER, GREEN, NATHAN, BOAKYE, AIME, LAMBIE, HEATHER, MARONGIU, LUIGI, JIT, MARK and OTHERS, 2019. Diagnostic accuracy results. In: Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation NIHR Journals Library.
  • TAKWOINGI, YEMISI, WHITWORTH, HILARY, REES-ROBERTS, MELANIE, BADHAN, AMARJIT, PARTLETT, CHRISTOPHER, GREEN, NATHAN, BOAKYE, AIME, LAMBIE, HEATHER, MARONGIU, LUIGI, JIT, MARK and OTHERS, 2019. Economic evaluation results. In: Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation NIHR Journals Library.
  • TAKWOINGI, YEMISI, WHITWORTH, HILARY, REES-ROBERTS, MELANIE, BADHAN, AMARJIT, PARTLETT, CHRISTOPHER, GREEN, NATHAN, BOAKYE, AIME, LAMBIE, HEATHER, MARONGIU, LUIGI, JIT, MARK and OTHERS, 2019. Substudy of human immunodeficiency virus-positive participants. In: Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation NIHR Journals Library.
  • KNIGHT, M, CHIOCCHIA, V, PARTLETT, C, RIVERO-ARIAS, O, HUA, X, HINSHAW, K and OTHERS, 2019. on behalf of the ANODE collaborative group*. Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial Lancet. 393, 2395-403
  • GRIFFITHS J, JENKINS P, VARGOVA M, BOWLER U, JUSZCZAK E, KING A, LINSELL L, MURRAY D, PARTLETT C, PATEL M, BERRINGTON J, EMBLETON N, DORLING J, HEATH PT, MCGUIRE W and ODDIE S, 2018. Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT. Health technology assessment (Winchester, England). 22(74), 1-60
  • YAMAGUCHI Y, MARUO K, PARTLETT C and RILEY RD, 2017. A random effects meta-analysis model with Box-Cox transformation. BMC medical research methodology. 17(1), 109
  • PARTLETT, CHRISTOPHER, LINSELL, LOUISE, HEWER, P, JUSZCZAK, ED and DORLING, JON, 2017. The impact of blinded endpoint review on the incidence of primary short-term outcomes in the SIFT trial TRIALS. 18(Suppl 1),
  • PARTLETT, C and TAKWOINGI, Y, 2016. Meta analysis of test accuracy studies in R: a summary of user-written programs and step-by-step guide to using glmer. Version 1.0 august 2016 Available at methods. cochrane. org/sdt/.
  • PARTLETT, C and TAKWOINGI, Y, 2016. Meta-analysis of test accuracy studies in R: a summary of userwritten programs and step-by-step guide to using glmer Version 1.0.

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