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Kate Walker

Clinical Associate Professor In Obstetrics, Faculty of Medicine & Health Sciences

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Biography

I am currently a Clinical Associate Professor in Obstetrics, at the University of Nottingham. I work full time and divide my time equally between research and clinical work. My research work is based in Nottingham Clinical Trials Unit (NCTU). My clinical work is based at Queen's Medical Centre, Nottingham University Hospitals Trust.

Clinically I have an interest in high risk pregnancy, labour ward management and obstetric ultrasound scanning.

My research work has focused on randomised controlled trials in obstetrics and neonatology.

For my PhD I conducted a randomised controlled trial of induction of labour at 39 weeks versus expectant management for women over 35 years of age - the "35/39 trial", I was co-applicant on the £250K Research for Patient Benefit grant and I was the first author of the paper which was published in the NEJM in 2016.

I am the Clinical Chief Investigator for an NIHR HTA funded cluster randomised trial with economic and acceptability evaluations to determine the clinical and cost-effectiveness of testing for Group B Streptococcus in late pregnancy (GBS3). This is the first RCT of routine GBS screening in the world.

I am the Chief Investigator of an NIHR HTA funded study to determine the feasibility of a randomised trial of different techniques for managing an impacted fetal head during emergency caesarean section. This study started in February 2019.

Expertise Summary

Randomised controlled trials. General obstetrics. General gynaecology. Qualitative research. Health economics.

Teaching Summary

TRAINING TO TEACH

In 2019 I received a Postgraduate certificate in Higher Education (15 credits) following completion of an 'Individual Pathway' module. This involved completing 3 days of workshops on learning/teaching topics, and then I completed a teaching development and submitted a written report for assessment. The workshops I attended were:

  • Foundations of teaching in Higher Education
  • Contemporary issues in supervising research students
  • Assessing & giving feedback
  • Introduction to Learning Technologies
  • Internet Based Collaboration Tools

PRACTICE

I have always had a great passion for teaching and have regularly taught medical students and junior trainees through seminars, lectures and small group tutorials throughout my training. In my current post my teaching has involved:

  • Main supervisor for a BMedSci student who undertook a project involving a regional audit of laparoscopic hysterectomies in the East Midlands
  • Supervision of an UoN Assisted Reproduction Masters student
  • Supervision of a UoN PhD student, undertaking a PhD on the assessment of endometrial receptivity in response to progesterone exposure and endometrial biopsy: progesterone, endometrial gene expression, and endometrial vascularity
  • Undergraduate lecture to third year medical students on 'Antenatal Care in Healthy Singletons' in Dec 2018
  • Participation in the Medical Students interviews (Dec 2017 and 2018)
  • Delivered lectures on the Part 2 MRCOG Revision Course, University of Nottingham - Jun 2017, Nov 2017
  • Examiner for BMedSci Dissertation and Viva - Feb 2014, Feb 2018, Feb 2019
  • Supervised a second year Foundation Doctor (FY2), Dr Philippa Wilson, during a four month academic post in 2014
  • Facilitator on the Inter-professional Study Day for fourth year medical students and third year student midwives where lead a session on labour ward prioritization.

WEB-BASED LEARNING PACKAGES

StratOG (RCOG's online learning resource)

Revised and updated eLearning tutorials on Postpartum sepsis (2013) and Infectious Diseases (2013)

AWARDS

In 2019 I was nominated for a Nottingham University Hospitals NHS Trust Postgraduate Medical Education Department award for my Contribution to Undergraduate Teaching 18-19.

Research Summary

I am the Chief Investigator of an NIHR HTA funded study to determine the feasibility of a randomised trial of different techniques for managing an impacted fetal head during emergency caesarean… read more

Recent Publications

Current Research

I am the Chief Investigator of an NIHR HTA funded study to determine the feasibility of a randomised trial of different techniques for managing an impacted fetal head during emergency caesarean section. This study started in February 2019 and will take 24 months to complete.

I am the Clinical Chief Investigator of an NIHR HTA funded cluster randomised trial with economic and acceptability evaluations to determine the clinical and cost-effectiveness of testing for Group B Streptococcus in late pregnancy (GBS3). This study started in April 2019 and will take 36 months to complete.

Past Research

Peer reviewed original research

Kate F Walker, Keelin O'Donoghue, Nicky Grace, Jon Dorling, Jeannette L Comeau, Wentao Li, Jim G Thornton. Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: A systematic review and critical analysis. British Journal of Obstetrics and Gynaecology 2020

Charlotte Hickson, Felicity Hoskins, Reuben Ogollah, Kate F Walker, Jim G Thornton. The risks of a range of maternal pregnancy choices, expressed as "baby micromorts" (risk of death per million births). European Journal of Obstetrics and Gynecology and Reproductive Biology 2020; https://doi.org/10.1016/j.ejogrb.2020.05.051

Rebecca Robinson, Kate F Walker, Victoria A White, George J Bugg, Kym IE Snell, Nia W Jones. The test accuracy of antenatal ultrasound definitions of fetal macrosomia to predict birth injury: a systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology 2020; 246: 79-85

Sutham Suthaporn, Kanna Jayaprakasan, Walid Maalouf, James G. Thornton, Kate F. Walker. The strength of evidence supporting luteal phase progestogen after assisted reproduction: a systematic review with reference to trial registration and pre-specified endpoints. European Journal of Obstetrics and Gynecology and Reproductive Biology 2020; 245: 149-161

Kate F Walker, Anna Dencker, Jim G Thornton. Childbirth Experience Questionnaire 2: Validating its Use in the United Kingdom. European Journal of Obstetrics and Gynecology and Reproductive Biology 2020; 5: 100097 http://dx.doi.org/10.1016/j.eurox.2019.100097

Victoria White, Kate F Walker and Jim G Thornton. Trials of antenatal corticosteroids for preterm fetal lung maturity: a review of the potential for selective outcome reporting. European Journal of Obstetrics and Gynecology and Reproductive Biology 2019

Diane Whitham. Julie Turzanski, Lucy Bradshaw, Mike Clarke, Lucy Culliford, Lelia Duley, Lisa Shaw, Zoe Skea, Shaun P.Treweek, Kate F Walker, Paula R. Williamson, Alan Montgomery. Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study. Trials 2018; 19: 557

Kate F Walker; Julie Turzanski; Diane Whitham; Alan Montgomery; Lelia Duley. Monitoring performance of sites within multicentre randomised trials: A systematic review of performance metrics. Trials 2018; 19: 562.

Kate Bramham, Lucy Chappell, Kate F Walker, Lesia Kurlak, Amanda Green, Pamela Loughna, Daniele Cristovao Escouto. Postpartum Evaluation of Cardiovascular Disease Risk for Women with Pregnancies Complicated by Hypertension. Pregnancy Hypertension 2018; 13: 218-224

Kate F Walker, Melina Dritsaki, George J Bugg, Marion Macpherson, Carol McCormick, Nicky Grace, Chris Wildsmith Lucy Bradshaw, Gordon C S Smith, James G Thornton. Labour induction near term for women aged 35 or over; an economic evaluation of a randomised trial. BJOG 2017: 124 (6)

Kate F Walker, George J Bugg, Marion Macpherson, Carol McCormick, Nicky Grace, Chris Wildsmith Lucy Bradshaw, Gordon C S Smith, James G Thornton. A randomized controlled trial of labor induction for women aged 35 or over. NEJM 2016; 374:813-22.

Kate F Walker, Lucy Bradshaw, George J Bugg and Jim G Thornton. Causes of antepartum stillbirth in women of advanced maternal age. European Journal of Obstetrics and Gynecology and Reproductive Biology 197 (2016) 86-90.

Kate F Walker, Gemma Malin, Philippa Wilson and Jim G Thornton. Induction of labour versus expectant management at term by subgroups of maternal age: an individual patient data meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology 197 (2016) 1-5.

Kate F Walker, Philippa Wilson, George J Bugg, Anna Dencker and Jim G Thornton. Childbirth experience questionnaire: validating its use in the United Kingdom. BMC Pregnancy and Childbirth (2015) 15:86.

Kate F Walker, Graham Stevenson and James Thornton. Still discrepancies between registration and publication of randomised controlled trials: an observational study. Journal of the Royal Society of Medicine Short Reports 2014: 5(5) 1-4.

Kate Walker, Abigail Cohen, Sophie Walker, Kirsten Allen, Darrin Baines, Jim Thornton. Dangers of the day of birth: an observational study. BJOG 2014; 121:714-718.

Kate F Walker, George J Bugg, Marion Macpherson, Carol McCormick James Thornton. Induction of labour versus expectant management for nulliparous women over 35 years of age: a multi-centre prospective, randomised controlled trial. BMC Pregnancy and Childbirth 2012, 12:145.

Kate F Walker, George J Bugg, Marion Macpherson, James Thornton. Induction of labour at term for women over 35 years old: a survey of the views of women and obstetricians. European Journal of Obstetrics and Gynecology and Reproductive Biology 2012 162(2):144-8

Zeina J Haoula, Kate F Walker, Martin C Powell. Levonorgestrel intra-uterine system as a treatment option for complex endometrial hyperplasia. European Journal of Obstetrics and Gynecology and Reproductive Biology 2011; 159 (1):176-179.

Kate Frances Walker, Honor Day, Jafaru Abu, David Nunns, Karin Williamson, Tim Duncan. Do surgical techniques used in groin lymphadenectomy for vulval cancer affect morbidity rates? International Journal of Gynecological Cancer 2011; 21(8):1495-1499.

K. Jayaprakasan, K.F. Walker, J.S. Clewes, I.R. Johnson & N.J. Raine-Fenning. The interobserver reliability of off-line antral follicle counts made from stored three-dimensional ultrasound data; a comparative study of different measurement techniques. Ultrasound in Obstetrics and Gynecology 2007; 29: 335-341.

Ala'Aldeen, D.A.A., Robinson, K., Wooldridge, K.G., Bland, S.J., Wells, D.B., Riordan (Walker), K.F., Taraktsoglou, M. & Todd, I. The meningococcal TspA protein is vital for normal type IV pilus biogenesis and function. Abstracts of the Thirteenth International Pathogenic Neisseria Conference. Norway 2002

Invited commentaries

Kate F Walker and James G Thornton. Encouraging maternal reporting of altered fetal movements in pregnancy is ineffective and harmful. The Lancet. Accepted for publication 23rd July 2018

Kate F Walker and James G Thornton. Induction of labour at 37 weeks for suspected fetal macrosomia may reduce birth trauma. Evidence-Based Medicine. Published online 23rd June 2017. Doi: 10.1136/ebmed-2017-110693

Kate F Walker and James G Thornton. Tocolysis and preterm labour. The Lancet (2016). Published online 1st March 2016.

Invited reviews

Kate F. Walker, G.J. Bugg. Is it time to ban oxytocin for poor labour progress? Obstetrics, Gynaecology and Reproductive Medicine 2019.

Walker KF, Kibuka M, Thornton JG, Jones NW. Maternal position in the second stage of labour for women with epidural anaesthesia. Cochrane Database of Systematic Reviews 2018 Issue 11.

K.F. Walker, C. Gribbin, F. Siddiqui. Cultural aspects of care in obstetrics and gynaecology. Obstetrics, Gynaecology and Reproductive Medicine 2018; 28.

Churchill D, Duley L, Thornton JG, Moussa M, Ali HSM, Walker KF. Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation. Cochrane Database of Systematic Reviews 2018 Issue 10. Art. No.: CD003106

K.F. Walker, J Thornton. Delivery at term: when, how and why. Clinics in Perinatology 2018; 45: 2, p 199-211.

K.F. Walker, J Thornton. Advanced maternal age. Obstetrics, Gynaecology and Reproductive Medicine 2016; 26.

K.F. Walker, K. Jayaprakasan, N.J. Raine-Fenning. Ultrasound in benign gynaecology. Obstetrics, Gynaecology and Reproductive Medicine 2007; 17:2.

Case reports

Philippa Wilson, Kate F Walker, Clare Gribbin and James G Thornton. A case of aortic dissection diagnosed postnatally. European Journal of Obstetrics and Gynecology and Reproductive Biology 183 (2014) 205.

Kate F. Walker, Jaydip Dasgupta and Michael P. Cust. A neglected shelf pessary resulting in an urethrovaginal fistula. International Urogynecology Journal 2011; 22(10):1333-1334.

Letters

K Walker and J Thornton Dangers of the day of birth: an observational study (Author's comment). BJOG 2014; 121 (10), pages 1320-1321.

Book Chapters

Chapter on 'Ethics in Medicine' in Medicolegal Issues in Obstetrics and Gynaecology. In Press.

Chapter on 'Prolonged Pregnancy' in Oxford University Press Textbook of Obstetrics and Gynaecology. In Press.

StratOG (RCOG's online learning resource)

Revised and updated eLearning tutorials on Postpartum sepsis (2013) and Infectious Diseases (2013)

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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