School of Medicine
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Kirsty Sprange

Assistant Professor of Clinical Trials, Faculty of Medicine & Health Sciences



Kirsty is Assistant Professor of Clinical Trials at the University of Nottingham Clinical Trials Unit (NCTU) She has over 15 years' experience working in research including design and delivery of randomised controlled trials, feasibility and pilot studies as well as qualitative methodology including interviews, focus groups, fidelity assessment and process evaluation. She has worked in the unit since 2014 in a range of roles including Trial Manager, Senior Trial Manager and now her current Assistant Professor post. Prior to joining the NCTU she worked for the Sheffield Clinical Trials Research Unit (CTRU) in the School of Health and Related Research (ScHARR) as a Research Associate. Prior to that she worked for the Healthcare Innovation and Technology Evaluation Centre (HITEC) based at Derby Hospitals NHS Foundation Trust where she carried out systematic reviews, evidence reviews and technical evaluations of assistive technologies and medical devices for a number of commissioners. These included the Centre for Evidence-based Purchasing (CEP) part of the Purchasing and Supply Chain (PASA) and the National Institute for Health and Clinical Excellence (NICE).

Her main research interest is in adult and child mental health in which she is co-applicant on several large multi-centre NIHR HTA funded trials in the UK. She has a specific interest in older adults and dementia particularly occupational therapy based interventions exploring self-management for maintaining independent living as well as mental and physical wellbeing. She also has a strong interest in fidelity assessment of complex intervention and qualitative research.

Teaching Summary

She is a lead for the Fundamentals of Clinical Trials course aimed at teaching the basics of clinical trial design and conduct, run by the Nottingham Clinical Trials Unit… read more

Research Summary

Kirsty is a co-applicant on a number of NIHR Funded trials through the HTA and RfPB programmes:

Mountain G, Orrell M, Bowie P, Sprange K, Walters S, Craig C, Cooper C, Berry K, Blackburn D, Moniz-Cook ED, Young T. Journeying through dementia; randomised controlled trial of clinical and cost effectiveness. NIHR Health Technology Assessment Programme. 14/140/80. £2,017,925.

Sayal K, Montgomery AA, Sprange K, James M, Thomson L, Lang A, Ewart C, Reynolds S, Marshall T, Gledhill J, Dubicka B, Bhardwaj A. STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA): a multi-centre randomised controlled trial. NIHR Health Technology Assessment Programme. 16/96/09. £1,481,137.

Karantana K, Costa M, Davis T, James M, Jerosch-Herold C, Montgomery A, Ogollah R, Rodrigues J, Trickett R, Sprange K, Widdowson L. POINT: A multi-centre randomised trial of surgery versus non-surgical splint treatment for proximal phalanx shaft finger fractures in adults. NIHR Health Technology Assessment Programme. NIHR127292. £1,403,829.

Selected Publications

She is a lead for the Fundamentals of Clinical Trials course aimed at teaching the basics of clinical trial design and conduct, run by the Nottingham Clinical Trials Unit (

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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