Contact

• workRoom 2201 Floor C, South Block
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 82 31574
• Kirsty.Sprange@nottingham.ac.uk

Biography

I have worked for the Nottingham Clinical Trials Research Unit (NCTU) since May 2014 in the capacity of Trial Manager and then Senior Trial Manager. I now oversee a number of trials with a particular interest in mental health (dementia), rehabilitation medicine and hand surgery.

Prior to joining the NCTU I worked for the Sheffield Clinical Trials Research Unit (CTRU) where I managed several trials. These included an MRC programme grant evaluating an occupational therapy based psycho-social intervention for older people called Lifestyle Matters. This involved a randomised controlled trial to evaluate clinical and cost effectiveness as well as several feasibility studies in populations including people with early diagnosis dementia and mild to moderate depression. I also managed an NHIR HTA funded RCT and economic evaluation of hypertonic saline in acute bronchiolitis in babies (SABRE). Prior to joining the CTRU I worked for the Healthcare Innovation and Technology Evaluation Centre (HITEC) based at Derby Hospitals NHS Foundation Trust where I carried out systematic reviews, evidence reviews and technical evaluations of assistive technologies and medical devices for a number of commissioners. These included the Centre for Evidence-based Purchasing (CEP) part of the Purchasing and Supply Chain (PASA) and the National Institute for Health and Clinical Excellence (NICE).

Research Summary

Journeying through Dementia, Co-applicant on a £2m NIHR HTA CET Open Call to deliver an RCT of clinical and cost effectiveness (Dec 2015 - Feb 2019).

Selected Publications

• KIRSTY SPRANGE, GAIL A MOUNTAIN, KATY SHORTLAND, CLAIRE CRAIG, DANIEL BLACKBURN, PETER BOWIE, KIRSTY HARKNESS and MAGGIE SPENCER, 2015. Journeying through Dementia, a community-based self-management intervention for people aged 65 years and over: a feasibility study to inform a future trial Pilot and Feasibility Studies. 1(42),
• SPRANGE, KIRSTY, MOUNTAIN, GAIL A., BRAZIER, JOHN, COOK, SARAH P., CRAIG, CLAIRE, HIND, DANIEL, WALTERS, STEPHEN J., WINDLE, GILL, WOODS, ROBERT, KEETHARUTH, ANJU D., CHATER, TIM and HORNER, KATH, 2013. Lifestyle Matters for maintenance of health and wellbeing in people aged 65 years and over: study protocol for a randomised controlled trial TRIALS. 14(302),
• HIND, D, ROBERTS, C, SPRANGE, K, GOSSAGE-WORRALL, R, COOPER, C and WALTERS, S, 2013. Methodological, planning and implementation challenges for RCTs evaluating group interventions Trials. 14((Suppl 1)),
• SPRANGE, K and CLIFT, M, 2012. The NICE Medical Technologies Evaluation Programme (MTEP): manufacturer submission challenges Journal of the Royal Society of Medicine. 105(S4-S11),

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• ROBIN CHATTERS, LOUISE NEWBOLD, KIRSTY SPRANGE, DANIEL HIND, GAIL MOUNTAIN, KATY SHORTLAND, LAUREN POWELL, REBECCA GOSSAGE-WORRALL, TIM CHATER, ANJU KEETHARUTH, ELLEN LEE and BOB WOODS, 2018. Recruitment of older adults to three preventative lifestyle improvement studies Trials. 19(121),
• HARRISON E, TAN W, MILLS N, KARANTANA A, SPRANGE K, DULEY L, ELLIOTT D, BLAZEBY J, HOLLINGWORTH W, MONTGOMERY AA and DAVIS T, 2017. A feasibility study investigating the acceptability and design of a multicentre randomised controlled trial of needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren's contractures of the fingers (HAND-1): study protocol for a randomised controlled trial. Trials. 18(1), 392
• MOUNTAIN, GAIL, WINDLE, GILL, HIND, DANIEL, WALTERS, STEPHEN, KEERTHARUTH, ANJU, CHATTERS, ROBIN, SPRANGE, KIRSTY, CRAIG, CLAIRE, COOK, SARAH, LEE, ELLEN, CHATER, TIM, WOODS, R., NEWBOULD, LOUISE, POWELL, LAUREN, SHORTLAND, KATY and ROBERTS, JENNIFER, 2017. A preventative lifestyle intervention for older adults (lifestyle matters): a randomised controlled trial AGE AND AGEING. 46(4), 627-634
• ROBIN CHATTERS, JENNIFER ROBERTS, GAIL MOUNTAIN, SARAH COOK, GILL WINDLE, CLAIRE CRAIG and KIRSTY SPRANGE, 2017. The long-term (24-month) effect on health and well-being of the Lifestyle Matters community-based intervention in people aged 65 years and over: a qualitative study BMJ Open.
• KIRSTY SPRANGE, GAIL A MOUNTAIN, KATY SHORTLAND, CLAIRE CRAIG, DANIEL BLACKBURN, PETER BOWIE, KIRSTY HARKNESS and MAGGIE SPENCER, 2015. Journeying through Dementia, a community-based self-management intervention for people aged 65 years and over: a feasibility study to inform a future trial Pilot and Feasibility Studies. 1(42),
• EVERARD, MARK L., HIND, DANIEL, UGONNA, KELECHI, FREEMAN, JENNIFER, BRADBURN, MIKE, COOPER, CINDY L., CROSS, ELIZABETH, MAGUIRE, CHIN, CANTRILL, HANNAH, ALEXANDER, JOHN and MCNAMARA, PAUL S., 2014. SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis THORAX. 69(12), 1105-1112
• SPRANGE, KIRSTY, MOUNTAIN, GAIL A., BRAZIER, JOHN, COOK, SARAH P., CRAIG, CLAIRE, HIND, DANIEL, WALTERS, STEPHEN J., WINDLE, GILL, WOODS, ROBERT, KEETHARUTH, ANJU D., CHATER, TIM and HORNER, KATH, 2013. Lifestyle Matters for maintenance of health and wellbeing in people aged 65 years and over: study protocol for a randomised controlled trial TRIALS. 14(302),
• HIND, D, ROBERTS, C, SPRANGE, K, GOSSAGE-WORRALL, R, COOPER, C and WALTERS, S, 2013. Methodological, planning and implementation challenges for RCTs evaluating group interventions Trials. 14((Suppl 1)),
• SPRANGE, K and CLIFT, M, 2012. The NICE Medical Technologies Evaluation Programme (MTEP): manufacturer submission challenges Journal of the Royal Society of Medicine. 105(S4-S11),