I joined the Nottingham Digestive Disease Centre (NDDC), located in the QMC, in November 2019 and since then have provided statistical advice to a number of projects including investigating the effect of new cystic fibrosis therapies on gastrointestinal outcomes via the use of MRI, and a meta-analysis of non-invasive markers and their ability to predict mortality in patients with NAFLD.
In February 2020 I registered for a PhD in Epidemiology. The topic is about non-invasive, indirect markers of liver function such as the ALT and AST, and whether composite measures (such as the AST/ALT ratio, APRI and FIB-4) that include these and other factors are accurate enough or can be improved upon, to be provide reliable diagnoses of advanced liver disease, such as cirrhosis and hepatocellular carcinoma.
Before joining the NDDC I worked as a Research Statistician in the Division of Primary Care, where I mainly worked on drug safety studies that used data from the QResearch database. These studies investigated the association between certain types of drug and adverse outcomes. For example, antidepressant use and the risk of epilepsy and anticholinergic drugs and the risk of dementia.
Prior to this I worked for approximately sixteen years for the University of Leicester as a Research Technician in the Department of Psychiatry. Whilst at Leicester I studied part-time for a Master's degree in Medical Statistics, which I completed in 2006 and was awarded a Merit. I also have a first degree in Computer Systems Engineering from the University of Warwick.
COUPLAND, C.A.C., HILL, T., DENING, T., MORRISS, R., MOORE, M. and HIPPISLEY-COX, J., 2019. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control StudyAnticholinergic Drug Exposure and the Risk of DementiaAnticholinergic Drug Exposure and the Risk of Dementia JAMA Internal Medicine. 179(8), 1084-1093 COUPLAND, C., HILL, T., MORRISS, R., MOORE, M., ARTHUR, A. and HIPPISLEY-COX, J., 2018. Antidepressant use and risk of adverse outcomes in people aged 20 to 64: cohort study using a primary care database. BMC Medicine. 16(1), 36
KENDRICK, D., BAKER, R., HILL, T., BECKETT, K., COUPLAND, C., KELLEZI, B., JOSEPH, S., BARNES, J., SLENEY, J., CHRISTIE, N. and MORRISS, R., 2018. Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: Multicentre cohort study Journal of Psychosomatic Research. 112, 15-24