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Professor and Honorary Consultant, Faculty of Medicine & Health Sciences
We have explored the therapeutic benefit of increasing the dose of inhaled steroids to prevent the development of asthma exacerbations.
We are currently exploring the mechanisms for therapy resistant asthma and looking at new therapeutic options for these patients
We have explored the absorption and systemic effects of inhaled steroids in asthma and COPD and explored the effect of lung function.
We are now able to evaluate airway inflammation using multi-flow exhaled NO meters, induced sputum and various airway challenges. research exploring asthma phenotypes and the development of the new treatments are of interest.
Airway phenotyping includes human airway smooth muscle and epithelial cell culture for in-vitro work.