Professor in Stroke Medicine & Honorary Consultant Physician (Royal Derby Hospital)
My undergraduate medical years were at the University of Leicester (1996 - 2001) and I trained in Health Care for the Elderly and General Internal Medicine (Nottingham University Hospitals, CCT 2011) during which time I obtained a PhD in Stroke Medicine at the University of Nottingham.
My research interests embrace the hyperacute phase of stroke, assessing potential treatments such as remote ischaemic pre- per and post-conditioning; the role of cannabinoids in the vasculature and blood brain barrier; post-stroke dysphagia recovery; and blood pressure and stroke. I am the Chief Investigator for the RECAST trials and support various clinical studies through the Nottingham Stroke Trials Unit, currently including TICH-3 and PhEAST. I'm additionally interested in the impact of frailty on treatments used in stroke, running an East-Midlands based frailty cohort study FINE-ST. I am the NIHR CRN East Midlands Lead for Stroke.
I provide regular teaching and training at both undergraduate and post-graduate levels. Specific roles include lectures and seminars to Undergraduate and Graduate Entry Medical (GEM) Students; BSc… read more
I am a clinical trialist in Stroke and the Chief Investigator of the RECAST trials (Remote Ischaemic Conditioning After Stroke) . Other active interests include the effects of cannabinoids on… read more
LAW ZK, ENGLAND TJ, MISTRI AK, WOODHOUSE L, CALA L, ET AL and TICH-2 INVESTIGATORS, 2020. Incidence and predictors of early and late seizures in intracerebral haemorrhage European Stroke Journal. 0(0), 1-7
WEIR P, MAGUIRE R, O'SULLIVAN S and ENGLAND TJ, 2020. A Meta-analysis of Remote Ischaemic Conditioning in Experimental Stroke J Cereb Blood Flow Metab. 41(1), 32538284
I provide regular teaching and training at both undergraduate and post-graduate levels. Specific roles include lectures and seminars to Undergraduate and Graduate Entry Medical (GEM) Students; BSc Cardiovascular Module seminars, exam question generation and marking; Clinical Phase (CP) 3 and MAST student supervision; facilitating Problem Based Learning (Cardiovascular Module); regular bedside teaching CP1 and CP3 students; examining end of year CP1 and CP3 students; personal tutor to GEM students
I am a clinical trialist in Stroke and the Chief Investigator of the RECAST trials (Remote Ischaemic Conditioning After Stroke) . Other active interests include the effects of cannabinoids on haemodynamics, treatment for post-stroke dysphagia and meta-analysis (pre-clinical and clinical).
I sit on the Trial Steering Committees (TSC) for LACI-2 (LACunar Intervention Trial-2), TICH-3 (Tranexamic acid in Intracerebral Haemorrhagic), and PhEAST (Pharyngeal Electrical stimulation for Acute Stroke dysphagia Trial). Previous trial steering committees include TICH-2, RIGHT-2 (Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2) and BEADS (BEhavioural Activation therapy for Depression after Stroke).
I am the East Midlands NIHR CRN lead for Stroke. I am an expert reviewer for the NIHR, NICE and contribute to the National Clinical Guideline for Stroke in the UK and Ireland.