Professor in Stroke Medicine & Honorary Consultant Physician (Royal Derby Hospital)
My undergraduate medical years were at the University of Leicester (1996 - 2001) and I trained in Health Care for the Elderly and General Internal Medicine (Nottingham University Hospitals, CCT 2011) during which time I obtained a PhD in Stroke Medicine at the University of Nottingham.
My research interests embrace the hyperacute phase of stroke, assessing potential treatments such as remote ischaemic pre- per and post-conditioning; the role of cannabinoids in the vasculature and blood brain barrier; post-stroke dysphagia recovery; and blood pressure and stroke. I am the Chief Investigator for the RECAST trials and support various clinical studies through the Nottingham Stroke Trials Unit, currently including TICH-3 and PhEAST. I'm additionally interested in the impact of frailty on treatments used in stroke, running an East-Midlands based frailty cohort study FINE-ST. I am the NIHR CRN East Midlands Lead for Stroke.
I provide regular teaching and training at both undergraduate and post-graduate levels. Specific roles include lectures and seminars to Undergraduate and Graduate Entry Medical (GEM) Students; BSc… read more
I am a clinical trialist in Stroke and the Chief Investigator of the RECAST trials (Remote Ischaemic Conditioning After Stroke) . Other active interests include the effects of cannabinoids on… read more
PSZCZOLKOWSKI S, SPRIGG N, WOODHOUSE LJ, GALLAGHER R, SWIENTON D, LAW ZK, CASADO AM, ROBERTS I, WERRING DJ, AL-SHAHI SALMAN R, ENGLAND TJ, MORGAN PS, BATH PM and DINEEN RA, 2022. Remote Cerebral Ischaemic Lesions After Tranexamic Acid For Acute Spontaneous Intracerebral Haemorrhage JAMA Neurol. 79(5), 468-477 PODLASEK A, DHILLON PS, BUTT W, GRUNWALD IQ and ENGLAND TJ, 2022. To bridge or not to bridge: summary of the new evidence in endovascular stroke treatment Stroke Vasc Neurol. 7(3), 179-181 DHILLON PS, BUTT W, PODLASEK A, BARRETT E, MCCONACHIE N, LENTHALL R, NAIR S, MALIK L, JAMES MA, DINEEN RA and ENGLAND TJ, 2022. Endovascular Thrombectomy Beyond 24 Hours From Ischaemic Stroke Onset: A Propensity Score-Matched Cohort Study J Neurointerv Surg. neurintsurg-2021-018591
MAGUIRE RF, WILKINSON DJ, ENGLAND TJ and O'SULLIVAN SE, 2021. The Pharmacological Effects of Plant-Derived versus Synthetic Cannabidiol in Human Cell Lines Med Cannabis Cannabinoids. 4, 86-96
I provide regular teaching and training at both undergraduate and post-graduate levels. Specific roles include lectures and seminars to Undergraduate and Graduate Entry Medical (GEM) Students; BSc Cardiovascular Module seminars, exam question generation and marking; Clinical Phase (CP) 3 and MAST student supervision; facilitating Problem Based Learning (Cardiovascular Module); regular bedside teaching CP1 and CP3 students; examining end of year CP1 and CP3 students; personal tutor to GEM students
I am a clinical trialist in Stroke and the Chief Investigator of the RECAST trials (Remote Ischaemic Conditioning After Stroke) . Other active interests include the effects of cannabinoids on haemodynamics, treatment for post-stroke dysphagia and meta-analysis (pre-clinical and clinical).
I sit on the Trial Steering Committees (TSC) for LACI-2 (LACunar Intervention Trial-2), TICH-3 (Tranexamic acid in Intracerebral Haemorrhagic), and PhEAST (Pharyngeal Electrical stimulation for Acute Stroke dysphagia Trial). Previous trial steering committees include TICH-2, RIGHT-2 (Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2) and BEADS (BEhavioural Activation therapy for Depression after Stroke).
I am the East Midlands NIHR CRN lead for Stroke. I am an expert reviewer for the NIHR, NICE and contribute to the National Clinical Guideline for Stroke in the UK and Ireland.