MONAGHAN, TANYA M., COCKAYNE, ALAN and MAHIDA, YASHWANT R., 2015. Pathogenesis of Clostridium difficile Infection and Its Potential Role in Inflammatory Bowel Disease INFLAMMATORY BOWEL DISEASES. 21(8), 1957-1966 HIGGINS, J., MUTAMBA, S., MAHIDA, Y., BARROW, P.A. and FOSTER, N.,, 2015. IL-36 alpha induces maturation of Th1-inducing human MDDC and synergises with IFN-gamma to induce high surface expression of CD14 and CD11c Human Immunology. 76(4), 245-253 BROWN, M., HUGHES, K. R., MOOSSAVI, S., ROBINS, A. and MAHIDA, Y. R., 2014. Toll-like receptor expression in crypt epithelial cells, putative stem cells and intestinal myofibroblasts isolated from controls and patients with inflammatory bowel disease CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 178(1), 28-39 MONAGHAN, TANYA M., ROBINS, ADRIAN, KNOX, ALAN, SEWELL, HERBERT F. and MAHIDA, YASHWANT R., 2013. Circulating Antibody and Memory B-Cell Responses to C. difficile Toxins A and B in Patients with C. difficile-Associated Diarrhoea, Inflammatory Bowel Disease and Cystic Fibrosis PLOS ONE. 8(9), HUGHES, K.R., GÂNDARA, R.M.C., JAVKAR, T., SABLITZKY, F., HOCK, H., POTTEN, C.S. and MAHIDA, Y.R., 2012. Heterogeneity in histone 2B-green fluorescent protein-retaining putative small intestinal stem cells at cell position 4 and their absence in the colon. Am J Physiol Gastrointest Liver Physiol. 303(11), G1188-1201 GANDARA, RMC, MAHIDA, YR and POTTEN, CS, 2012. Regional Differences In Stem And Transit Cell Proliferation And Apoptosis In The Terminal Ileum And Colon Of Mice After 12 Gy International Journal Of Radiation Oncology Biology Physics. 82(3), E521-E528 MUTAMBA, S., ALLISON, A., MAHIDA, Y., BARROW, P. and FOSTER, N., 2011. Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9 European Journal of Immunology. 42(3), 607-17 MODI, N., GULATI, N., SOLOMON, K., MONAGHAN, T., ROBINS, A., SEWELL, H.F. and MAHIDA, Y.R., 2011. Differential binding and internalization of clostridium difficile toxin A by human peripheral blood monocytes, neutrophils and lymphocytes Scandinavian Journal of Immunology. 74(3), 264-271 WALSH, R, SETH, R, BEHNKE, J, POTTEN, C S and MAHIDA, Y R, 2009. Epithelial stem cell-related alterations in Trichinella spiralis-infected small intestine. Cell Proliferation. 42(3), 394-403 SAMUEL, S., WALSH, R., WEBB, J., ROBINS, A., POTTEN, C. and MAHIDA, Y.R., 2009. Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interactions with myofibroblasts American Journal of Physiology: Cell Physiology. 296(2), C296-C305 POTTEN, C S, GANDARA, R, MAHIDA, Y R, LOEFFLER, M and WRIGHT, N A, 2009. The stem cells of small intestinal crypts: where are they? Cell proliferation. 42(6), 731-50 MONAGHAN, T., BOSWELL, T. and MAHIDA, Y.R., 2008. Recent advances in Clostridium difficile-associated disease Gut. 57(6), 850-860 MAHIDA YR and MORAN GW, 2008. Do non-immune cells have a role in IBD? Inflammatory bowel diseases. 14 Suppl 2, S123-4 SUTTON, P A, LI, S, WEBB, J, SOLOMON, K, BRAZIER, J and MAHIDA, Y R, 2008. Essential role of toxin A in C. difficile 027 and reference strain supernatant-mediated disruption of Caco-2 intestinal epithelial barrier function. Clinical and experimental immunology. 153(3), 439-47 SUNDBOM, M, ELPHICK, D A, MAHIDA, Y R, CUNLIFFE, R N, MIDTVEDT, T, ENGSTRAND, L, RUBIO, C and AXELSSON, L GÖRAN, 2007. Alteration in human defensin-5 expression following gastric bypass surgery. Journal of clinical pathology. 60(9), 1029-34 SOLOMON, K., WEBB, J., ALI, N., ROBINS, R. A. and MAHIDA, Y. R., 2005. Monocytes Are Highly Sensitive to Clostridium difficile Toxin A-Induced Apoptotic and Nonapoptotic Cell Death Infection and Immunity. VOL 73(NUMB 3), 1625-1634 AUSTIN, A.S., JUDGE, H.M., ROBINS, R.A., COCKAYNE, A. and MAHIDA, Y.R., 2005. Responses to free lipopolysaccharide and Escherichia coli by normal human intestinal macrophages, following their migration out of the lamina propria Scandinavian Journal of Immunology. 61(6), 575-584 JOHAL, S.S., HAMMOND, J., SOLOMON, K., JAMES, P.D. and MAHIDA, Y.R., 2004. Clostridium difficile associated diarrhoea in hospitalised patients: onset in the community and hospital and role of flexible sigmoidoscopy Gut. 53(5), 673-677 JOHAL, S. S., SOLOMON, K., DODSON, S., BORRIELLO, S.P. and MAHIDA, Y.R., 2004. Differential effects of varying concentrations of clostridium difficile toxin A on epithelial barrier function and expression of cytokines. The Journal of infectious diseases. 189(11), 2110-2119 JOHAL, S.S., LAMBERT, C.P., HAMMOND, J., JAMES, P.D., BORRIELLO, S.P. and MAHIDA, Y.R., 2004. Colonic IgA producing cells and macrophages are reduced in recurrent and non-recurrent Clostridium difficile associated diarrhoea Journal of Clinical Pathology. 57(9), 973-979 AUSTIN, A.S., MAHIDA, Y.R., CLARKE, D., RYDER, S.D. and FREEMAN, J.G., 2004. A pilot study to investigate the use of oxpentifylline (pentoxifylline) and thalidomide in portal hypertension secondary to alcoholic cirrhosis Alimentary Pharmacology and Therapeutics. 19(1), 79-88 MAHIDA, Y.R. and CUNLIFFE, R.N., 2004. Defensins and mucosal protection Novartis Foundation Symposium. 263, 71-7; discussion 77-84, 211-8
MAHIDA, Y.R. and ROLFE, V.E., 2004. Host-bacterial interactions in inflammatory bowel disease Clinical Science. 107(4), 331-341 CUNLIFFE, R.N. and MAHIDA, Y.R., 2004. Expression and regulation of antimicrobial peptides in the gastrointestinal tract Journal of Leukocyte Biology. 75(1), 49-58 MAHIDA, Y.R., 2004. Microbial-gut interactions in health and disease: epithelial cell responses Best Practice & Research Clinical Gastroenterology. 18(2), 241-253
SOLOMON, K., ROBINS, R.A. and MAHIDA, Y.R., 2003. C difficile toxin A induces rapid and selective monocyte cell death Gut. 52, 199
MAHIDA, Y.R., 2003. Host-parasite interactions in rodent nematode infections Journal of Helminthology. 77(2), 125-131 SKELLY, M.M., LOGAN, R.F.A., JENKINS, D., MAHIDA, Y.R. and HAWKEY, C.J., 2002. Toxicity of mycophenolate mofetil in patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 8(2), 93-97 MCKAIG, B.C., HUGHES, K., TIGHE, P.J. and MAHIDA, Y.R., 2002. Differential expression of TGF-β isoforms by normal and inflammatory bowel disease intestinal myofibroblasts American Journal of Physiology: Cell Physiology. 282(1), C172-C182 JOHAL, S.S., SOLOMON, K., WEBB, J., DODSON, S. and MAHIDA, Y.R., 2002. Changes in epithelial barrier and cytokine release in response to C-difficile toxin A Gut. 50, 255
CUNLIFFE, R.N., KAMAL, M., ROSE, F.R.A.J., JAMES, P.D. and MAHIDA, Y.R., 2002. Expression of antimicrobial neutrophil defensins in epithelial cells of active inflammatory bowel disease mucosa Journal of Clinical Pathology. 55(4), 298-304 AUSTIN, A.S., ROBINS, A. and MAHIDA, Y.R., 2002. Characterisation of the expression of toll-like receptor (TLR) 2, TLR 4, CD14 and responsiveness to lipopolysaccharide (LPS) by intestinal macrophages Gastroenterology. 122(4), M1099
AUSTIN, A.S., ROBINS, R., RYDER, S.D. and MAHIDA, Y.R., 2002. Rapid upregulation of toll-like receptor (TLR) 4 and tumour necrosis factor alpha (TNF-alpha) expression in lipopolysaccharide (LPS) stimulated monocytes in whole blood in alcoholic cirrhosis Gastroenterology. 122(4), M822
CIACCI, C., DI VIZIO, D., SETH, R., INSABATO, G., MAZZACCA, G., PODOLSKY, D.K. and MAHIDA, Y.R., 2002. Selective reduction of intestinal trefoil factor in untreated coeliac disease. Clinical and Experimental Immunology. 130(3), 526-31 CUNLIFFE, R.N., ROSE, F.R.A.J., KEYTE, J., ABBERLEY, L., CHAN, W.C. and MAHIDA, Y.R., 2001. Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease Gut: Journal of the British Society of Gastroenterology. 48(2), 176-185 KAMAL, M, WAKELIN, D, OUELLETTE, A J, SMITH, A, PODOLSKY, D K and MAHIDA, Y R, 2001. Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice. Clinical and Experimental Immunology. 126(1), 117-25 ELLABBAN, W., TIGHE, P., MCKAIG, B.C., ROBINS, A., GALVIN, A., SEWELL, H.F. and MAHIDA, Y.R., 2001. Migration of precursors of intraepithelial lymphocytes (IELs) from human colonic lamina propria (LP) Gut. 48, 285
ELLABBAN, W., TIGHE, P., MCKAIG, B.C., ROBINS, A., GALVIN, A., SEWELL, H.F. and MAHIDA, Y.R., 2001. Migration of precursors of intraepithelial lymphocytes (IELs) from human colonic lamina propria Gastroenterology. 120(5), 1644 AUSTIN, A.S., MAHIDA, Y.R., RYDER, S.D. and FREEMAN, J.G., 2001. Thalidomide but not pentoxifylline lowers portal pressure in human alcoholic cirrhosis Journal of Hepatology. 34(Supp 1), 18
KAMAL, M., WAKELIN, D. and MAHIDA, Y., 2001. Mucosal responses to infection with Trichinella spiralis in mice. Parasite-Journal De La Societe Francaise De Parasitologie. 8(2 Suppl), S110-3 WU, K.C., JACKSON, L.M., GALVIN, A.M., GRAY, T., HAWKEY, C.J. and MAHIDA, Y.R., 1999. Phenotypic and functional characterisation of myofibroblasts, macrophages, and lymphocytes migrating out of the human gastric lamina propria following the loss of epithelial cells Gut. 44(3), 323-330 COUTINHO, H.B., CARMONA DA MOTA, H., COUTINHO, V.B., ROBALINHO, T.I., FURTADO, A.F., WALKER, E., KING, G., MAHIDA, Y.R., SEWELL, H.F. and WAKELIN, D., 1998. Absence of lysozyme (muramidase) in the intestinal Paneth cells of newborn infants with necrotising enterocolitis Journal of Clinical Pathology. 51(7), 512-514 GALVIN,A., MAHIDA,Y.R., PODOLSKY,D.K., SEWELL,H.F., MCALINDON,M.E. and GRAY,T., 1998. Differential lamina propria cell migration via basement membrane pores of inflammatory bowel disease mucosa Gastroenterology. 115(4), 841-848 LI, C.K.F., SETH, R., GRAY, T., BAYSTON, R., MAHIDA, Y.R. and WAKELIN, D., 1998. Production of proinflammatory cytokines and inflammatory mediators in human intestinal epithelial cells after invasion by Trichinella spiralis Infection and Immunity. 66(5), 2200-2206
ISHIKAWA, N., GOYAL, P.K., MAHIDA, Y.R., LI, K.-F. and WAKELIN, D., 1998. Early cytokine responses during intestinal parasitic infections Immunology. 93(2), 257-263 SANFILIPPO, L., BALDWIN, T.J., MENOZZI, M.G., BORRIELLO, S.P. and MAHIDA, Y.R., 1998. Heterogeneity in responses by primary adult human colonic epithelial cells to purified enterotoxin of Bacteroides fragilis Gut. 43(5), 651-655 MAHIDA, Y.R., ROSE, F. and CHAN, W.C., 1997. Antimicrobial peptides in the gastrointestinal tract Gut. 40(2), 161-163
MAHIDA, Y.R., BELTINGER, J., MAKH, S., GÖKE, M., GRAY, T., PODOLSKY, D.K. and HAWKEY, C.J., 1997. Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2 American Journal of Physiology. 273(6 Pt 1), G1341-8
MAHIDA, Y.R., MAKH, S., HYDE, S., GRAY, T. and BORRIELLO, S.P., 1996. Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and apoptosis after cell detachment Gut. 38(3), 337-347