20% of the UK population attendances in primary care for musculoskeletal conditions (£5b NHS spend each year) are due to age-related musculoskeletal diseases. With associated comorbidities (cardiovascular, metabolic, obesity, neurological, mental health), these increasingly threaten independence and challenge healthcare budgets.
The multidisciplinary NIHR Nottingham Biomedical Research Centre Musculoskeletal Theme investigates ways of preventing and treating musculoskeletal problems.
To provide a platform for translating outputs from our world-class discovery science programmes to improve quality of life and sustain people more effectively in the community. We will achieve this by using our comprehensive mechanistic understanding and novel biochemical, imaging and clinical technologies to develop and evaluate novel interventions matched to individuals, leading to a personalised medicine approach, linked to improved mechanistic understanding.
The musculoskeletal theme is split into five research areas:
The interdisciplinary musculoskeletal theme is based across multiple sites, including the Clinical Sciences Building with its dedicated clinic rooms, a specialised physiotherapy room, range of assessment tools (Muscle strength test, Hand Grip assessment, Quantitative Sensory Testing, Ultrasound, GAITRite portable gait analysis system, RS Scan balance test, validated questionnaires), and state-of-the-art laboratories.
The University of Nottingham has world leading facilities for human physiology based investigations located in state-of-the-art human physiology laboratories within the School of Medicine on the Queen’s Medical Centre campus and the satellite Medical Sciences and Graduate Entry Medicine on the Derby campus. These sites include a clinical trials ward, exercise and resting metabolism laboratories, gymnasium for resistance training and volunteer screening rooms. World-leading whole-body MRI facilities or human imaging and spectroscopy are available in the Sir Peter Mansfield Imaging Centre.
The musculoskeletal theme dovetails institutional research priorities intranslational imaging and musculoskeletal health in ageing and well-being.Further, it complements existing institutional and cross-council investments,i.e. the interdisciplinary MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, the Arthritis Research UK Pain Centre, the Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, and the Sir Peter Mansfield Imaging Centre.
Professor David Walsh: Musculoskeletal Theme Lead/ Phenotyping and outcome measurement research area co-lead Research interests
Professor Dorothee Auer: Imaging Cross cutting Theme Lead/ Phenotyping and outcome measurement research area co-lead Research interests
Professor Victoria Chapman: The joint research area lead Research interests
Dr Ana Valdes: The brain research area lead Research interests
Professor John Gladman: Complex treatment packages research area co-lead Research interests
Professor Michael Doherty: Complex treatment packages research area co-lead Research interests
Professor Paul Greenhaff: Metabolism research area lead Research interests
Clinical Sciences BuildingCity HospitalNottingham, NG5 1PB
telephone: +44 (0) 115 823 1766 ext 31766
fax: +44 (0) 115 823 1757
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