• Testing DGHPU

    David Greenfield 

    Human Physiology Unit

     

    Our outstanding research expertise, exercise and clinical research facilities are housed in the David Greenfield Human Physiology Unit (DGHPU) in the Division of Physiology, Pharmacology, and Neuroscience of The School of Life Sciences. 

    Officially opened in September 2008 by Prof. Eric Hultman, the DGHPU has since been the hub for physiology, nutrition and metabolism research at the University of Nottingham. Our highly skilled team of academic researchers, clinical fellows, and specialist research technicians, provide us with the capabilities to deliver world leading' and 'internationally excellent' research into metabolic and physiological regulation in studies involving human volunteers.

    Useful Links

    Meet the team

    Current studies

    Teaching facilities

    How to find us

     

     

    David Greenfield Human Physiology Unit

    Location: Medical School, Queen's Medical Centre (B7)

    Our bespoke in vivo human research unit houses:

    • Exercise Physiology Laboratories
    • Temperature controlled resting metabolism and nutrition laboratories
    • Biological Sample Preparation Laboratory
    • Screening Rooms
    • Dual Energy X-ray Absorptiometry Facility (DXA)
    • Research Gym
    • Nutrition Kitchen
     
    Some of our equipment includes:
    • Isokinetic cycle ergometers 
    • Motor driven treadmills allowing for incline and decline exercise.
    • Magnetic Resonance-compatible ergometers (for small and large muscle group investigation)
    • Breath-by-breath indirect calorimeters
    • Ventilated hood indirect calorimeters
    • Isokinetic resistance exercise dynamometers
    • Intramuscular electromyography
    • High-spec ultrasound machines
    • Rapid response venous and capillary blood sample analysers for determination of lactate, glucose, lipid profile, creatine kinase, haemoglobin, haematocrit and blood gases
    • Automated blood pressure, ECG and pulse oximetry monitors
    • Heart Rate and Physical activity monitors
    • Chilled centrifuges
    • Equipment for muscle, fat and blood processing
    • Microscopes for single muscle fibre isolation
    • Sample storage
     
    Our capabilities include:
    • Hyperinsulinaemic euglycaemic clamps
    • Intravenous infusion and oral administration of nutrients and stable isotopes of amino acids, fatty acidds and glucose
    • Short term bed rest and immobilisation studies
    • Resting metabolism measures in longitudinal exercise training and nutritional intervention studies
    • Acute nutritional interventions
    • Bergstrom needle muscle biospy, Bard micro-biopsy muscle sampling and adipose fat sampling
    • Plethysmography
     
     

    Experimental Medicine, Metabolic and Nutritional Physiology Research Group

    David Greenfield Human Physiology Unit
    School of Life Sciences
    Medical School
    University of Nottingham
    Nottingham, NG7 2UH