Our Exercise Physiology Laboratories are equipped with:

• Isokinetic cycle ergometers 
• Motor driven treadmills allowing for incline and decline exercise.
• Magnetic Resonance-compatible ergometers (for small and large muscle group investigation)
• Breath-by-breath indirect calorimeters
• Isokinetic resistance exercise dynamometers
• Intramuscular electromyography
• Rapid response venous and capillary blood sample analysers for determination of lactate, glucose, lipid profile, creatine kinase, haemoglobin, haematocrit and blood gases
• Automated blood pressure, ECG and pulse oximetry monitors
• Heart Rate and Physical activity monitors

Laboratories consisting of:

• Five-bed resting metabolism ward equipped with ventilated hood indirect calorimeters, high-spec ultrasound machines, finometry and blood analysers.
• Temperature controlled resting metabolism and nutrition laboratory. 

These laboratories have the capability to conduct: 

• Hyperinsulinaemic euglycaemic clamps
• Intravenous infusion and oral administration of nutrients and stable isotopes of amino acids, fatty acidds and glucose
• Short term bed rest and immobilisation studies
• Resting metabolism measures in longitudinal exercise training and nutritional intervention studies
• Acute nutritional interventions
• Bergstrom needle muscle biospy, Bard micro-biopsy muscle sampling and adipose fat sampling
• Plethysmography

Sample preparation laboratory allows for processing of blood, saliva, and muscle for subsequent analysis. 

This lab is equipped with:

• Chilled centrifuges
• Facilities for muscle, fat and blood processing
• Microscopes for single muscle fibre isolation
• Sample storage

Our laboratories are equipped to provide capability for:

• General protein, DNA and RNA quantification using in-house extraction assays and Spectroscopy (Visible and UV). 

• Specific protein quantification (detecting changes in the levels of specific protein molecules among a mixture of proteins) using Western blotting. 

• Gene expression analysis (detecting changes in the level of expression of specific genes) using Real-time PCR. 

• Live cell imaging (studying living cells over some time) and Fixed Cell imaging (studying lipid accumulation in muscle cells) using Fluorescence Microscopy. 

• Substrate and metabolite analysis using a variety of techniques including spectrophotometry, fluorimetry, ELISAs, magnetic bead flow cytometry, and in-house radiochemical assays. 

• Mitochondrial respiration measurements using respirometry and luminescence.