GI and Liver Diseases Medical and Surgical Research

ASTIC Trial - Centres and Members

Chief Investigator

Professor Chris Hawkey
Nottingham Digestive Diseases Centre (ASTIC study administration office)
Tel: +44 (0)115 82 31031
Fax: +44 (0)115 94 22232

Sponsors and support

European Group for Blood and Marrow Transplantation (EBMT)

This study is sponsored by the European Group for Blood and Marrow Transplantation (EBMT). The EBMT is a non-profit organisation based in Maastricht, The Netherlands, that was established in 1974 in order to allow scientists and physicians involved in clinical bone marrow transplantation to share their experience and develop co-operative studies. The EBMT aims to promote all aspects associated with the transplantation of haematopoietic stem cells from all donor sources and donor types including basic and clinical research, education, standardisation, quality control, and accreditation for transplant procedures.


European Crohn's and Colitis Organization (ECCO)

The study is being conducted by the European Crohn's and Colitis Organization (ECCO). ECCO is the umbrella organization of the national study groups performing and coordinating research work in the field of inflammatory bowel disease (IBD).


Nottingham Digestive Diseases Centre

Broad Medical Research Programme

The study is funded by a grant from the Broad Medical Research Programme, created by The Eli and Edythe L. Broad Foundation. The programme provides funds for innovative basic and clinical research that will lead to improvements in the diagnosis, therapy and prevention of Crohn's disease and ulcerative colitis.



Participating countries

In each of the countries where the trial is conducted, a Country Chief Investigator has been identified. This investigator should be the first point of contact for doctors in that country who are interested in finding out more about the study. 

The participating countries are: Belgium, Canada, Czech Republic, France, Germany, Italy, Netherlands, Spain, Switzerland, United Kingdom.


Country Chief Investigators:
Dr Séverine Vermeire (Gastroenterologist)
Dr Daan Dierickx (Haematologist)
University Hospital Gasthuisberg
Herestraat 49, 3000 Leuven


Country Chief Investigators:
Dr Michelle Geddes (Gastroenterologist)
Foothills Medical Centre
1403-29 St NW Calgary
Alberta T2N 2T9

Participating investigators:
Dr Jan Storek (Haematologist)
Dr Paul Beck (Haematologist)
Foothills Medical Centre

Dr Richard Fedorak (Gastroenterologist)
Zeidler Ledcor Centre
130 University Campus
Alberta T6G 2X8

Czech Republic

Country Chief Investigators:
Professor Milan Lukas (Gastroenterologist)
IVth Medical Dept
General Faculty Hospital
Prague 2 120 00

Dr Pohlreich (Haematologist)
Institute of Haematology and Blood Transfusion
U nemocnice 2, Prague 


Country Chief Investigators:
Professor Dominique Farge (Transplantor)
Service de Medecine Interne
Hospital St. Louis
1 Avenue Claude Vellefaux
75010 Paris

Participating Investigators:
Professor Jean-Frederic Colombel (Gastroenterologist)
Dr David Seguy (Gastroenterologist)
Pr Jouet (Haematologist)
Hopital Huriez Chru
Lille 59037

Pr Matthieu Allez (Gastroenterologist)
Hopital St Louis
75010 Paris


Country Chief Investigators:
Pr Renate Arnold (Haematologist)
Dr Daniel Baumgart (Gastroenterologist)
Pr Martin Zeitz (Gastroenterologist)
Charite Universitatsmedizin Berlin 


Country Chief Investigators:
Professor Paolo Gionchetti (Gastroenterologist)
Division of Gastroenterology
University of Bologna
Professor Riccardo Saccardi (Transplantor)
Dept of Haematology
University Hospital
Via le Morgagni 85

Participating Investigators:
Dr Silvio Danese (Gastroenterologist)
Dr Ibatici (Haematologist)
Istituto Clinico Humanitas
Via Manzoni 56
20089 Rozzano

Dr Sandro Ardizzone (Gastroenterologist)
L Sacco University Hospital
Via GB Grassi 74
20157 Milan

Dr Francesco Onida (Haematologist)
Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli e Regina Elena
Via Francesco Sforza 35
20122 Milan

Drs Pallone/Biancone.Caprilli (Gastroenterologist)
Dr Giorgio Arcese (Haemotologist)
University of Rome

Dr Monica Milla (Gastroenterologist)
Dr Riccardo Saccardi (Haemotologist)
Careggi Hospital

Drs Rizzello/Campier (Gastroenterologist)
Dr Michelle Baccarani (Haematologist)
University of Bologna

Dr Mario Cottone (Gastroenterologist)
University of Palermo

Dr Fabrizio Bossa (Gastroenterologist)
Dr Nicola Cascavilla (Haemotologist)
CSS Hospital
San Giovani Rotondo

Drs Zelante/Gullini (Gastroenterologist)
Dr Francesco Lanza (Haemotologist)
St Anna Hospital



Country Chief Investigators:
Professor Daan Hommes (Gastroenterologist)
Dept of Gastroenterology
Albinusdreef 2
2333ZA Leiden 


Country Chief Investigators:
Professor Julian Panes
Dr Elena Ricart (Gastroenterologist)
Dr Enric Carreras (Haemotologist)
Hospital Clinic
C/Villarroel 170


Country Chief Investigator:
Professor Christoph Beglinger (Gastroenterologist)
Prof. Dr Alois Gratohl (Transplanter)
University Hospital
CH-4031 Basel

Participating Investigator:
Pr Pierre Michetti (Gastroenterologist)
Centre Hospitalier Universitaire Vaudois
Ch-1101 Lausanne

Dr Gerhard Rogler (Gastroenterologist)
Urs Schanz 4 (Haemotologist)
UniversitatsSpital Zurich
8091 Zurich

United Kingdom

Country Chief Investigators:
Professor Chris Hawkey (Gastroenterologist)
Nottingham Digestive Diseases Centre
University Hospital
Nottingham NG7 2UH, UK

Participating Investigators:
Dr Nigel Russell (Haemotologist)
Nottingham City Hospital
Nottingham NG5 1PB

Dr Simon Travis (Gastroenterologist)
Dr Tim Littlewood (Haematologist)
John Radcliffe Hospital
Oxford OX3 9DU

Dr James Lindsay (Gastroenterologist)
Dr John Gribben (Haemotologist)
Barts and the London NHS Trust
London E1 1BB

Dr Mark Tremmling (Gastroenterologist)
Norfork and Norwich University Hospitals
Norwich NR4 7UY

Pr Jack Satsangi (Gastroenterologist)
Dr Peter Johnson (Haematologist)
Western General Hospital
Crewe Road
Edinburgh EH4 2XU





Nottingham Digestive Diseases Centre

The University of Nottingham
E Floor, West Block, Queen's Medical Centre
Nottingham, NG7 2UH

telephone: +44 (0) 115 82 31090