Welcome to the Autologous Stem Cell Transplantation for Crohn's Disease Trial (ASTIC)
ASTIC is a multicentre, prospective, randomised phase III study conducted by the European Crohn's and Colitis Organisation (ECCO), sponsored by the Autoimmune Disease Working Party of the European Group for Blood and Marrow Transplantation (EBMT). This study is funded by a grant from the Broad Medical Research Programme.
***This trial is now closed to recruitment. Initial analysis is due March 2013 .***
Professor Chris Hawkey, Nottingham Digestive Diseases Centre; Email: firstname.lastname@example.org
Study Administration Office:
ASTIC Study Administration Office
Nottingham Digestive Diseases Centre; Email: email@example.com Tel: +44 (0) 115 8231079. Fax: +44 (0) 115 823 1409
| News |
Total number of patients transplanted is 38.
There are 4 patients left awaiting delayed transplants, the final of which is due Feb 2013
Patient recruitment is halted. Initial analysis is due in a year.
A total of 45 patients have been randomised (of these 35 have been transplanted).
A total of 39 patients have been randomised. Of these 27 patients have been transplanted.
||Nottingham consents their 13th patient |
27 patients randomised and a further 9 patients consented to the trial.
A total of 17 patients have been transplanted.
Belgium joins the ASTIC Trial.
Leuven Hospital consents 2 patients.
|20 July 2010
Edinburgh consents 4 patients in a day!
This brings the total number of patients for this site to 6.
||BARTS and the London consent their first patient. |
||All approvals completed for Switzerland; the first patient enters the trial in Zurich. |
14 patients now consented into the trial, with 7 transplants complete.
Sites with patients in trial include:
Barcelona Storms Ahead - well done to Elena Ricart and her team.
5 patients registered and a further patient for discussion.
||The first transplants take place in Nottingham and Barcelona. |
Three sites now recruiting.
Nottingham, Oxford and Barcelona have completed trial registration.
||First patient recruited in Nottingham |
Abstracts have been submitted to the following meetings:
- 6th Congress of ECCO, February 23-26, 2011, Dublin
- Digestive Diseases Week American Gastroenterology Association, Chicago, 30th May - 4th June 2009
- British Society of Gastroentereology, Glasgow, 23rd-26th March 2009
- ECCO IBD 4th Congress in Hamburg, 5-7th February 2009
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