Discovering and exploiting innate defences against infections are a focus, as are mechanisms of disease such as the recognition of chronic bacterial infections. Applied and translational aspects, such as the development of immune-competent tissue models, complement the research activities in this area.
Our researchers study interferons and STAT transcription factors to uncover mechanisms by which our immune system responds to viral and bacterial pathogens (Professor Uwe Vinkemeier, Action Medical Research Chair of Cell Biology), they research dysregulated immune function and biomarkers of disease (Professors Herb Sewell and Ian Todd, Associate Professors Paddy Tighe and Karl Wooldridge, and Assistant Professor Lucy Fairclough), and decipher novel mannose receptor pathways that recognise allergens (Associate Professor Luisa Martinez-Pomares).
Teams of our scientists are involved in multi-disciplinary research spanning life sciences, engineering and medicine that will deliver biomaterials for drug or cell delivery or therapeutic use. Professor Amir Ghaemmaghami’s bioengineering research is with the EPSRC Next Generation Biomaterials Discovery project and a number of European funded consortia (Immodgel and PANBioRA). We are also taking cross-disciplinary approaches to the study of cellular information processing and cytoskeletal dynamics (Assistant Professors Claire Friel and Alan Huett).
Our division hosts the University of Nottingham Flow Cytometry Facility, which can be accessed by internal and external users.
Antimicrobial therapy that targets specific cells in the immune system could prevent sepsis and life-threatening disease in people with pneumonia.
A protein known for its ability to guard against viral infection has been found to hinder disease therapies in animals.
Join Claire Friel and scientists from across the University and elsewhere to discuss minimally-invasive optical approaches.
Paddy Tighe, Lucy Fairclough and Ian Todd deliver new research on flu vaccine effectiveness
School of Life SciencesUniversity of NottinghamMedical School
Queen's Medical CentreNottingham NG7 2UH
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