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Clinical Stroke Trials

Clinical Trials supported by the University of Nottingham
Description Funder  Date
BASC BASC (Blood Pressure in Acute Stroke Collaboration) is an international collaborative project with the aim of producing a set of systematic reviews relating to the best management of blood pressure (including hypertension and hypotension) in patients with acute stroke. UK NHS Executive South Thames & UK NHS Executive Trent 1996 - 


A prospective, international, multicentre, randomised, parallel-group, blinded, controlled, collaborative, factorial trial to investigate the safety and efficacy of treatment with transdermal glyceryl trinitrate, a nitric oxide donor, and of stopping or continuing prior antihypertensive therapy, in patients with acute stroke (ISRCTN99414122)  Medical Research Council  2001 - 2013  
EuroHyp-1 The EuroHyp-1 trial is a pan-European, open, randomised, phase III clinical trial which will assess the benefit of therapeutic cooling in adult patients with acute ischaemic stroke. European Commission 2013 - 
PODCAST  Prevention Of Decline in Cognition After Stroke Trial (PODCAST): a factorial randomised controlled trial of blood pressure and lipid lowering

The Stroke Association & The Alzheimer's Society

2010 - 2014


Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial 2

British Heart Foundation 2015 - 
STEMS-3 Stem Cell Trial of recovery EnhanceMent after Stroke 3 (STEMS-3) Research for Patient Benefits, NIHR 2011 - 2013
TARDIS Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke British Heart Foundation 2009 - ongoing
Tranexamic acid for hyperacute primary Intracerebral Haemorrhage (TICH-2).
NIHR HTA 2013 - 2017



Stroke, Division of Clinical Neuroscience

The University of Nottingham
Clinical Sciences Building
Nottingham, NG5 1PB

telephone: +44 (0)115 823 1765