Tissue Modelling

The need to develop novel tumour models that closely mimic the in vivo tumour environment is essential for drug validation and future advances in anti-carcinoma therapy.

Current methods employed in drug testing include monolayer culture, intra-peritoneal hollow fibre and xenograft in vivo models, all of which fall short of the ideal.

Applying tissue engineering strategies to the culture of cancer cells in vitro presents a real opportunity to develop a more accurate, ethical and cost effective 3-D model for anti-carcinoma drug screening.