Ross Denton

Contact

• workRoom C 24 School of Chemistry, University Park
• work0115 951 4194
• ross.denton@nottingham.ac.uk
• http://web.me.com/rossdenton/The_Denton_Group/Home.html

Biography

Dr Denton began his research career at The University of Nottingham where he carried out his PhD studies with Professor J.C. Anderson (2001-2004). At the beginning of 2005 he moved to the Scripps Research Institute USA to carry out postdoctoral research with Professor K.C. Nicolaou. In mid 2007 he returned to the UK to take up a further postdoctoral position with Professor S.V. Ley CBE, FRS at The University of Cambridge. In September 2008 he returned to The University of Nottingham to begin his independent research career as a Lecturer in Organic Chemistry (fixed-term). In June 2009 he was appointed to a permanent lectureship.

Personal homepage: http://web.me.com/rossdenton/The_Denton_Group/Home.html

Research Summary

My research interests involve the development of new catalytic methods for the formation of carbon-heteroatom bonds and the total synthesis of natural products.

Please visit my website for more details on research projects.

Recent Publications

• DENTON, RM, AN, J, ADENIRAN, B, BLAKE, AJ, LEWIS, W and POULTON, AM, 2011. Catalytic Phosphorus(V)-Mediated Nucleophilic Substitution Reactions: Development Of A Catalytic Appel Reaction Journal Of Organic Chemistry. 76(16), 6749-6767
• DENTON, RM, SCRAGG, JT and SASKA, J, 2011. A Concise Synthesis Of 4 '-O-Methyl Honokiol Tetrahedron Letters. 52(20), 2554-2556
• LUPO, G, GESTRI, G, O'BRIEN, M, DENTON, RM, CHANDRARATNA, RAS, LEY, SV, HARRIS, WA and WILSON, SW, 2011. Retinoic Acid Receptor Signaling Regulates Choroid Fissure Closure Through Independent Mechanisms In The Ventral Optic Cup And Periocular Mesenchyme Proceedings Of The National Academy Of Sciences Of The United States Of America. 108(21), 8698-8703
• DENTON, R. M., SCRAGG, J. T., GALOFRE, A. M., GUI, X. and LEWIS, W., 2010. A concise synthesis of honokiol TETRAHEDRON. VOL 66(NUMBER 40), 8029-8035

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• LUPO, G, GESTRI, G, O'BRIEN, M, DENTON, RM, CHANDRARATNA, RAS, LEY, SV, HARRIS, WA and WILSON, SW, 2011. Retinoic Acid Receptor Signaling Regulates Choroid Fissure Closure Through Independent Mechanisms In The Ventral Optic Cup And Periocular Mesenchyme Proceedings Of The National Academy Of Sciences Of The United States Of America. 108(21), 8698-8703
• DENTON, RM, SCRAGG, JT and SASKA, J, 2011. A Concise Synthesis Of 4 '-O-Methyl Honokiol Tetrahedron Letters. 52(20), 2554-2556
• DENTON, RM, AN, J, ADENIRAN, B, BLAKE, AJ, LEWIS, W and POULTON, AM, 2011. Catalytic Phosphorus(V)-Mediated Nucleophilic Substitution Reactions: Development Of A Catalytic Appel Reaction Journal Of Organic Chemistry. 76(16), 6749-6767
• DENTON, RM and SCRAGG, JT, 2010. A Concise Synthesis Of Dunnianol Synlett. 633-635
• DENTON, RM, AN, J and ADENIRAN, B, 2010. Phosphine Oxide-Catalysed Chlorination Reactions Of Alcohols Under Appel Conditions Chemical Communications. 46(17), 3025-3027
• DENTON, RM, TANG, XP and PRZESLAK, A, 2010. Catalysis Of Phosphorus(V)-Mediated Transformations: Dichlorination Reactions Of Epoxides Under Appel Conditions Organic Letters. 12(20), 4678-4681
• DENTON, R. M., SCRAGG, J. T., GALOFRE, A. M., GUI, X. and LEWIS, W., 2010. A concise synthesis of honokiol TETRAHEDRON. VOL 66(NUMBER 40), 8029-8035
• LEY, SV, ABAD-SOMOVILLA, A, ANDERSON, JC, AYATS, C, BANTELI, R, BECKMANN, E, BOYER, A, BRASCA, MG, BRICE, A, BROUGHTON, HB, BURKE, BJ, CLEATOR, E, CRAIG, D, DENHOLM, AA, DENTON, RM, DURAND-REVILLE, T, GOBBI, LB, GOBEL, M, GRAY, BL, GROSSMANN, RB, GUTTERIDGE, CE, HAHN, N, HARDING, SL, JENNENS, DC, JENNENS, L, LOVELL, PJ, LOVELL, HJ, DE LA PUENTE, ML, KOLB, HC, KOOT, WJ, MASLEN, SL, MCCUSKER, CF, MATTES, A, PAPE, AR, PINTO, A, SANTAFIANOS, D, SCOTT, JS, SMITH, SC, SOMERS, AQ, SPILLING, CD, STELZER, F, TOOGOOD, PL, TURNER, RM, VEITCH, GE, WOOD, A and ZUMBRUNN, C, 2008. The Synthesis Of Azadirachtin: A Potent Insect Antifeedant Chemistry-A European Journal. 14(34), 10683-10704
• NICOLAOU, K. C., LISTER, T., DENTON, R. M. and GELIN, C. F., 2008. Total synthesis of artochamins F, H, I, and J through cascade reactions Tetrahedron. VOL 64(NUMBER 21), 4736-4757
• LEY, STEVEN V, ABAD-SOMOVILLA, ANTONIO, ANDERSON, JAMES C, AYATS, CARLES, BÄNTELI, ROLF, BECKMANN, EDITH, BOYER, ALISTAIR, BRASCA, MARIA G, BRICE, ABIGAIL, BROUGHTON, HOWARD B, BURKE, BRENDA J and C, 2008. The synthesis of azadirachtin: a potent insect antifeedant. Chemistry - A European Journal. 14(34), 10683-704
• MUNDAY, R.H., DENTON, R.M. and ANDERSON, J.C., 2008. Asymmetric Synthesis of 6'-Hydroxyarenarol: The Proposed Biosynthetic Precursor to Popolohuanone E J. Org. Chem.. VOL 73(NUMB 20), 8033-8038
• NICOLAOU, K.C., FREDERICK, M.O., BURTOLOSO, A.C.B., DENTON, R.M., RIVAS, F., COLE, K.P., AVERSA, R.J., GIBE, R., UMEZAWA, T. and SUZUKI, T., 2008. Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin J. Am. Chem. Soc.. VOL 130(NUMB 23), 7466-7476
• NICOLAOU, K.C., STEPAN, A.F., LISTER, T., LI, A., MONTERO, A., TRIA, G.S., TURNER, C.I., TANG, Y., WANG, J. and DENTON, R.M., 2008. Design, Synthesis, and Biological Evaluation of Platensimycin Analogues with Varying Degrees of Molecular Complexity J. Am. Chem. Soc. VOL 130(NUMB 39), 13110-13119
• NICOLAOU, KC, LISTER, T, DENTON, RM, MONTERO, A and EDMONDS, DJ, 2007. Adamantaplatensimycin: A Bioactive Analogue Of Platensimycin Angewandte Chemie-International Edition. 46(25), 4712-4714
• NICOLAOU, KC, LISTER, T, DENTON, RM and GELIN, CF, 2007. Cascade Reactions Involving Formal [2+2] Thermal Cycloadditions: Total Synthesis Of Artochamins F, H, I, And J Angewandte Chemie-International Edition. 46(39), 7501-7505
• NICOLAOU, KC, COLE, KP, FREDERICK, MO, AVERSA, RJ and DENTON, RM, 2007. Chemical Synthesis Of The Ghijk Ring System And Further Experimental Support For The Originally Assigned Structure Of Maitotoxin Angewandte Chemie-International Edition. 46(46), 8875-8879
• NICOLAOU, KC, ORTIZ, A and DENTON, RM, 2007. Metathesis Reactions In The Synthesis Of Complex Molecules Chimica Oggi-Chemistry Today. 25(5), 70-76
• NICOLAOU, K.C., ORTIZ, A. and DENTON, R.M., 2007. Metathesis reactions in the synthesis of complex molecules Chemica Oggi. VOL 25(NUMB 5), 70-77
• NICOLAOU, K. C., COLE, K. P., FREDERICK, M. O., AVERSA, R. J. and DENTON, R. M., 2007. Chemical Synthesis of the GHIJK Ring System and Further Experimental Support for the Originally Assigned Structure of Maitotoxin Angewandte Chemie International Edition. VOL 119(NUMBER 46), 9031-9035
• NICOLAOU, K. C., LISTER, T., DENTON, R. M., MONTERO, A. and EDMONDS, D. J., 2007. Adamantaplatensimycin: A Bioactive Analogue of Platensimycin Angewandte Chemie International Edition. VOL 119(NUMBER 25), 4796-4798
• NICOLAOU, K. C., LISTER, T., DENTON, R. M. and GELIN, C. F., 2007. Cascade Reactions Involving Formal [2+2] Thermal Cycloadditions: Total Synthesis of Artochamins F, H, I, and J Angewandte Chemie International Edition. VOL 119(NUMBER 39), 7645-7649
• NICOLAOU, KC, DENTON, RM, LENZEN, A, EDMONDS, DJ, LI, A, MILBURN, RR and HARRISON, ST, 2006. Stereocontrolled Synthesis Of Model Core Systems Of Lomaiviticins A And B Angewandte Chemie-International Edition. 45(13), 2076-2081
• NICOLAOU, K. C., DENTON, R. M., LENZEN, A., EDMONDS, D. J., LI, A., MILBURN, R. R. and HARRISON, S. T., 2006. Stereocontrolled Synthesis of Model Core Systems of Lomaiviticins A and B Angewandte Chemie International Edition. VOL 118(NUMBER 13), 2130-2135
• ANDERSON, JC, DENTON, RM and WILSON, C, 2005. A Biomimetic Strategy For The Synthesis Of The Tricyclic Dibenzofuran-1,4-Dione Core Of Popolohuanone E Organic Letters. 7(1), 123-125
• ANDERSON, J.C., DENTON, R.M. and WILSON, C., 2005. A biomimetic strategy for the synthesis of the tricyclic dibenzofuran-1,4-dione core of popolohuanone E Organic Letters. 7(1), 123-126
• ANDERSON, J. C., DENTON, R. M., HICKIN, H. G. and WILSON, C., 2004. Synthesis of dibenzofuran-1,4-diones using the Dotz benzannulation Tetrahedron. VOL 60(NUMBER 10), 2327-2335