School of Medicine
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PhD Projects (Self-funded vacancies)

Self-funded PhD projects are always available within our research groups. For a flavour of the type of self-funded PhD projects available, please take a look at our (non-exhaustive) list of self-funded PhD vacancies below.

Funding

Unless stated, the projects listed here do not have funding attached to them.

Funded opportunities are often available, and are advertised via the University's vacancies website, the jobs.ac.uk and FindAPhD.com websites. The University offers scholarship opportunities to international students and home/EU students. (Note: You must be in receipt of an offer to study before you can apply for a scholarship with the University of Nottingham.)

 

 

 

Search current opportunities

  • To search the table, please enter a keyword in the filter box below
  • Sort the columns by clicking on a heading
  • Once you have found a suitable project, look up your supervisor's details for more information about their research area.
Self-funded PhD projects (non-exhaustive)
DivisionSupervisorTitleKeywordsFee band*
Clinical Neuroscience Ravi P Mahajan Patient participation in preoperative assessment Anaesthesia; Patient Safety; Quality outcome; Patient satisfaction; Quality improvement; Pre-anaesthesia assessment £
Clinical Neuroscience Ravi P Mahajan Medication errors – strategies to prevent them Anaesthesia; Patient Safety; Quality outcome; Pharmacy; Medication error; Quality improvement £
Clinical Neuroscience Ravi P Mahajan Development of tools for effective handover Anaesthesia; Patient Safety; Critical Care; Quality outcome  £
Clinical Neuroscience Ravi P Mahajan Strategies to stabilize haemodynamics during anaesthesia Anaesthesia; Patient safety; Quality outcome; Quality improvement £
Clinical Neuroscience Iain Moppett Factors affecting hepatic injury following surgery in the prone position Anaesthesia; surgery; cardiovascular physiology; liver disease; clinical £££
Clinical Neuroscience Iain Moppett The anaesthetist as vector for infection Anaesthesia; surgical site infection; microbiology; hand hygiene; contamination £££
Clinical Neuroscience Iain Moppett Non-invasive prediction of fluid responsiveness in the self-ventilating awake patient Anaesthesia; critical care; surgery; cardiovascular physiology statistics; clinical; trials; monitoring £££
Clinical Neuroscience Iain Moppett Distractions and interruptions in the operating theatre Anaesthesia; surgery; patient safety; psychology; distraction; interruption £
Child Health, Obstetrics & Gynaecology Walid Maalouf The Effects of Pre-Implantation Embryo Biopsy on Further Development of the Offspring

Assisted Reproductive Treatment; ICSI; PGD; Embryo Biopsy; Molecular Biology

££
Child Health, Obstetrics & Gynaecology Walid Maalouf, Louise Mullany The Influence of Linguistic Strategies on the Patients’ Experience of Assisted Reproductive Treatment Assisted Reproductive Treatment; Linguistics; Language; Fertility; IVF; Reproductive Sciences £
Respiratory Medicine Ian Sayers

Genetic and epigenetic regulation of airway epithelial cell function in asthma

asthma, genetic susceptibility, epigenetics, functional analyses, primary airway cell models

£££
Respiratory Medicine Ian Sayers

Translating recently identified asthma susceptibility genes to new insights for disease mechanisms

asthma, genetic suscepitibility, functional analyses, primary airway cell models £££
Respiratory Medicine Ian Sayers

Structure-function studies on protein coding region variants associated with asthma susceptibility

asthma, genetic susceptibility, functional analyses, structure determination, primary airway cell models £££
Respiratory Medicine Ian Sayers

Identification of altered mechanisms in the bronchial epithelium in asthma using transcriptomics and functional assays

asthma, genetic susceptibility, functional analyses, structure determination, primary airway cell models £££
Respiratory Medicine Ian Sayers

Defining the contribution of SNPs identified in GWAS to clinical variables defining asthma

asthma, genetic susceptibility, clinical and immunological analyses, cohort studies  £££
Respiratory Medicine Ian Sayers

Translating recently identified lung function genes to new insights for lung biology

lung function, COPD, genetic susceptibility, functional analyses, primary airway cell models £££
Respiratory Medicine Galina Pavlovskaya

Hyperpolarized 83Kr as a novel contr ast agent for magnetic resonance imaging (MRI) of lungs

Asthma; Lung imaging MRI; hyperpolarized 83Kr; 129Xe; 3He; IPF; ALI ££
Medical Sciences and Graduate Entry Medicine KL Cheung / Andrew Green

Biological assessment – part of a novel tool to optimise treatment of primary breast cancer in older women

breast cancer; Elderly £££
Medical Sciences and Graduate Entry Medicine KL Cheung Developing a geriatric assessment tool for older women with early primary breast cancer Breast cancer; Elderly  £
Cancer and Stem Cells David Bates Tumour angiogenesis and the control of splicing PDF format Cancer; angiogenesis, VEGF, RNA, splicing £££
Cancer and Stem Cells David Bates RNA binding proteins that control tumour growth by regulating blood vessel growth PDF format Cancer; angiogenesis, VEGF, RNA, splicing £££
Cancer and Stem Cells David Bates The structure of the human glomerulus PDF format Fluid dynamics, mathematical modelling, electron microscopy £
Cancer and Stem Cells David Bates New treatments for age related macular degeneration PDF format Ophthalmology; angiogenesis, VEGF, RNA, splicing £££
Cancer and Stem Cells David Bates Diabetic microvascular complications – the role of the permeability layer PDF format Ophthalmology; neurodegeneration, VEGF, mitochondria £££
Cancer and Stem Cells David Bates Restoring blood flow in cardiovascular disease - collaterals as keys to therapy PDF format VEGF, angiogenesis, ischemia, cardiovascular disease £££
Cancer and Stem Cells David Bates Control of breeding season by microvascular remodelling in the sheep PDF format Pituitary, vascular remodelling, reproduction, sheep, endocrinology £
Cancer and Stem Cells Sarah Storr New therapeutic targets in breast cancer breast cancer, metastasis, prognosis £££
Cancer and Stem Cells Andrew Jackson Immune regulation by DNA damage-response Pathways in Dendritic CellsPDF format Dendritic cell, immunity, DNA-repair, ATM, IL-23, Th17, regulatory T-cell, transcription factor ££££
Cancer and Stem Cells Andrew Jackson The impact of tumour microenvironment on cross talk between Antigen Presenting Cells and Stromal FibroblastsPDF format Dendritic cell, macrophage, immunity, T-cell, fibroblast, stroma, cancer ££££
Cancer and Stem Cells Andrew Jackson Targeting the p38 MAPK signalling pathways in GlioblastomaPDF format T-cell, dendritic cell, macrophage, immunity, cancer, signalling pathway, MAPK ££££
Cancer and Stem Cells Anna
Grabowska
Epigenetic regulation of EMT in 3D patient-relevant lung cancer models Epigenetics; Pre-clinical modelling; tumour microenvironment; invasion.metastasis;
paracrine signalling
££££
Cancer and Stem Cells Anna
Grabowska
Maintenance of a mesenchymal stem cell niche in pancreatic cancer (PCa) models Pre-clinical modelling; tumour microenvironment; stem cells; paracrine signalling ££££ 
Cancer and Stem Cells Anna
Grabowska
Paracrine signalling in breast cancer  - role of kinases in growth promotion Paracrine signalling; tumour microenvironment; drug sensitivity; Pre-clinical modelling  ££££
Cancer and Stem Cells Anna
Grabowska
Functional analysis of prostate cancer-associated
miRNAs using patient-derived xenografts
miRNAs; tumour microenvironment; exosomes; paracrine signalling  ££££
Child Health, Obstetrics & Gynaecology Beth Coyle Modelling evolution of metastasis in paediatric medulloblastoma using 3D models PDF format Metastasis, cancer stem cells, multidrug resistance £££
Child Health, Obstetrics & Gynaecology Beth Coyle Modelling evolution of metastasis in paediatric medulloblastoma using tailored 3D biomatrices PDF format

Metastasis, cancer stem cells, multidrug resistanc

£££
Child Health, Obstetrics & Gynaecology Ruman Rahman / Stuart Smith Targeting residual brain cancer cells from the lethal invasive margin of Glioblastoma Brain cancer, Glioblastoma, Intra-tumour heterogeneity, precision medicine, invasive margin £££
Child Health, Obstetrics & Gynaecology Ruman Rahman Integrated genome-wide analyses of glioblastoma intra-tumour
heterogeneity: a framework for personalised medicine
Brain cancer, tumour heterogeneity, next-generation sequencing, patient-tailored pharmacology £££
Cancer and Stem Cells Abdolrahman Shams Nateri Understanding cancer stem cells in colorectal cancer using 3D organoid and CRISPR/Cas9 methodologies

Colorectal cancer stem cells, Tissue organoids, Proteomics Mass spectrometry, Cancer Bioinformatics, Cancer biomarkers, 3D cell cultures

££££
Cancer and Stem Cells Abdolrahman Shams Nateri In vitro and in vivo approaches to investigate the regulation of the intestinal stem cell niche in the gastrointestinal tract development and cancer Cancer; Intestinal stem cells; stem cells; Loss & gain of gene function; Signalling & Transcription £££
Psychiatry and Applied Psychology Roshan dasNair and Cris Constantinescu Smoking cessation and multiple sclerosis smoking cessation, service developments, complex interventions, multiple sclerosis £
Psychiatry and Applied Psychology Roshan dasNair and Kate Radford Return to work after a diagnosis of multiple sclerosis return to work, employment, service developments, complex interventions, multiple
sclerosis
£
Psychiatry and Applied Psychology Roshan dasNair Emotional support around the time of multiple sclerosis diagnosis, relapse, or transition
to secondary progressive stage
psychological support, psychological interventions, service developments, complex interventions,
multiple sclerosis
£
Psychiatry and Applied Psychology / Rehabilitation and Ageing Fiona Marshall and John Gladman Localities of Community Dementia Care Frailty, respite, well-being, sense of belonging within communities. Models of community care in localities; design and delivery of services. Rural, remote, suburban, urban, inner city  
Psychiatry and Applied Psychology / Rehabilitation and Ageing Fiona Marshall and John Gladman Care Farms as a model of community care and supporting older people The impact of care farms in rural & urban community care. What works well and
why?
 
Pychiatry and Applied Psychology / Rehabilitation and Ageing Ana Basiri and Fiona Marshall Rural Health Geographies and living well in older age Uses of human geography to examine the realities of growing old in rural and remote areas. Liminalities, where is home?  
Psychiatry and Applied Psychology Amanda Griffiths and Fiona Marshall

Rural health service provider workforce

Workforce issues related to managing care service design and delivery in rural areas  
Psychiatry and Applied Psychology / Epidemiology and Public Health Sarah Lewis and Fiona Marshall Rural living in older age; epidemiology factors of living in a rural location Epidemiology, environmental factors, lifestyle factors among established and newly arrived older people in the UK.  
Psychiatry and Applied Psychology/ Veterinary Medicine and Science John Harris, Kate White and Fiona Marshall What’s in it for the animals? Animal welfare in relation to care farms and similar
settings.
Animals living on care farms: benefits, needs, considerations? Towards the development of recommendations for animal welfare on care farms and similar therapeutic
settings
 
Rehabilitation and Ageing John Gladman, Adam Gordon, Paul Greenhaff

Sarcopenia in response to acute stress

frailty  
Rehabilitation and Ageing Kate Radford Supporting job retention in people with cancer PDF format Cancer, work, randomised controlled trials, vocational rehabilitation £
Rehabilitation and Ageing John Gladman / Simon Conroy / Adam Gordon / Tahir (Tash) Masud Comprehensive geriatric assessment in emergency and acute care Comprehensive geriatric assessment, acute care £
Rehabilitation and Ageing John Gladman Exercise interventions in older people with frailty older people, exercise, frailty £
Rehabilitation and Ageing John Gladman / Professor Rowan Harwood End of life care in older people with frailty older people, frailty £
Rehabilitation and Ageing Pip Logan Falls in care homes Dementia, falls, injuries, care homes, randomised controlled trials, implementation £
Rehabilitation and Ageing John Gladman / Rowan Harwood / Tom Dening / Adam Gordon / Sarah Goldberg Delirium prevention in care homes (or other settings) Delirium, care homes £
Rehabilitation and Ageing Rowan Harwood / Tahir (Tash) Masud / Pip Logan / John Gladman Falls prevention in people with dementia Dementia, falls £
Rehabilitation and Ageing Kate Radford Cognitive screening for 'fitness to drive' in dementia; understanding implementation barriers PDF format Dementia, cognitive assessment, driving, implementation £
Child Health, Obstetrics & Gynaecology Michael SymondsHelen Budge Environmental regulation of brown adipose tissue function health and well being, imaging obesity, adipose tissue, development, growth ££
Child Health, Obstetrics & Gynaecology Michael Symonds, Helen Budge Early life nutrition, metabolic development and health Nutrition; reproduction; obesity; child health; endocrinology; development ££
Nottingham Digestive Diseases Centre Karen Robinson Regulatory T-cell responses to Helicobacter pylori in health and disease Immunity to gastro-intestinal infection Helicobacter pylori; regulatory T-cells; immunosuppressive function; protection from disease £££
Nottingham Digestive Diseases Centre Y R Mahida Investigation of interactions between host cells and C. difficile toxins Infection, Immunity and Inflammation; colitis; apoptosis; receptors; cell signalling; cytokines ££
Rehabilitation and Ageing Heather Buchanan

Exploring parent-child communication about kidney disease and developing support resources

Communication tools, child, adolescents, prognosis £
Rehabilitation and Ageing Heather Buchanan Psychological interventions to improve oral health in low socioeconomic groups Behaviour change, interventions, tooth-brushing, diet £
Nottingham Digestive Diseases Centre Dileep N Lobo, John Hammond, Salvatore Papa Understanding how the liver heals: the pathophysiology of sepsis induced liver failure PDF format Liver surgery and regeneration; JNK signalling; sepsis ££
Clinical Neuroscience Henryk Faas Molecular magnetic resonance imaging of neuroinflammation in the brain PDF format MRI; neuroinflammation £££
Child Health, Obstetrics & Gynaecology Don Sharkey Computational modelling of stress associated newborn brain injury PDF format premature; newborn; brain injury; modelling ££
Child Health, Obstetrics & Gynaecology Don Sharkey Development of a neonatal nutrition tool to improve long-term outcomes PDF format premature; newborn; nutrition; outcome £
Rehabilitation and Ageing  Tahir Masud (Nottingham University Hospitals), Pip Logan, John Gladman Chair based exercise in hospital settings Older people, exercise £
Cancer and Stem Cells Stewart Martin Breast cancer lymphovascular invasion (LVI) and metastasis Lymphatic biology; Metastasis; Inflammation; Macrophage; Cytokines; Inflammatory breast cancer ££
Cancer and Stem Cells Stewart Martin Targeting redox homeostasis in cancer Thioredoxin; Glutathione; Breast cancer; Pancreatic cancer; Cancer biology; Biomarkers ££
Cancer and Stem Cells Stewart Martin The role of calpain and calpastatin in cancer biology and cellular ageing Breast cancer; Ovarian cancer; cell Biology; Signalling; Cancer therapy; Invasion and migration ££
Cancer and Stem Cells Stewart Martin Improving radiotherapy via novel drug-radiation interactions Radiation biology; Combined therapies; Biomarkers; Drug interactions; Radiotherapy; Breast cancer; Pancreatic cancer ££
Cancer and Stem Cells Alan McIntyre Epigenetic regulation of gene expression in tumour hypoxia Cancer, epigenetics, hypoxia, acetylation, tumour microenvironment, functional analyses, 3D culture £££
Cancer and Stem Cells Alan McIntyre Understanding the importance of stress responses in cancer adaptation

Cancer, hypoxia, acidosis, tumour microenvironment, functional analyses, 3D culture

£££
Cancer and Stem Cells Abdolrahman Shams Nateri Differentiation of human pluripotent stem cells into intestinal tissue in vitro Stem cells, iPS, Wnt/ -catenin signalling

££££

Cancer and Stem Cells Abdolrahman Shams Nateri Identification of small molecule drugs that selectively target cancer stem cells for differentiation (Differentiation Therapy) Cancer, stem cells, differentiation, pluripotent ££££
Respiratory Medicine Simon JohnsonDebbie Clements Modelling Lymphangioleiomyomatosis with in vitro co-culture systems PDF format Respiratory Cell Biology; Cell culture; modelling; translational research £££
Respiratory Medicine Simon JohnsonDebbie Clements Expression and Activity of Matrix Metalloproteinases in lung remodelling PDF format Respiratory Cell Biology; Cell culture; modelling; translational research  
Respiratory Medicine Linhua Pang Role of bacteria and host interactions in lung inflammation in cystic fibrosis Respiratory Cell Biology; Bacterial infection; lung inflammation; chemokines; cystic fibrosis; airway structural cells; myofibroblast differentiation; epigenetics; gene expression; pulmonary fibrosis ££££
Respiratory Medicine Linhua Pang Molecular mechanisms of myofibroblast differentiation in pulmonary fibrosis Respiratory Cell Biology; Bacterial infection; lung inflammation; chemokines; cystic fibrosis; airway structural cells; myofibroblast differentiation; epigenetics; gene expression; pulmonary fibrosis ££££
Cancer and Stem Cells Judith Ramage Antibodies to novel costimulatory molecules on T cells  antibodies, T cells ££££
Cancer and Stem Cells Judith Ramage Increasing T cell migration to tumours T cells, tumour ££££
Cancer and Stem Cells Virginie Sottile Regulation of adult stem cell differentiation towards therapeutic cell lineages stem cell biology, developmental biology, tissue engineering, regenerative medicine £££
Cancer and Stem Cells Chris Denning Developing new treatments for cardiovascular disease and sudden cardiac death by coupling stem cells with Cas9/CRISPR gene editing Human induced pluripotent stem cells; Cas9/CRISPR gene editing; disease modelling; cardiomyocytes; engineered heart tissues; robotics and automation; pharmacology £££
Cancer and Stem Cells Alexey Ruzov Biological roles of 5-hydroxymethylcytosine oxidation during neural and glial differentiation Stem cells, epigenetics, DNA methylation, developmental biology, regenerative medicine, 5-hydroxymethylcytosine £££
Cancer and Stem Cells Alexey Ruzov and Matthew Loose (School of Biology) The dynamics of modified forms of 5-methylcytosine during spermatogenesis (The project would include bioinformatics-based analysis of deep sequencing data, candidates with bioinformatics background to be considered) Stem cells, bioinformatics, epigenetics, DNA methylation, developmental biology, 5-hydroxymethylcytosine £££
Clinical Neuroscience Nikola Sprigg and Philip Bath Tranexamic acid for hyperacute spontaneous IntraCerebral Haemorrhage  Stroke, Haemorrhage, Outcome, Randomised controlled trials £
Clinical Neuroscience Philip Bath Secondary prevention of post stroke cognitive impairment stroke, dementia, cognitive impairment, nitric oxide, nitrate £
Clinical Neuroscience Philip Bath Treatment of post stroke dysphagia Stroke, Dysphagia, Swallowing impairment, Electrical stimulation £
Clinical Neuroscience Philip Bath Glyceryl trinitrate for ST elevation myocardial infarction STEMI, Myocardial infarction, Nitric oxide, Nitrate £
Clinical Neuroscience Ulvi Bayraktutan and Rebecca Trueman (School of Life Sciences) Can outgrowth endothelial cells restore neurovascular integrity and function after ischaemic stroke?  Ischaemic injury, blood-brain barrier, brain oedema, endothelial progenitor cells £££
Primary Care Tim Coleman Feasibility RCT of nicotine preloading for stopping smoking in pregnancy: a new approach to cessation smoking, smoking in pregnancy £
Rheumatology, Orthopaedics and Dermatology Gwen Fernandes, Mark Batt, Weiya Zhang and Michael Doherty Foot and Ankle Osteoarthritis in ex-professional footballers compared to the general
population

Foot and ankle osteoarthritis, professional football, lower limb, pain  

£
Rheumatology, Orthopaedics and Dermatology Weiya Zhang, Gwen Fernandes and Michael Doherty

Examining the therapeutic effects of patient-physician interaction

Patient-physician interaction, contextual elements, contextual effects, osteoarthritis

£

  

* Fee band key (international students only)

  • £= Low cost research
  • ££ = Laboratory-based research
  • £££ = High cost lab-based research
  • ££££ = Technically-intensive/specialised research projects with high consumable costs
  • £££££ = Exceptionally technically-intensive/specialised research projects with high consumable costs

More information on postgraduate research course fees

 

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